Pericyte-Mediated Molecular Mechanisms Underlying Tissue Repair and Functional Recovery after Ischemic Stroke

Pericyte-to-endothelial cell signaling via vitronectin-integrin regulates blood-CNS barrier

(2022) Swathi Ayloo et al.   NEURON

Phagocytic microglia and macrophages in brain injury and repair

(2022) Fang Yu et al.   CNS Neuroscience & Therapeutics

Low-dose sodium-glucose cotransporter 2 inhibitor ameliorates ischemic brain injury in mice through pericyte protection without glucose-lowering effects

(2022) Masamitsu Takashima et al.   Communications Biology

Unraveling the potential of endothelial progenitor cells as a treatment following ischemic stroke

(2022) Antía Custodia et al.   Frontiers in Neurology

PDGFRβ-positive cell-mediated post-stroke remodeling of fibronectin and laminin α2 for tissue repair and functional recovery

(2022) Tomoya Shibahara et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Recombinant Human Perlecan DV and Its LG3 Subdomain Are Neuroprotective and Acutely Functionally Restorative in Severe Experimental Ischemic Stroke

(2022) Ifechukwude Joachim Biose et al.   Translational Stroke Research

Relationship Between Acute Neurological Function and Long-Term Prognosis in Patients with Large Arterial Occlusions

(2021) Kotaro Tatebayashi et al.   Journal of Stroke & Cerebrovascular Diseases

β-Cell Function and Clinical Outcome in Nondiabetic Patients With Acute Ischemic Stroke

(2021) Takuya Kiyohara et al.   STROKE

Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions

(2021) David O. Dias et al.   Nature Communications

AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke

(2021) Natsumi Maehara et al.   Cell Reports

Protein Nanoparticles Modified with PDGF-B as a Novel Therapy After Acute Cerebral Infarction

(2021) Soh Takagishi et al.   eNeuro

Insulin Signaling Via Retinal Pericytes, New Insights and Potential Implications in Diabetic Retinopathy

(2021) Ali M Aldibbiat   ENDOCRINOLOGY

Smoking Status and Functional Outcomes After Acute Ischemic Stroke

(2020) Ryu Matsuo et al.   STROKE

Brain Cleanup as a Potential Target for Poststroke Recovery

(2020) Shun-Ming Ting et al.   STROKE

Reciprocal Interaction Between Pericytes and Macrophage in Poststroke Tissue Repair and Functional Recovery

(2020) Tomoya Shibahara et al.   STROKE

Mural cell-derived laminin-α5 plays a detrimental role in ischemic stroke

(2019) Abhijit Nirwane et al.   Acta Neuropathologica Communications

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood–brain barrier

(2019) Kuniyuki Nakamura et al.   JOURNAL OF CELL BIOLOGY

Macrophages reprogram after ischemic stroke and promote efferocytosis and inflammation resolution in the mouse brain

(2019) Wenting Zhang et al.   CNS Neuroscience & Therapeutics

Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

(2018) Axel Montagne et al.   NATURE MEDICINE

Insulin resistance and clinical outcomes after acute ischemic stroke

(2018) Tetsuro Ago et al.   NEUROLOGY

A-Kinase Anchor Protein 12 Is Required for Oligodendrocyte Differentiation in Adult White Matter

(2018) Takakuni Maki et al.   STEM CELLS

Basement membrane and stroke

(2018) Yao Yao   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain regulatory T cells suppress astrogliosis and potentiate neurological recovery

(2018) Minako Ito et al.   NATURE

Basement membrane and blood–brain barrier

(2018) Lingling Xu et al.   JOURNAL OF INVESTIGATIVE MEDICINE

Sodium glucose cotransporter 2 in mesangial cells and retinal pericytes and its implications for diabetic nephropathy and retinopathy

(2017) Masarori Wakisaka et al.   GLYCOBIOLOGY

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

(2017) Takashi Shichita et al.   NATURE MEDICINE

Interaction of reactive astrocytes with type I collagen induces astrocytic scar formation through the integrin–N-cadherin pathway after spinal cord injury

