Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesions

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration

(2021) Cayce E. Dorrier et al.   NATURE NEUROSCIENCE

Brain capillary pericytes exert a substantial but slow influence on blood flow

(2021) David A. Hartmann et al.   NATURE NEUROSCIENCE

Parenchymal pericytes are not the major contributor of extracellular matrix in the fibrotic scar after stroke in male mice

(2019) Michaela Roth et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Fibrotic scar after experimental autoimmune encephalomyelitis inhibits oligodendrocyte differentiation

(2019) Stephanie L. Yahn et al.   NEUROBIOLOGY OF DISEASE

Reducing Pericyte-Derived Scarring Promotes Recovery after Spinal Cord Injury

(2018) David Oliveira Dias et al.   CELL

Injury type-dependent differentiation of NG2 glia into heterogeneous astrocytes

(2018) Amber R. Hackett et al.   EXPERIMENTAL NEUROLOGY

Fibrotic scarring following lesions to the central nervous system

(2018) David Oliveira Dias et al.   MATRIX BIOLOGY

A molecular atlas of cell types and zonation in the brain vasculature

(2018) Michael Vanlandewijck et al.   NATURE

The dynamics of revascularization after white matter infarction monitored in Flt1-tdsRed and Flk1-GFP mice

(2018) Hiroya Shimauchi-Ohtaki et al.   NEUROSCIENCE LETTERS

PDGFR-β-Positive Perivascular Adventitial Cells Expressing Nestin Contribute to Fibrotic Scar Formation in the Striatum of 3-NP Intoxicated Rats

(2018) Tae-Ryong Riew et al.   Frontiers in Molecular Neuroscience

Cell biology of spinal cord injury and repair

(2017) Timothy M. O’Shea et al.   JOURNAL OF CLINICAL INVESTIGATION

Proliferating NG2-Cell-Dependent Angiogenesis and Scar Formation Alter Axon Growth and Functional Recovery After Spinal Cord Injury in Mice

(2017) Zoe C. Hesp et al.   JOURNAL OF NEUROSCIENCE

Dynamic Changes in Brain Mesenchymal Perivascular Cells Associate with Multiple Sclerosis Disease Duration, Active Inflammation, and Demyelination

(2017) Ellen Iacobaeus et al.   Stem Cells Translational Medicine

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Col1a1+ perivascular cells in the brain are a source of retinoic acid following stroke

(2016) Kathleen K. Kelly et al.   BMC NEUROSCIENCE

Factors determining the density of AQP4 water channel molecules at the brain–blood interface

(2016) Eystein Hellstrøm Hoddevik et al.   Brain Structure & Function

Normalization of Tumor Vessels by Tie2 Activation and Ang2 Inhibition Enhances Drug Delivery and Produces a Favorable Tumor Microenvironment

(2016) Jin-Sung Park et al.   CANCER CELL

Tamoxifen in the Mouse Brain: Implications for Fate-Mapping Studies Using the Tamoxifen-Inducible Cre-loxP System

(2016) Martin Valny et al.   Frontiers in Cellular Neuroscience

Understanding the NG2 Glial Scar after Spinal Cord Injury

(2016) Amber R. Hackett et al.   Frontiers in Neurology

Perivascular Gli1+ Progenitors Are Key Contributors to Injury-Induced Organ Fibrosis

(2015) Rafael Kramann et al.   Cell Stem Cell

Systemic administration of epothilone B promotes axon regeneration after spinal cord injury

(2015) J. Ruschel et al.   SCIENCE

Functional regeneration beyond the glial scar

(2014) Jared M. Cregg et al.   EXPERIMENTAL NEUROLOGY

A latent neurogenic program in astrocytes regulated by Notch signaling in the mouse

(2014) J. P. Magnusson et al.   SCIENCE

IL-10 Deficiency Exacerbates the Brain Inflammatory Response to Permanent Ischemia without Preventing Resolution of the Lesion

(2013) Isabel Pérez-de Puig et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Short Hairpin RNA against PTEN Enhances Regenerative Growth of Corticospinal Tract Axons after Spinal Cord Injury

(2013) K. Zukor et al.   JOURNAL OF NEUROSCIENCE

Perivascular Fibroblasts Form the Fibrotic Scar after Contusive Spinal Cord Injury

(2013) C. Soderblom et al.   JOURNAL OF NEUROSCIENCE

Resident Neural Stem Cells Restrict Tissue Damage and Neuronal Loss After Spinal Cord Injury in Mice

(2013) H. Sabelstrom et al.   SCIENCE

Early Loss of Pericytes and Perivascular Stromal Cell-Induced Scar Formation after Stroke

(2012) Francisco Fernández-Klett et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Disruption of NMDA Receptors in Oligodendroglial Lineage Cells Does Not Alter Their Susceptibility to Experimental Autoimmune Encephalomyelitis or Their Normal Development

(2012) F. Guo et al.   JOURNAL OF NEUROSCIENCE

Lineage tracing and genetic ablation of ADAM12+ perivascular cells identify a major source of profibrotic cells during acute tissue injury

(2012) Sophie Dulauroy et al.   NATURE MEDICINE

Inhibition of soluble tumour necrosis factor is therapeutic in experimental autoimmune encephalomyelitis and promotes axon preservation and remyelination

(2011) Roberta Brambilla et al.   BRAIN

NG2 expression in glioblastoma identifies an actively proliferating population with an aggressive molecular signature

(2011) M. T. F. Al-Mayhani et al.   NEURO-ONCOLOGY

A Pericyte Origin of Spinal Cord Scar Tissue

(2011) C. Goritz et al.   SCIENCE

Origin of New Glial Cells in Intact and Injured Adult Spinal Cord

(2010) Fanie Barnabé-Heider et al.   Cell Stem Cell

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

(2010) Matthias Drosten et al.   EMBO JOURNAL

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

PTEN deletion enhances the regenerative ability of adult corticospinal neurons

(2010) Kai Liu et al.   NATURE NEUROSCIENCE

Fate Tracing Reveals the Pericyte and Not Epithelial Origin of Myofibroblasts in Kidney Fibrosis

(2009) Benjamin D. Humphreys et al.   AMERICAN JOURNAL OF PATHOLOGY

Initiation and Progression of Axonopathy in Experimental Autoimmune Encephalomyelitis

(2009) A. M. Soulika et al.   JOURNAL OF NEUROSCIENCE

A robust and high-throughput Cre reporting and characterization system for the whole mouse brain

(2009) Linda Madisen et al.   NATURE NEUROSCIENCE

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

(2008) A. Buffo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spinal Cord Injury Reveals Multilineage Differentiation of Ependymal Cells

(2008) Konstantinos Meletis et al.   PLOS BIOLOGY