Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response
Published 2017 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Inhibition of the sarco/endoplasmic reticulum (ER) Ca2+-ATPase by thapsigargin analogs induces cell death via ER Ca2+depletion and the unfolded protein response
Authors
Keywords
-
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 292, Issue 48, Pages 19656-19673
Publisher
American Society for Biochemistry & Molecular Biology (ASBMB)
Online
2017-10-03
DOI
10.1074/jbc.m117.796920
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A prodrug-doped cellular Trojan Horse for the potential treatment of prostate cancer
- (2016) Oren Levy et al. BIOMATERIALS
- Mipsagargin, a novel thapsigargin-based PSMA-activated prodrug: results of a first-in-man phase I clinical trial in patients with refractory, advanced or metastatic solid tumours
- (2016) D Mahalingam et al. BRITISH JOURNAL OF CANCER
- Autophagy: a druggable process that is deregulated in aging and human disease
- (2015) Guido Kroemer JOURNAL OF CLINICAL INVESTIGATION
- Opposing unfolded-protein-response signals converge on death receptor 5 to control apoptosis
- (2014) M. Lu et al. SCIENCE
- Modulation of intracellular calcium homeostasis blocks autophagosome formation
- (2013) Nikolai Engedal et al. Autophagy
- Differential effects of thapsigargin analogues on apoptosis of prostate cancer cells
- (2013) Charlotte Dubois et al. FEBS Journal
- Unfolded Protein Response Signaling and Metabolic Diseases
- (2013) Jaemin Lee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tracing Cytoplasmic Ca2+ Ion and Water Access Points in the Ca2+-ATPase
- (2012) Maria Musgaard et al. BIOPHYSICAL JOURNAL
- Engineering a Prostate-Specific Membrane Antigen-Activated Tumor Endothelial Cell Prodrug for Cancer Therapy
- (2012) S. R. Denmeade et al. Science Translational Medicine
- Critical Roles of Hydrophobicity and Orientation of Side Chains for Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase with Thapsigargin and Thapsigargin Analogs
- (2010) Anne-Marie L. Winther et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The sarcoplasmic Ca2+-ATPase: design of a perfect chemi-osmotic pump
- (2010) Jesper V. Møller et al. QUARTERLY REVIEWS OF BIOPHYSICS
- Orai1 contributes to the establishment of an apoptosis-resistant phenotype in prostate cancer cells
- (2010) M Flourakis et al. Cell Death & Disease
- STIM and Orai: Dynamic Intermembrane Coupling to Control Cellular Calcium Signals
- (2009) Xiaoxiang Deng et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Amino acid containing thapsigargin analogues deplete androgen receptor protein via synthesis inhibition and induce the death of prostate cancer cells
- (2009) D. J. Vander Griend et al. MOLECULAR CANCER THERAPEUTICS
- Intracellular death platform steps-in: Targeting prostate tumors via endoplasmic reticulum (ER) apoptosis
- (2008) Steven R. Schwarze et al. PROSTATE
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now