AIM/CD5L attenuates DAMPs in the injured brain and thereby ameliorates ischemic stroke

Use of DAMPs and SAMPs as Therapeutic Targets or Therapeutics: A Note of Caution

(2020) Walter Gottlieb Land   Molecular Diagnosis & Therapy

Large-Vessel Stroke as a Presenting Feature of Covid-19 in the Young

(2020) Thomas J. Oxley et al.   NEW ENGLAND JOURNAL OF MEDICINE

COVID-19 and ischemic stroke: a systematic review and meta-summary of the literature

(2020) Ying-Kiat Tan et al.   JOURNAL OF THROMBOSIS AND THROMBOLYSIS

Selenium Drives a Transcriptional Adaptive Program to Block Ferroptosis and Treat Stroke

(2019) Ishraq Alim et al.   CELL

DAMPs, PAMPs, and LAMPs in Immunity and Sterile Inflammation

(2019) Joel Zindel et al.   Annual Review of Pathology-Mechanisms of Disease

Targeting RAGE Signaling in Inflammatory Disease

(2018) Barry I. Hudson et al.   Annual Review of Medicine

MAFB is dispensable for the fetal testis morphogenesis and the maintenance of spermatogenesis in adult mice

(2018) Hossam H. Shawki et al.   PLoS One

A scavenging system against internal pathogens promoted by the circulating protein apoptosis inhibitor of macrophage (AIM)

(2018) Satoko Arai et al.   Seminars in Immunopathology

The IgM pentamer is an asymmetric pentagon with an open groove that binds the AIM protein

(2018) Emiri Hiramoto et al.   Science Advances

Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations

(2017) Qiang Liu et al.   IMMUNITY

Activation of apoptosis inhibitor of macrophage is a sensitive diagnostic marker for NASH-associated hepatocellular carcinoma

(2017) Noriyuki Koyama et al.   JOURNAL OF GASTROENTEROLOGY

MAFB prevents excess inflammation after ischemic stroke by accelerating clearance of damage signals through MSR1

(2017) Takashi Shichita et al.   NATURE MEDICINE

Apoptosis inhibitor of macrophage ameliorates fungus-induced peritoneal injury model in mice

(2017) Takako Tomita et al.   Scientific Reports

Neuroprotection in acute stroke: targeting excitotoxicity, oxidative and nitrosative stress, and inflammation

(2016) Ángel Chamorro et al.   LANCET NEUROLOGY

Apoptosis inhibitor of macrophage protein enhances intraluminal debris clearance and ameliorates acute kidney injury in mice

(2016) Satoko Arai et al.   NATURE MEDICINE

Overexpression of caveolin-1 attenuates brain edema by inhibiting tight junction degradation

(2016) Kang-Ho Choi et al.   Oncotarget

Impact of feline AIM on the susceptibility of cats to renal disease

(2016) Ryoichi Sugisawa et al.   Scientific Reports

A proteolytic modification of AIM promotes its renal excretion

(2016) Tomoko Yamazaki et al.   Scientific Reports

Diagnostic performance of peroxiredoxin 1 to determine time-of-onset of acute cerebral infarction

(2016) Sébastien Richard et al.   Scientific Reports

CD5L/AIM Regulates Lipid Biosynthesis and Restrains Th17 Cell Pathogenicity

(2015) Chao Wang et al.   CELL

Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke

(2015) M. Kawabori et al.   JOURNAL OF NEUROSCIENCE

Electroacupuncture pretreatment attenuates blood-brain barrier disruption following cerebral ischemia/reperfusion

(2015) RONG ZOU et al.   Molecular Medicine Reports

Natural antibodies as a sensor of electronegative damage-associated molecular patterns (DAMPs)

(2014) Koji Uchida   FREE RADICAL BIOLOGY AND MEDICINE

Stepwise Recruitment of Transcellular and Paracellular Pathways Underlies Blood-Brain Barrier Breakdown in Stroke

(2014) Daniel Knowland et al.   NEURON

Circulating AIM as an Indicator of Liver Damage and Hepatocellular Carcinoma in Humans

(2014) Tomoko Yamazaki et al.   PLoS One

MafB promotes atherosclerosis by inhibiting foam-cell apoptosis

(2014) Michito Hamada et al.   Nature Communications

Circulating AIM Prevents Hepatocellular Carcinoma through Complement Activation

(2014) Natsumi Maehara et al.   Cell Reports

Differentiated kidney epithelial cells repair injured proximal tubule

(2013) T. Kusaba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity-Associated Autoantibody Production Requires AIM to Retain the Immunoglobulin M Immune Complex on Follicular Dendritic Cells

(2013) Satoko Arai et al.   Cell Reports

Recognition of bacterial infection by innate immune sensors

(2012) Sushil Kumar et al.   CRITICAL REVIEWS IN MICROBIOLOGY

Peroxiredoxin family proteins are key initiators of post-ischemic inflammation in the brain

(2012) Takashi Shichita et al.   NATURE MEDICINE

Cellular pathophysiology of ischemic acute kidney injury

(2011) Joseph V. Bonventre et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene expression differences between stroke-associated and asymptomatic carotid plaques

(2011) Jani Saksi et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Repertoire of microglial and macrophage responses after spinal cord injury

(2011) Samuel David et al.   NATURE REVIEWS NEUROSCIENCE

Biphasic actions of HMGB1 signaling in inflammation and recovery after stroke

(2010) Kazuhide Hayakawa et al.   Annals of the New York Academy of Sciences

Macrophage-Derived AIM Is Endocytosed into Adipocytes and Decreases Lipid Droplets via Inhibition of Fatty Acid Synthase Activity

(2010) Jun Kurokawa et al.   Cell Metabolism

Brain Extracellular Fluid Protein Changes in Acute Stroke Patients

(2010) Loïc Dayon et al.   JOURNAL OF PROTEOME RESEARCH

Peroxiredoxin: a central player in immune modulation

(2010) M. W. ROBINSON et al.   PARASITE IMMUNOLOGY

Mrp-8 and -14 mediate CNS injury in focal cerebral ischemia

(2009) Gina Ziegler et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Peroxiredoxin 1 Stimulates Secretion of Proinflammatory Cytokines by Binding to TLR4

(2009) J. R. Riddell et al.   JOURNAL OF IMMUNOLOGY

Intrinsic Epithelial Cells Repair the Kidney after Injury

(2008) Benjamin D. Humphreys et al.   Cell Stem Cell

Origin and physiological roles of inflammation

(2008) Ruslan Medzhitov   NATURE