Retinal Circular RNA hsa_circ_0087207 Expression Promotes Apoptotic Cell Death in Induced Pluripotent Stem Cell-Derived Leber’s Hereditary Optic Neuropathy-like Models

Changes in Visual Function and Correlations with Inner Retinal Structure in Acute and Chronic Leber’s Hereditary Optic Neuropathy Patients after Treatment with Idebenone

(2021) Berthold Pemp et al.   Journal of Clinical Medicine

Circular RNA CircPPP1CB Suppresses Tumorigenesis by Interacting With the MiR-1307-3p/SMG1 Axis in Human Bladder Cancer

(2021) Feifan Wang et al.   Frontiers in Cell and Developmental Biology

Involvement of endoplasmic reticulum stress in rotenone-induced leber hereditary optic neuropathy model and the discovery of new therapeutic agents

(2021) Yakumo Aoyama et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Circular RNA_0000326 promotes bladder cancer progression via microRNA-338-3p/ETS Proto-Oncogene 1/phosphoinositide-3 kinase/Akt pathway

(2021) Yong Chen et al.   Bioengineered

Mitochondrial transport mediates survival of retinal ganglion cells in affected LHON patients

(2020) Tien-Chun Yang et al.   HUMAN MOLECULAR GENETICS

CircRNA CircRIMS Acts as a MicroRNA Sponge to Promote Gastric Cancer Metastasis

(2020) Jun Lin et al.   ACS Omega

CircRNA hsa_circRNA_104348 promotes hepatocellular carcinoma progression through modulating miR-187-3p/RTKN2 axis and activating Wnt/β-catenin pathway

(2020) Guanqun Huang et al.   Cell Death & Disease

Circular RNA circNRIP1 acts as a microRNA-149-5p sponge to promote gastric cancer progression via the AKT1/mTOR pathway

(2019) Xing Zhang et al.   Molecular Cancer

The Progress of Gene Therapy for Leber's Optic Hereditary Neuropathy

(2018) Yong Zhang et al.   CURRENT GENE THERAPY

Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy

(2018) You-Ren Wu et al.   EXPERIMENTAL CELL RESEARCH

The Biogenesis, Functions, and Challenges of Circular RNAs

(2018) Xiang Li et al.   MOLECULAR CELL

Circular RNAs: Promising Biomarkers for Human Diseases

(2018) Zhongrong Zhang et al.   EBioMedicine

Molecular Regulation Mechanisms and Interactions Between Reactive Oxygen Species and Mitophagy

(2018) Pan Fan et al.   DNA AND CELL BIOLOGY

Mitophagy activation repairs Leber’s hereditary optic neuropathy-associated mitochondrial dysfunction and improves cell survival

(2018) Lokendra Kumar Sharma et al.   HUMAN MOLECULAR GENETICS

Inherited eye-related disorders due to mitochondrial dysfunction

(2017) Patrick Yu-Wai-Man et al.   HUMAN MOLECULAR GENETICS

Mitochondrial genetics and therapeutic overview of Leber's hereditary optic neuropathy

(2017) Sivasamy Ramasamy et al.   INDIAN JOURNAL OF OPHTHALMOLOGY

Circular RNAs in cancer: opportunities and challenges in the field

(2017) L S Kristensen et al.   ONCOGENE

Circular RNAs: analysis, expression and potential functions

(2016) Steven P. Barrett et al.   DEVELOPMENT

Idebenone: A Review in Leber’s Hereditary Optic Neuropathy

(2016) Katherine A. Lyseng-Williamson   DRUGS

Emerging roles and context of circular RNAs

(2016) Amaresh C. Panda et al.   Wiley Interdisciplinary Reviews-RNA

Roles of Circular RNAs in Neurologic Disease

(2016) Yiye Shao et al.   Frontiers in Molecular Neuroscience

Efficacy and Safety of rAAV2-ND4 Treatment for Leber’s Hereditary Optic Neuropathy

(2016) Xing Wan et al.   Scientific Reports

Cigarette toxicity triggers Leber’s hereditary optic neuropathy by affecting mtDNA copy number, oxidative phosphorylation and ROS detoxification pathways

(2015) L Giordano et al.   Cell Death & Disease

Mitochondrial Complex I Deficiency Increases Protein Acetylation and Accelerates Heart Failure

(2013) Georgios Karamanlidis et al.   Cell Metabolism

Idebenone Protects against Retinal Damage and Loss of Vision in a Mouse Model of Leber’s Hereditary Optic Neuropathy

(2012) Fabrice D. Heitz et al.   PLoS One

The dynamic regulation of NAD metabolism in mitochondria

(2012) Liana Roberts Stein et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Idebenone Treatment In Leber's Hereditary Optic Neuropathy

(2011) V. Carelli et al.   BRAIN