Pericyte degeneration causes white matter dysfunction in the mouse central nervous system

Differing associations between Aβ accumulation, hypoperfusion, blood–brain barrier dysfunction and loss of PDGFRB pericyte marker in the precuneus and parietal white matter in Alzheimer's disease

(2017) J Scott Miners et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Plasminogen Deficiency Delays the Onset and Protects from Demyelination and Paralysis in Autoimmune Neuroinflammatory Disease

(2017) Maureen A. Shaw et al.   JOURNAL OF NEUROSCIENCE

Pericyte degeneration leads to neurovascular uncoupling and limits oxygen supply to brain

(2017) Kassandra Kisler et al.   NATURE NEUROSCIENCE

Pericytes Stimulate Oligodendrocyte Progenitor Cell Differentiation during CNS Remyelination

(2017) Alerie Guzman De La Fuente et al.   Cell Reports

Regional early and progressive loss of brain pericytes but not vascular smooth muscle cells in adult mice with disrupted platelet-derived growth factor receptor-β signaling

(2017) Angeliki Maria Nikolakopoulou et al.   PLoS One

White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the dominantly inherited Alzheimer network

(2016) Seonjoo Lee et al.   ANNALS OF NEUROLOGY

Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy

(2016) Qiming Liang et al.   Cell Stem Cell

The superficial white matter in Alzheimer's disease

(2016) Owen R Phillips et al.   HUMAN BRAIN MAPPING

Relation of cerebral vessel disease to Alzheimer's disease dementia and cognitive function in elderly people: a cross-sectional study

(2016) Zoe Arvanitakis et al.   LANCET NEUROLOGY

Astrocytes mediate neurovascular signaling to capillary pericytes but not to arterioles

(2016) Anusha Mishra et al.   NATURE NEUROSCIENCE

Pericytes of the neurovascular unit: key functions and signaling pathways

(2016) Melanie D Sweeney et al.   NATURE NEUROSCIENCE

Vascular contributions to cognitive impairment and dementia including Alzheimer's disease

(2015) Heather M. Snyder et al.   Alzheimers & Dementia

Pericytes are involved in the pathogenesis of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

(2015) Mitrajit Ghosh et al.   ANNALS OF NEUROLOGY

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

CNS Myelin Wrapping Is Driven by Actin Disassembly

(2015) J. Bradley Zuchero et al.   DEVELOPMENTAL CELL

Relationship between white matter lesions and regional cerebral blood flow changes during longitudinal follow up in Alzheimer's disease

(2015) Takuya Hanaoka et al.   Geriatrics & Gerontology International

What is a pericyte?

(2015) David Attwell et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Synthesis of Improved Lysomotropic Autophagy Inhibitors

(2015) Tong Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel Overgrowth Syndrome Phenotype Due to Recurrent De Novo PDGFRB Mutation

(2015) Toshiki Takenouchi et al.   JOURNAL OF PEDIATRICS

GLUT1 reductions exacerbate Alzheimer's disease vasculo-neuronal dysfunction and degeneration

(2015) Ethan A Winkler et al.   NATURE NEUROSCIENCE

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance

(2015) Zhen Zhao et al.   NATURE NEUROSCIENCE

Knocking down disease: a progress report on siRNA therapeutics

(2015) Anders Wittrup et al.   NATURE REVIEWS GENETICS

Fibrin deposited in the Alzheimer's disease brain promotes neuronal degeneration

(2015) Marta Cortes-Canteli et al.   NEUROBIOLOGY OF AGING

Blood-Brain Barrier Breakdown in the Aging Human Hippocampus

(2015) Axel Montagne et al.   NEURON

Stroke and Potentially Preventable Dementias Proclamation

(2015) Vladimir Hachinski   STROKE

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

(2015) Jae Kyu Ryu et al.   Nature Communications

ROCKETSHIP: a flexible and modular software tool for the planning, processing and analysis of dynamic MRI studies

(2015) Samuel R. Barnes et al.   BMC MEDICAL IMAGING

Neural Networks of the Mouse Neocortex

(2014) Brian Zingg et al.   CELL

Capillary pericytes regulate cerebral blood flow in health and disease

(2014) Catherine N. Hall et al.   NATURE

NLRP3 inflammasome contributes to inflammation after intracerebral hemorrhage

(2013) Qingyi Ma et al.   ANNALS OF NEUROLOGY

Enlarged Perivascular Spaces and Cerebral Small Vessel Disease

(2013) Gillian M. Potter et al.   International Journal of Stroke

Signaling through ERK1/2 Controls Myelin Thickness during Myelin Repair in the Adult Central Nervous System

