Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5

NFAT5-Regulated Macrophage Polarization Supports the Proinflammatory Function of Macrophages and T Lymphocytes

(2017) Mónica Tellechea et al.   JOURNAL OF IMMUNOLOGY

Multi-tiered Reorganization of the Genome during B Cell Affinity Maturation Anchored by a Germinal Center-Specific Locus Control Region

(2016) Karen L. Bunting et al.   IMMUNITY

Context-dependent regulation of Th17-associated genes and IFNγ expression by the transcription factor NFAT5

(2016) Maria Alberdi et al.   IMMUNOLOGY AND CELL BIOLOGY

Lineage-specific enhancers activate self-renewal genes in macrophages and embryonic stem cells

(2016) E. L. Soucie et al.   SCIENCE

Cutaneous Na+ Storage Strengthens the Antimicrobial Barrier Function of the Skin and Boosts Macrophage-Driven Host Defense

(2015) Jonathan Jantsch et al.   Cell Metabolism

Immunodeficiency and Autoimmune Enterocolopathy Linked to NFAT5 Haploinsufficiency

(2015) Brigid S. Boland et al.   JOURNAL OF IMMUNOLOGY

Common distal elements orchestrate CIITA isoform-specific expression in multiple cell types

(2014) S Lohsen et al.   GENES AND IMMUNITY

Interleukin-10 Receptor Signaling in Innate Immune Cells Regulates Mucosal Immune Tolerance and Anti-Inflammatory Macrophage Function

(2014) Dror S. Shouval et al.   IMMUNITY

Constant replenishment from circulating monocytes maintains the macrophage pool in the intestine of adult mice

(2014) Calum C Bain et al.   NATURE IMMUNOLOGY

The NLRP3 inflammasome is released as a particulate danger signal that amplifies the inflammatory response

(2014) Alberto Baroja-Mazo et al.   NATURE IMMUNOLOGY

An MHC II-Dependent Activation Loop between Adipose Tissue Macrophages and CD4+ T Cells Controls Obesity-Induced Inflammation

(2014) Kae Won Cho et al.   Cell Reports

Adipose Tissue Macrophages Function As Antigen-Presenting Cells and Regulate Adipose Tissue CD4 + T Cells in Mice

(2013) David L. Morris et al.   DIABETES

Lung-resident tissue macrophages generate Foxp3+regulatory T cells and promote airway tolerance

(2013) Pejman Soroosh et al.   JOURNAL OF EXPERIMENTAL MEDICINE

NFAT5 induction by the pre-T-cell receptor serves as a selective survival signal in T-lymphocyte development

(2013) R. Berga-Bolanos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation

(2012) O. Hakim et al.   GENOME RESEARCH

Gene expression induced by Toll-like receptors in macrophages requires the transcription factor NFAT5

(2012) Maria Buxadé et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Global changes in the nuclear positioning of genes and intra- and interdomain genomic interactions that orchestrate B cell fate

(2012) Yin C Lin et al.   NATURE IMMUNOLOGY

Transcription initiation platforms and GTF recruitment at tissue-specific enhancers and promoters

(2011) Frederic Koch et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

NFAT5 Regulates T Lymphocyte Homeostasis and CD24-Dependent T Cell Expansion under Pathologic Hypernatremia

(2010) R. Berga-Bolanos et al.   JOURNAL OF IMMUNOLOGY

PU.1 Binds to a Distal Regulatory Element That Is Necessary for B Cell-Specific Expression of CIITA

(2010) H. Yoon et al.   JOURNAL OF IMMUNOLOGY

Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm

(2010) Subhra K Biswas et al.   NATURE IMMUNOLOGY

Histone H3K27ac separates active from poised enhancers and predicts developmental state

(2010) M. P. Creyghton et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CBP-mediated acetylation of histone H3 lysine 27 antagonizes Drosophila Polycomb silencing

(2009) F. Tie et al.   DEVELOPMENT

Immunological synapse formation inhibits, via NF-κB and FOXO1, the apoptosis of dendritic cells

(2009) Lorena Riol-Blanco et al.   NATURE IMMUNOLOGY

The chromatin-remodeling enzyme BRG1 coordinates CIITA induction through many interdependent distal enhancers

(2008) Zuyao Ni et al.   NATURE IMMUNOLOGY