IL-27p28 specifically regulates MHC II expression in macrophages through CIITA

CD11c+ macrophages are proangiogenic and necessary for experimental choroidal neovascularization

(2023) Steven Droho et al.   JCI Insight

The inflammatory response induced by Pseudomonas aeruginosa in macrophages enhances apoptotic cell removal

(2021) Adriana Valeria Jäger et al.   Scientific Reports

Decoding the Role of Interleukin-30 in the Crosstalk Between Cancer and Myeloid Cells

(2020) Emma Di Carlo   Cells

Immunodominant Mycobacterium tuberculosis Protein Rv1507A Elicits Th1 Response and Modulates Host Macrophage Effector Functions

(2020) Simran Kaur Arora et al.   Frontiers in Immunology

HSP70-Homolog DnaK of Pseudomonas aeruginosa Increases the Production of IL-27 through Expression of EBI3 via TLR4-Dependent NF-κB and TLR4-Independent Akt Signaling

(2020) Jisu Jeon et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5

(2018) Maria Buxadé et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Immunobiology of Interleukin-27

(2015) Hiroki Yoshida et al.   Annual Review of Immunology

The presence of interleukin-27 during monocyte-derived dendritic cell differentiation promotes improved antigen processing and stimulation of T cells

(2015) Joo-Yong Jung et al.   IMMUNOLOGY

CD4:CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV-positive patients

(2015) Wei Lu et al.   Journal of the International AIDS Society

IL-12 and IL-27 regulate the phagolysosomal pathway in mycobacteria-infected human macrophages

(2014) Joo-Yong Jung et al.   Cell Communication and Signaling

IL-27 controls sepsis-induced impairment of lung antibacterial host defence

(2014) Ju Cao et al.   THORAX

Macrophage biology in development, homeostasis and disease

(2013) Thomas A. Wynn et al.   NATURE

Interleukin-27 Receptor Limits Atherosclerosis in Ldlr −/− Mice

(2012) Ekaterina K. Koltsova et al.   CIRCULATION RESEARCH

High susceptibility to liver injury in IL-27 p28 conditional knockout mice involves intrinsic interferon-γ dysregulation of CD4+T cells

(2012) Song Zhang et al.   HEPATOLOGY

A Role for IL-27 in Limiting T Regulatory Cell Populations

(2011) E. D. Tait Wojno et al.   JOURNAL OF IMMUNOLOGY

PU.1 Binds to a Distal Regulatory Element That Is Necessary for B Cell-Specific Expression of CIITA

(2010) H. Yoon et al.   JOURNAL OF IMMUNOLOGY

Regulation of the class II and class I MHC pathways in human THP-1 monocytic cells by interleukin-27

(2008) Xiao Ming Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS