Targeting altered calcium homeostasis and uncoupling protein‐2 promotes sensitivity in drug‐resistant breast cancer cells

Calcium homeostasis and cancer: insights from endoplasmic reticulum-centered organelle communications

(2022) Shanliang Zheng et al.   TRENDS IN CELL BIOLOGY

Morphological evaluation of MDA-MB-231 human breast cancer cells treated with DMEM extract of Turkish propolis

(2021) Meltem Uçar et al.   TROPICAL JOURNAL OF PHARMACEUTICAL RESEARCH

Apoptosis Deregulation and the Development of Cancer Multi-Drug Resistance

(2021) Christiana M. Neophytou et al.   Cancers

Sarco/Endoplasmic Reticulum Calcium ATPase Inhibitors: Beyond Anticancer Perspective

(2020) Lucie Peterková et al.   JOURNAL OF MEDICINAL CHEMISTRY

Anti-Cancer Agents in Proliferation and Cell Death: The Calcium Connection

(2019) Elizabeth Varghese et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New Insights into Mechanisms of Cisplatin Resistance: From Tumor Cell to Microenvironment

(2019) Shang-Hung Chen et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cisplatin-resistant triple-negative breast cancer subtypes: multiple mechanisms of resistance

(2019) David P. Hill et al.   BMC CANCER

Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses

(2019) Xuewei Liu et al.   VETERINARY MICROBIOLOGY

UCP2 promotes proliferation and chemoresistance through regulating the NF-κB/β-catenin axis and mitochondrial ROS in gallbladder cancer

(2019) Jianhua Yu et al.   BIOCHEMICAL PHARMACOLOGY

A temporal examination of calcium signaling in cancer- from tumorigenesis, to immune evasion, and metastasis

(2018) MengMeng Xu et al.   Cell and Bioscience

CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes

(2017) Maik Dahlhoff et al.   FEBS Journal

Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response

(2017) Pankaj Sehgal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Opposite response to hypoxia by breast cancer cells between cell proliferation and cell migration: A clue from microRNA expression profile

(2017) Ming Zhang et al.   Oncology Letters

UCP2 expression may represent a predictive marker of neoadjuvant chemotherapy effectiveness for locally advanced uterine cervical cancer

(2017) Kenji Imai et al.   Oncology Letters

MICU1 drives glycolysis and chemoresistance in ovarian cancer

(2017) Prabir K. Chakraborty et al.   Nature Communications

Thermogenic protein UCP1 and UCP3 expression in non-small cell lung cancer: relation with glycolysis and anaerobic metabolism

(2017) Giatromanolaki Alexandra et al.   Cancer Biology & Medicine

Altered calcium signaling in cancer cells

(2015) Teneale A. Stewart et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

UCP2 inhibition sensitizes breast cancer cells to therapeutic agents by increasing oxidative stress

(2015) Daniel Gabriel Pons et al.   FREE RADICAL BIOLOGY AND MEDICINE

Thapsigargin—From Thapsia L. to Mipsagargin

(2015) Trine Andersen et al.   MOLECULES

Tolerance to endoplasmic reticulum stress mediates cisplatin resistance in human ovarian cancer cells by maintaining endoplasmic reticulum and mitochondrial homeostasis

(2015) YE XU et al.   ONCOLOGY REPORTS

Multidrug Resistance Protein 1 (MRP1, ABCC1), a “Multitasking” ATP-binding Cassette (ABC) Transporter

(2014) Susan P. C. Cole   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion channels and transporters in the development of drug resistance in cancer cells

(2014) E. K. Hoffmann et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Mitochondrial recoupling: a novel therapeutic strategy for cancer?

(2011) G Baffy et al.   BRITISH JOURNAL OF CANCER

Enhancing Effect of Hydroxypropyl-β-cyclodextrin on the Intestinal Absorption Process of Genipin

(2011) Ye Zhang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular Stratification of Triple-Negative Breast Cancers

(2011) C. M. Perou   ONCOLOGIST

Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

(2011) Vanniarajan Ayyasamy et al.   PLoS One

What made sesquiterpene lactones reach cancer clinical trials?

(2010) Akram Ghantous et al.   DRUG DISCOVERY TODAY

Genipin-Induced Inhibition of Uncoupling Protein-2 Sensitizes Drug-Resistant Cancer Cells to Cytotoxic Agents

(2010) Ryan J. Mailloux et al.   PLoS One

Hormone Action in the Mammary Gland

(2010) C. Brisken et al.   Cold Spring Harbor Perspectives in Biology

The Mitochondrial Uncoupling Protein-2 Promotes Chemoresistance in Cancer Cells

(2008) Z. Derdak et al.   CANCER RESEARCH

Hereditary breast cancer: new genetic developments, new therapeutic avenues

(2008) Philippe M. Campeau et al.   HUMAN GENETICS

Co-application of arsenic trioxide (As2O3) and cisplatin (CDDP) on human SY-5Y neuroblastoma cells has differential effects on the intracellular calcium concentration ([Ca2+]i) and cytotoxicity

(2008) Dennis Alexander Günes et al.   NEUROTOXICOLOGY

A modified methylene blue assay for accurate cell counting

(2008) Dana L. Felice et al.   Journal of Functional Foods

IP3 receptor antagonist, 2-APB, attenuates cisplatin induced Ca2+-influx in HeLa-S3 cells and prevents activation of calpain and induction of apoptosis

(2007) F Splettstoesser et al.   BRITISH JOURNAL OF PHARMACOLOGY