Dual specificity phosphatase 1 attenuates inflammation-induced cardiomyopathy by improving mitophagy and mitochondrial metabolism

Ketone Body β-Hydroxybutyrate Prevents Myocardial Oxidative Stress in Septic Cardiomyopathy

(2022) Liwei Ji et al.   Oxidative Medicine and Cellular Longevity

Inhibition of miR‑101‑3p protects against sepsis‑induced myocardial injury by inhibiting MAPK and NF‑κB pathway activation via the upregulation of DUSP1

(2021) Ye Xin et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Mitochondrial DNA alterations underlie an irreversible shift to aerobic glycolysis in fumarate hydratase–deficient renal cancer

(2021) Daniel R. Crooks et al.   Science Signaling

PERK inhibition attenuates vascular remodeling in pulmonary arterial hypertension caused by BMPR2 mutation

(2021) Takashi Shimizu et al.   Science Signaling

Novel Insights into the Molecular Features and Regulatory Mechanisms of Mitochondrial Dynamic Disorder in the Pathogenesis of Cardiovascular Disease

(2021) Ying Tan et al.   Oxidative Medicine and Cellular Longevity

Inositol 1,4,5-trisphosphate 3-kinase B promotes Ca2+ mobilization and the inflammatory activity of dendritic cells

(2021) Laura Marongiu et al.   Science Signaling

Pathogenetic mechanisms of septic cardiomyopathy

(2021) Runze Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypaphorine exerts anti‐inflammatory effects in sepsis induced acute lung injury via modulating DUSP1 /p38/ JNK pathway

(2021) Yu‐Hua Ding et al.   KAOHSIUNG JOURNAL OF MEDICAL SCIENCES

Irisin Attenuates Oxidative Stress, Mitochondrial Dysfunction, and Apoptosis in the H9C2 Cellular Model of Septic Cardiomyopathy through Augmenting Fundc1-Dependent Mitophagy

(2021) Xiaoqing Jiang et al.   Oxidative Medicine and Cellular Longevity

A genome-wide screen uncovers multiple roles for mitochondrial nucleoside diphosphate kinase D in inflammasome activation

(2021) Orna Ernst et al.   Science Signaling

Heat shock protein 27 activity is linked to endothelial barrier recovery after proinflammatory GPCR-induced disruption

(2021) Cara C. Rada et al.   Science Signaling

Neferine Ameliorates Sepsis-Induced Myocardial Dysfunction Through Anti-Apoptotic and Antioxidative Effects by Regulating the PI3K/AKT/mTOR Signaling Pathway

(2021) Zhen Qi et al.   Frontiers in Pharmacology

Mitophagy coordinates the mitochondrial unfolded protein response to attenuate inflammation-mediated myocardial injury

(2021) Yue Wang et al.   Redox Biology

The cGAS–STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy

(2021) Patrick Kwabena Oduro et al.   Acta Pharmaceutica Sinica B

Clostridium difficile toxin B induces colonic inflammation through the TRIM46/DUSP1/MAPKs and NF-κB signalling pathway

(2020) Ying Li et al.   Artificial Cells Nanomedicine and Biotechnology

SirT3 activates AMPK-related mitochondrial biogenesis and ameliorates sepsis-induced myocardial injury

(2020) Ting Xin et al.   Aging-US

Overexpression of Peroxisome Proliferator-Activated Receptor γ Coactivator 1-α Protects Cardiomyocytes from Lipopolysaccharide-Induced Mitochondrial Damage and Apoptosis

(2020) Tao Zhang et al.   INFLAMMATION

FUNDC1 interacts with FBXL2 to govern mitochondrial integrity and cardiac function through an IP3R3-dependent manner in obesity

(2020) Jun Ren et al.   Science Advances

Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control

(2020) Hang Zhu et al.   Redox Biology

Hyperglycemia-Driven Inhibition of AMP-Activated Protein Kinase α2 Induces Diabetic Cardiomyopathy by Promoting Mitochondria-AssociatedEndoplasmic Reticulum Membranes in vivo

(2019) Shengnan Wu et al.   CIRCULATION

Mitochondrial Injury and Targeted Intervention in Septic Cardiomyopathy

(2019) Ying Tan et al.   CURRENT PHARMACEUTICAL DESIGN

Doxorubicin-induced cardiomyocyte death is mediated by unchecked mitochondrial fission and mitophagy

(2019) Michael P. Catanzaro et al.   FASEB JOURNAL

Therapeutic contribution of melatonin to the treatment of septic cardiomyopathy: A novel mechanism linking Ripk3-modified mitochondrial performance and endoplasmic reticulum function

(2019) Jiankai Zhong et al.   Redox Biology

Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission

(2019) Jin Wang et al.   Redox Biology

NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α

(2018) Hao Zhou et al.   BASIC RESEARCH IN CARDIOLOGY

Pathogenesis of cardiac ischemia reperfusion injury is associated with CK2α-disturbed mitochondrial homeostasis via suppression of FUNDC1-related mitophagy

(2018) Hao Zhou et al.   CELL DEATH AND DIFFERENTIATION

DUSP1 Is a Potential Marker of Chronic Inflammation in Arabs with Cardiovascular Diseases

(2018) Abdelkrim Khadir et al.   DISEASE MARKERS

Mff‐Dependent Mitochondrial Fission Contributes to the Pathogenesis of Cardiac Microvasculature Ischemia/Reperfusion Injury via Induction of mROS‐Mediated Cardiolipin Oxidation and HK2/VDAC1 Disassociation‐Involved mPTP Opening

(2017) Hao Zhou et al.   Journal of the American Heart Association

AMPKα2 Protects Against the Development of Heart Failure by Enhancing Mitophagy via PINK1 Phosphorylation

(2017) Bei Wang et al.   CIRCULATION RESEARCH

Mitophagy receptor FUNDC1 regulates mitochondrial dynamics and mitophagy

(2016) Ming Chen et al.   Autophagy

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

(2012) Lei Liu et al.   NATURE CELL BIOLOGY

MAPK Signaling Drives Inflammation in LPS-Stimulated Cardiomyocytes: The Route of Crosstalk to G-Protein-Coupled Receptors

(2012) W. Joshua Frazier et al.   PLoS One

Deficiency of mitogen-activated protein kinase phosphatase-1 results in iNOS-mediated hypotension in response to low-dose endotoxin

(2008) Thomas J. Calvert et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Increased Endothelial Mitogen-Activated Protein Kinase Phosphatase-1 Expression Suppresses Proinflammatory Activation at Sites That Are Resistant to Atherosclerosis

(2008) Mustafa Zakkar et al.   CIRCULATION RESEARCH