m6A-mediated upregulation of miRNA-193a aggravates cardiomyocyte apoptosis and inflammatory response in sepsis-induced cardiomyopathy via the METTL3/ miRNA-193a/BCL2L2 pathway

DNA-PKcs promotes sepsis-induced multiple organ failure by triggering mitochondrial dysfunction

(2022) Rongjun Zou et al.   Journal of Advanced Research

DNA-PKcs interacts with and phosphorylates Fis1 to induce mitochondrial fragmentation in tubular cells during acute kidney injury

(2022) Shiyuan Wang et al.   Science Signaling

Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism

(2022) Ying Tan et al.   Molecular Metabolism

Pathophysiology of sepsis-induced cardiomyopathy

(2021) Steven M. Hollenberg et al.   Nature Reviews Cardiology

LncRNA ZFAS1 plays a role in regulating the inflammatory responses in sepsis-induced acute lung injury via mediating miR-193a-3p

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Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury

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Diagnostic potential of circulating cell‐free microRNAs for community‐acquired pneumonia and pneumonia‐related sepsis

(2020) Stefanie Hermann et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

miRNA-23b as a biomarker of culture-positive neonatal sepsis

(2020) Ahlam Fatmi et al.   MOLECULAR MEDICINE

Overexpression of miR-150-5p Alleviates Apoptosis in Sepsis-Induced Myocardial Depression

(2020) Xiao Geng Zhu et al.   Biomed Research International

N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation

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LDK378 improves micro- and macro-circulation via alleviating STING-mediated inflammatory injury in a Sepsis rat model induced by Cecal ligation and puncture

(2019) Weiwei Ge et al.   Journal of Inflammation-London

METTL3 promote tumor proliferation of bladder cancer by accelerating pri-miR221/222 maturation in m6A-dependent manner

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STING-IRF3 contributes to lipopolysaccharide-induced cardiac dysfunction, inflammation, apoptosis and pyroptosis by activating NLRP3

(2019) Ning Li et al.   Redox Biology

N6-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis

(2019) Daniel A. Kuppers et al.   Nature Communications

Metazoan MicroRNAs

(2018) David P. Bartel   CELL

Septic Cardiomyopathy

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Role of miR-193a in cancer: complexity and factors control the pattern of its expression

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Endothelial microRNAs regulating the NF-κB pathway and cell adhesion molecules during inflammation

(2018) Liang Zhong et al.   FASEB JOURNAL

LncRNA MALAT1 regulates sepsis-induced cardiac inflammation and dysfunction via interaction with miR-125b and p38 MAPK/NFκB

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MicroRNA miR-223 as regulator of innate immunity

(2018) Xiaoyi Yuan et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Lactate as a Potential Biomarker of Sepsis in a Rat Cecal Ligation and Puncture Model

(2018) Xiaozhu Zhai et al.   MEDIATORS OF INFLAMMATION

miRNA-214 Protects Sepsis-Induced Myocardial Injury

(2018) Chen Ge et al.   SHOCK

MicroRNA profile for health risk assessment: Environmental exposure to persistent organic pollutants strongly affects the human blood microRNA machinery

(2017) Julian Krauskopf et al.   Scientific Reports

The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)

(2016) Mervyn Singer et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

MicroRNA-125b Prevents Cardiac Dysfunction in Polymicrobial Sepsis by Targeting TRAF6-Mediated Nuclear Factor κB Activation and p53-Mediated Apoptotic Signaling

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Structural basis of N6-adenosine methylation by the METTL3–METTL14 complex

(2016) Xiang Wang et al.   NATURE

MiRNA-Mediated Macrophage Polarization and its Potential Role in the Regulation of Inflammatory Response

(2016) Kobina Essandoh et al.   SHOCK

Oxidative Modification of miR-184 Enables It to Target Bcl-xL and Bcl-w

(2015) Jian-Xun Wang et al.   MOLECULAR CELL

N6-methyladenosine marks primary microRNAs for processing

(2015) Claudio R. Alarcón et al.   NATURE

Potentiality of a triple microRNA classifier: miR-193a-3p, miR-23a and miR-338-5p for early detection of colorectal cancer

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A METTL3–METTL14 complex mediates mammalian nuclear RNA N6-adenosine methylation

(2013) Jianzhao Liu et al.   Nature Chemical Biology

Epigenetic silencing of microRNA-193a contributes to leukemogenesis in t(8;21) acute myeloid leukemia by activating the PTEN/PI3K signal pathway

(2012) Y. Li et al.   BLOOD

Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq

(2012) Dan Dominissini et al.   NATURE

MicroRNA-193a represses c-kit expression and functions as a methylation-silenced tumor suppressor in acute myeloid leukemia

(2011) X-N Gao et al.   ONCOGENE