IL-27 controls sepsis-induced impairment of lung antibacterial host defence

Immunotherapy for the Adjunctive Treatment of Sepsis: From Immunosuppression to Immunostimulation. Time for a Paradigm Change?

(2013) Jenneke Leentjens et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis

(2013) Jesmond Dalli et al.   EMBO Molecular Medicine

B and T lymphocyte attenuator inhibits LPS-induced endotoxic shock by suppressing Toll-like receptor 4 signaling in innate immune cells

(2013) Y. Kobayashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human TCRγδ+T cells represent a novel target for IL-27 activity

(2012) Fabio Morandi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Production of interleukin-27 by human neutrophils regulates their function during bacterial infection

(2012) Darawan Rinchai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-27: Balancing Protective and Pathological Immunity

(2012) Christopher A. Hunter et al.   IMMUNITY

IFN-  Limits Th9-Mediated Autoimmune Inflammation through Dendritic Cell Modulation of IL-27

(2012) G. Murugaiyan et al.   JOURNAL OF IMMUNOLOGY

Toll-Like Receptor 2 Deficiency Increases Resistance to Pseudomonas aeruginosa Pneumonia in the Setting of Sepsis-Induced Immune Dysfunction

(2012) Frédéric Pène et al.   JOURNAL OF INFECTIOUS DISEASES

For sepsis, the drugs don't work

(2012) The Lancet Infectious Diseases   LANCET INFECTIOUS DISEASES

Dose-Dependent Effect of Anti-CTLA-4 on Survival in Sepsis

(2011) Shigeaki Inoue et al.   SHOCK

IL-6 Promotes NK Cell Production of IL-17 during Toxoplasmosis

(2010) Sara T. Passos et al.   JOURNAL OF IMMUNOLOGY

A Role for IL-1 Receptor-Associated Kinase-M in Prostaglandin E2-Induced Immunosuppression Post-Bone Marrow Transplantation

(2010) L. L. N. Hubbard et al.   JOURNAL OF IMMUNOLOGY

Lipopolysaccharide-Mediated IL-10 Transcriptional Regulation Requires Sequential Induction of Type I IFNs and IL-27 in Macrophages

(2010) S. S. Iyer et al.   JOURNAL OF IMMUNOLOGY

Delayed administration of anti-PD-1 antibody reverses immune dysfunction and improves survival during sepsis

(2010) P. Brahmamdam et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Immunotherapy for Sepsis — A New Approach against an Ancient Foe

(2010) Richard S. Hotchkiss et al.   NEW ENGLAND JOURNAL OF MEDICINE

Epilysin (MMP-28) Restrains Early Macrophage Recruitment in Pseudomonas aeruginosa Pneumonia

(2009) A. M. Manicone et al.   JOURNAL OF IMMUNOLOGY

The sepsis seesaw: tilting toward immunosuppression

(2009) Richard S Hotchkiss et al.   NATURE MEDICINE