(2013) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Aprotinin, but not ε-aminocaproic acid and tranexamic acid, exerts neuroprotection against excitotoxic injury in an in vitro neuronal cell culture model

(2013) Zhaohui Lu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration

(2013) Joanna M Wardlaw et al.   LANCET NEUROLOGY

The Pathobiology of Vascular Dementia

(2013) Costantino Iadecola   NEURON

Age-Dependent Exacerbation of White Matter Stroke Outcomes

(2013) Shira Rosenzweig et al.   STROKE

Caspase Functions in Cell Death and Disease

(2013) D. R. McIlwain et al.   Cold Spring Harbor Perspectives in Biology

Pericyte loss influences Alzheimer-like neurodegeneration in mice

(2013) Abhay P. Sagare et al.   Nature Communications

Deficiency in Mural Vascular Cells Coincides with Blood-Brain Barrier Disruption in Alzheimer's Disease

(2012) Jesse D. Sengillo et al.   BRAIN PATHOLOGY

Dynamic changes in myelin aberrations and oligodendrocyte generation in chronic amyloidosis in mice and men

(2012) Gwendolyn Behrendt et al.   GLIA

The vascular factor in Alzheimer's disease: A study in Golgi technique and electron microscopy

(2012) Stavros J. Baloyannis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Apolipoprotein E controls cerebrovascular integrity via cyclophilin A

(2012) Robert D. Bell et al.   NATURE

Inhibitory Effect of mTOR Activator MHY1485 on Autophagy: Suppression of Lysosomal Fusion

(2012) Yeon Ja Choi et al.   PLoS One

Metabolic Stress in Autophagy and Cell Death Pathways

(2012) B. J. Altman et al.   Cold Spring Harbor Perspectives in Biology

Genetically Induced Adult Oligodendrocyte Cell Death Is Associated with Poor Myelin Clearance, Reduced Remyelination, and Axonal Damage

(2011) H. B. F. Pohl et al.   JOURNAL OF NEUROSCIENCE

Ancrod and Fibrin Formation

(2011) Shuo Liu et al.   STROKE

Effect of Hypoxia/Reoxygenation on Cell Viability and Expression and Secretion of Neurotrophic Factors (NTFs) in Primary Cultured Schwann Cells

(2010) Hao Zhu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

Methods in Mammalian Autophagy Research

(2010) Noboru Mizushima et al.   CELL

Fibrinogen Triggers Astrocyte Scar Formation by Promoting the Availability of Active TGF-  after Vascular Damage

(2010) C. Schachtrup et al.   JOURNAL OF NEUROSCIENCE

Pericyte-specific expression of PDGF beta receptor in mouse models with normal and deficient PDGF beta receptor signaling

(2010) Ethan A Winkler et al.   Molecular Neurodegeneration

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Pericytes are required for blood–brain barrier integrity during embryogenesis

(2010) Richard Daneman et al.   NATURE

Fibrinogen and β-Amyloid Association Alters Thrombosis and Fibrinolysis: A Possible Contributing Factor to Alzheimer's Disease

(2010) Marta Cortes-Canteli et al.   NEURON

Pericytes Control Key Neurovascular Functions and Neuronal Phenotype in the Adult Brain and during Brain Aging

(2010) Robert D. Bell et al.   NEURON

Cerebral blood flow in ischemic vascular dementia and Alzheimer's disease, measured by arterial spin-labeling magnetic resonance imaging

(2009) Norbert Schuff et al.   Alzheimers & Dementia

Neuroprotective activities of activated protein C mutant with reduced anticoagulant activity

(2009) Huang Guo et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Enrichment of rat oligodendrocyte progenitor cells by magnetic cell sorting

(2009) D. Cizkova et al.   JOURNAL OF NEUROSCIENCE METHODS

Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery

(2009) Muge Yemisci et al.   NATURE MEDICINE

Multiple Sclerosis: An Immune or Neurodegenerative Disorder?

(2008) Bruce D. Trapp et al.   Annual Review of Neuroscience