Circ-CARD6 inhibits oxidative stress-induced apoptosis and autophagy in ARPE-19 cells via the miR-29b-3p/PRDX6/PI3K/Akt axis

EWSR1-induced circNEIL3 promotes glioma progression and exosome-mediated macrophage immunosuppressive polarization via stabilizing IGF2BP3

(2022) Ziwen Pan et al.   Molecular Cancer

Inhibition of cGAS-STING by JQ1 alleviates oxidative stress-induced retina inflammation and degeneration

(2022) Ming Zou et al.   CELL DEATH AND DIFFERENTIATION

Chlorogenic Acid Prevents Microglia-Induced Neuronal Apoptosis and Oxidative Stress under Hypoxia-Ischemia Environment by Regulating the MIR497HG/miR-29b-3p/SIRT1 Axis

(2022) Yong Fan et al.   DISEASE MARKERS

Retinal Circular RNA hsa_circ_0087207 Expression Promotes Apoptotic Cell Death in Induced Pluripotent Stem Cell-Derived Leber’s Hereditary Optic Neuropathy-like Models

(2022) Yi-Ping Yang et al.   Biomedicines

Oxidative stress‐induced lncRNA CYLD‐AS1 promotes RPE inflammation via Nrf2/ miR ‐134‐5p/ NF‐κB signaling pathway

(2022) Han Du et al.   FASEB JOURNAL

Regulation of oxidative stress and inflammatory responses in human retinal pigment epithelial cells

(2022) Niina Harju   ACTA OPHTHALMOLOGICA

MiR-29b-3p aggravates cardiac hypoxia/reoxygenation injury via targeting PTX3

(2021) Dan He et al.   CYTOTECHNOLOGY

Changes in Visual Function and Correlations with Inner Retinal Structure in Acute and Chronic Leber’s Hereditary Optic Neuropathy Patients after Treatment with Idebenone

(2021) Berthold Pemp et al.   Journal of Clinical Medicine

Targeting choroidal vascular dysfunction via inhibition of circRNA-FoxO1 for prevention and management of myopic pathology

(2021) Dan Li et al.   MOLECULAR THERAPY

Circular RNA circZNF292 regulates H 2 O 2 ‐induced injury in human lens epithelial HLE‐B3 cells depending on the regulation of the miR‐222‐3p/E2F3 axis

(2021) Xinyan Xu et al.   CELL BIOLOGY INTERNATIONAL

Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function

(2021) Congcong Wang et al.   VIROLOGICA SINICA

MiR-29b-3p promotes particulate matter-induced inflammatory responses by regulating the C1QTNF6/AMPK pathway

(2020) Jian Wang et al.   Aging-US

Tribulus terrestris Ameliorates Oxidative Stress-Induced ARPE-19 Cell Injury through the PI3K/Akt-Nrf2 Signaling Pathway

(2020) Zhenli Yuan et al.   Oxidative Medicine and Cellular Longevity

miR-122 promotes diabetic retinopathy through targeting TIMP3

(2020) Mingliang Wang et al.   Animal Cells and Systems

Mitophagy in degenerative joint diseases

(2020) Kai Sun et al.   Autophagy

Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

(2020) Trine Line Hauge Okholm et al.   Genome Medicine

Retinal miRNA Functions in Health and Disease

(2019) Marta Zuzic et al.   Genes

Mitochondrial oxidative stress in the retinal pigment epithelium (RPE) led to metabolic dysfunction in both the RPE and retinal photoreceptors

(2019) Emily E. Brown et al.   Redox Biology

Inhibiting microRNA-144 potentiates Nrf2-dependent antioxidant signaling in RPE and protects against oxidative stress-induced outer retinal degeneration

(2019) Ravirajsinh N. Jadeja et al.   Redox Biology

Glutathione depletion induces ferroptosis, autophagy, and premature cell senescence in retinal pigment epithelial cells

(2018) Yun Sun et al.   Cell Death & Disease

Oxidative stress induces ferroptotic cell death in retinal pigment epithelial cells

(2018) Kiyohito Totsuka et al.   EXPERIMENTAL EYE RESEARCH

Leber's hereditary optic neuropathy caused by a mutation in mitochondrial tRNA Thr in eight Chinese pedigrees

(2017) Juanjuan Zhang et al.   MITOCHONDRION

Peroxiredoxin 6 Is a Crucial Factor in the Initial Step of Mitochondrial Clearance and Is Upstream of the PINK1-Parkin Pathway

(2016) Shuaipeng Ma et al.   ANTIOXIDANTS & REDOX SIGNALING

Molecular findings from 537 individuals with inherited retinal disease

(2016) Jamie M Ellingford et al.   JOURNAL OF MEDICAL GENETICS

PRDX6 Protects ARPE-19 Cells from Oxidative Damage via PI3K/AKT Signaling

(2015) Xu Zha et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Molecular targets for cancer therapy in the PI3K/AKT/mTOR pathway

(2013) Jiri Polivka et al.   PHARMACOLOGY & THERAPEUTICS

A novel deletion in the GTPase domain of OPA1 causes defects in mitochondrial morphology and distribution, but not in function

(2008) Marco Spinazzi et al.   HUMAN MOLECULAR GENETICS