Ion channels and transporters in the development of drug resistance in cancer cells

TMEM16F is a component of a Ca2+-activated Cl− channel but not a volume-sensitive outwardly rectifying Cl− channel

(2013) Takahiro Shimizu et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Targeting apoptosis by the remodelling of calcium-transporting proteins in cancerogenesis

(2013) Charlotte Dubois et al.   FEBS Journal

TMEM16F (Anoctamin 6), an anion channel of delayed Ca2+activation

(2013) Søren Grubb et al.   JOURNAL OF GENERAL PHYSIOLOGY

KCNN4 Channels participate in the EMT induced by PRL-3 in colorectal cancer

(2013) Wei Lai et al.   MEDICAL ONCOLOGY

New Insight into P-Glycoprotein as a Drug Target

(2012) Albert Breier et al.   Anti-Cancer Agents in Medicinal Chemistry

Inhibition of Ca2+-activated Cl− channel ANO1/TMEM16A expression suppresses tumor growth and invasiveness in human prostate carcinoma

(2012) Wen Liu et al.   CANCER LETTERS

TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression

(2012) U. Duvvuri et al.   CANCER RESEARCH

Disruption of the interaction between PMCA2 and calcineurin triggers apoptosis and enhances paclitaxel-induced cytotoxicity in breast cancer cells

(2012) R. R. Baggott et al.   CARCINOGENESIS

Inhibition of Na+-K+-2Cl–Cotransporter isoform 1 Accelerates Temozolomidemediated Apoptosis in Glioblastoma Cancer Cells

(2012) Jehad Algharabil et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug Resistance

(2012) K. G. Chen et al.   CLINICAL CANCER RESEARCH

Osmotic Stress Resistance Imparts Acquired Anti-apoptotic Mechanisms in Lymphocytes

(2012) Carl D. Bortner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ion channnels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis

(2011) V'yacheslav Lehen'kyi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Ano1 as a regulator of proliferation

(2011) Jennifer E. Stanich et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.

(2011) Oleg Y. Dmitriev   Biochemistry and Cell Biology

Reversal of Imatinib resistance in BCR-ABL-positive leukemia after inhibition of the Na+/H+ exchanger

(2011) Weina Jin et al.   CANCER LETTERS

Pinpointing Differences in Cisplatin-induced Apoptosis in Adherent and Non-adherent Cancer Cells

(2011) Hanne S. Tastesen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Dysfunction of volume-sensitive chloride channels contributes to cisplatin resistance in human lung adenocarcinoma cells

(2011) Xian-jun Min et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis

(2010) Mihalis I. Panayiotidis et al.   APOPTOSIS

NBCn1 and NHE1 expression and activity in ΔNErbB2 receptor-expressing MCF-7 breast cancer cells: Contributions to pHi regulation and chemotherapy resistance

(2010) G. Lauritzen et al.   EXPERIMENTAL CELL RESEARCH

Down-regulation of Orai3 arrests cell-cycle progression and induces apoptosis in breast cancer cells but not in normal breast epithelial cells

(2010) Malika Faouzi et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Calcium-dependent phospholipid scrambling by TMEM16F

(2010) Jun Suzuki et al.   NATURE

Membrane transporters in drug development

(2010)   NATURE REVIEWS DRUG DISCOVERY

The zinc-finger protein KCMF1 is overexpressed during pancreatic cancer development and downregulation of KCMF1 inhibits pancreatic cancer development in mice

(2010) S Beilke et al.   ONCOGENE

PMCA2 regulates apoptosis during mammary gland involution and predicts outcome in breast cancer

(2010) J. VanHouten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ion channels and the hallmarks of cancer

(2010) Natalia Prevarskaya et al.   TRENDS IN MOLECULAR MEDICINE

Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells

(2010) M Flourakis et al.   Cell Death & Disease

Deregulation of apoptotic volume decrease and ionic movements in multidrug-resistant tumor cells: role of chloride channels

(2009) K. A. Poulsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Involvement of tyrosine phosphatase CD45 in apoptosis

(2009) Geneviève Dupéré-Minier et al.   APOPTOSIS

Functional TauT Protects Against Acute Kidney Injury

(2009) X. Han et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

UA62784, a novel inhibitor of centromere protein E kinesin-like protein

(2009) M. C. Henderson et al.   MOLECULAR CANCER THERAPEUTICS

Physiology of Cell Volume Regulation in Vertebrates

(2009) Else K. Hoffmann et al.   PHYSIOLOGICAL REVIEWS

Effects of osmotic stress on the activity of MAPKs and PDGFR-β-mediated signal transduction in NIH-3T3 fibroblasts

(2008) M.-B. Nielsen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Hypertonicity-induced cation channels rescue cells from staurosporine-elicited apoptosis

(2008) Tomohiro Numata et al.   APOPTOSIS

Altered localisation of the copper efflux transporters ATP7A and ATP7B associated with cisplatin resistance in human ovarian carcinoma cells

(2008) Ganna V Kalayda et al.   BMC CANCER

Markers involved in resistance to cytotoxics and targeted therapeutics in pancreatic cancer

(2008) Ghassan El Maalouf et al.   CANCER TREATMENT REVIEWS

Targeting Ion Channels in Cancer: A Novel Frontier in Antineoplastic Therapy

(2008) A. Arcangeli et al.   CURRENT MEDICINAL CHEMISTRY

The two-pore domain potassium channel TASK3 functionally impacts glioma cell death

(2008) Sven G. Meuth et al.   JOURNAL OF NEURO-ONCOLOGY