(2017) Masamitsu Hara et al.   NATURE MEDICINE

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

(2017) Kassandra Kisler et al.   NATURE NEUROSCIENCE

Early Reperfusion After Brain Ischemia Has Beneficial Effects Beyond Rescuing Neurons

(2017) Masaki Tachibana et al.   STROKE

Tissue Myeloid Progenitors Differentiate into Pericytes through TGF-β Signaling in Developing Skin Vasculature

(2017) Tomoko Yamazaki et al.   Cell Reports

A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS

(2017) Seiji Yamamoto et al.   Scientific Reports

Possible involvement of basic FGF in the upregulation of PDGFRβ in pericytes after ischemic stroke

(2016) Kuniyuki Nakamura et al.   BRAIN RESEARCH

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Adult Neural Stem Cells from the Subventricular Zone Give Rise to Reactive Astrocytes in the Cortex after Stroke

(2015) Maryam Faiz et al.   Cell Stem Cell

Involvement of platelet-derived growth factor receptor β in fibrosis through extracellular matrix protein production after ischemic stroke

(2015) Noriko Makihara et al.   EXPERIMENTAL NEUROLOGY

Demyelination as a rational therapeutic target for ischemic or traumatic brain injury

(2015) Hong Shi et al.   EXPERIMENTAL NEUROLOGY

Endothelial progenitor cells in ischemic stroke: an exploration from hypothesis to therapy

(2015) Ya-Feng Li et al.   Journal of Hematology & Oncology

Regional Blood Flow in the Normal and Ischemic Brain Is Controlled by Arteriolar Smooth Muscle Cell Contractility and Not by Capillary Pericytes

(2015) Robert A. Hill et al.   NEURON

Potential interactions between pericytes and oligodendrocyte precursor cells in perivascular regions of cerebral white matter

(2015) Takakuni Maki et al.   NEUROSCIENCE LETTERS

Brain Vascular Pericytes Following Ischemia Have Multipotential Stem Cell Activity to Differentiate Into Neural and Vascular Lineage Cells

(2015) Takayuki Nakagomi et al.   STEM CELLS

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

Microglial and macrophage polarization—new prospects for brain repair

(2014) Xiaoming Hu et al.   Nature Reviews Neurology

Astrocytic laminin regulates pericyte differentiation and maintains blood brain barrier integrity

(2014) Yao Yao et al.   Nature Communications

Blood–brain barrier structure and function and the challenges for CNS drug delivery

(2013) N. Joan Abbott   JOURNAL OF INHERITED METABOLIC DISEASE

Role of the extracellular matrix in regulating stem cell fate

(2013) Fiona M. Watt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

PDGF Receptor β Signaling in Pericytes Following Ischemic Brain Injury

(2012) Koichi Arimura et al.   CURRENT NEUROVASCULAR RESEARCH

Neurotrophin production in brain pericytes during hypoxia: A role of pericytes for neuroprotection

(2012) Koji Ishitsuka et al.   MICROVASCULAR RESEARCH

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Proteinuria and clinical outcomes after ischemic stroke

(2012) Y. Kumai et al.   NEUROLOGY

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

Extracellular matrix and matrix receptors in blood-brain barrier formation and stroke

(2011) Kim M. Baeten et al.   Developmental Neurobiology

PDGFR-β as a Positive Regulator of Tissue Repair in a Mouse Model of Focal Cerebral Ischemia

(2011) Jie Shen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Perlecan domain V is neuroprotective and proangiogenic following ischemic stroke in rodents

(2011) Boyeon Lee et al.   JOURNAL OF CLINICAL INVESTIGATION

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

Ischemia-Induced Neural Stem/Progenitor Cells in the Pia Mater Following Cortical Infarction

(2011) Takayuki Nakagomi et al.   STEM CELLS AND DEVELOPMENT

Prestroke Glycemic Control Is Associated With the Functional Outcome in Acute Ischemic Stroke

(2011) Masahiro Kamouchi et al.   STROKE

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Activation of PDGF-CC by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke

(2008) Enming J Su et al.   NATURE MEDICINE

The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

(2008) Berislav V. Zlokovic   NEURON