Synthesis of 1,3,5-triphenyl-1,2,4-triazole derivatives and their neuroprotection by anti-oxidative stress and anti-inflammation and protecting BBB

Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential Nrf2 activators for the treatment of cerebral ischemic injury

(2022) Yaoqiang Lao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

circDlgap4 Alleviates Cerebral Ischaemic Injury by Binding to AUF1 to Suppress Oxidative Stress and Neuroinflammation

(2022) Huan Liu et al.   MOLECULAR NEUROBIOLOGY

Discovery of 1,2,4-triazole derivatives as novel neuroprotectants against cerebral ischemic injury by activating antioxidant response element

(2022) Yaoqiang Lao et al.   BIOORGANIC CHEMISTRY

Synthesis and biological evaluation of 1,2,4-oxadiazole core derivatives as potential neuroprotectants against acute ischemic stroke

(2021) Jinguo Shi et al.   NEUROCHEMISTRY INTERNATIONAL

Nanoparticles-mediated emerging approaches for effective treatment of ischemic stroke

(2021) Wenxiu He et al.   BIOMATERIALS

GPA Peptide Attenuates Sepsis-Induced Acute Lung Injury in Mice via Inhibiting Oxidative Stress and Pyroptosis of Alveolar Macrophage

(2021) Yukun Liu et al.   Oxidative Medicine and Cellular Longevity

Activation and Role of Astrocytes in Ischemic Stroke

(2021) Xin-Ya Shen et al.   Frontiers in Cellular Neuroscience

The Role of Heparin and Glycocalyx in Blood–Brain Barrier Dysfunction

(2021) Rui Yang et al.   Frontiers in Immunology

Synthesis and biological evaluation of 1,2,4-triazole derivatives as potential neuroprotectant against ischemic brain injury

(2020) Liping Liao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Synthetic Ruthenium Complex TQ-6 Potently Recovers Cerebral Ischemic Stroke: Attenuation of Microglia and Platelet Activation

(2020) Chih-Hsuan Hsia et al.   Journal of Clinical Medicine

Decreased endothelial glycocalyx thickness is an early predictor of mortality in sepsis

(2020) Daniëlle MH Beurskens et al.   ANAESTHESIA AND INTENSIVE CARE

Preparation, Characterization and in vivo Study of Borneol-Baicalin-Liposomes for Treatment of Cerebral Ischemia-Reperfusion Injury

(2020) Yulu Zhang et al.   International Journal of Nanomedicine

Microvascular dysfunction in COVID-19: the MYSTIC study

(2020) Alexandros Rovas et al.   ANGIOGENESIS

A structure-based computational workflow to predict liability and binding modes of small molecules to hERG

(2020) Subha Kalyaanamoorthy et al.   Scientific Reports

Do Clinicians Overestimate the Severity of Intracerebral Hemorrhage?

(2019) Elliot J. Tilling et al.   STROKE

Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

(2019) Jialin Duan et al.   Journal of Neuroinflammation

Anthology of stroke epidemiology in the 20th and 21st centuries: Assessing the past, the present, and envisioning the future

(2019) Valery L Feigin   International Journal of Stroke

Can We Use 2,3,5-Triphenyltetrazolium Chloride-Stained Brain Slices for Other Purposes? The Application of Western Blotting

(2019) Sonia Sanchez-Bezanilla et al.   Frontiers in Molecular Neuroscience

Neuroprotective Action of Teriflunomide in a Mouse Model of Transient Middle Cerebral Artery Occlusion

(2019) Zhengfang Lu et al.   NEUROSCIENCE

ent-Kaurane Diterpenoids with Neuroprotective Properties from Corn Silk (Zea mays)

(2018) Xiao-Li Qi et al.   JOURNAL OF NATURAL PRODUCTS

Celecoxib Treatment Improves Neurologic Deficit and Reduces Selective Neuronal Loss and Glial Response in Rats after Transient Middle Cerebral Artery Occlusion

(2018) María Santos-Galdiano et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

MiR-34b Protects Against Focal Cerebral Ischemia-Reperfusion (I/R) Injury in Rat by Targeting Keap1

(2018) Rong Huang et al.   Journal of Stroke & Cerebrovascular Diseases

The solid-state fermentation of Artemisia capillaris leaves with Ganoderma lucidum enhances the anti-inflammatory effects in a model of atopic dermatitis

(2017) Hyeong-U Son et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Glycocalyx degradation leads to blood–brain barrier dysfunction and brain edema after asphyxia cardiac arrest in rats

(2017) Jiajia Zhu et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Artemisinin conferred ERK mediated neuroprotection to PC12 cells and cortical neurons exposed to sodium nitroprusside-induced oxidative insult

(2016) Wenhua Zheng et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute Ischemic Stroke with Very Early Clinical Improvement: A National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trials Exploratory Analysis

(2016) Clotilde Balucani et al.   Journal of Stroke & Cerebrovascular Diseases

Acute Ischemic Stroke with Very Early Clinical Improvement: A National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Trials Exploratory Analysis

(2016) Clotilde Balucani et al.   Journal of Stroke & Cerebrovascular Diseases

Diabetic Stroke Severity: Epigenetic Remodeling and Neuronal, Glial, and Vascular Dysfunction

(2015) Anuradha Kalani et al.   DIABETES

Endothelial glycocalyx shedding and vascular permeability in severely injured trauma patients

(2015) Elaheh Rahbar et al.   Journal of Translational Medicine

In silico screening of the impact of hERG channel kinetic abnormalities on channel block and susceptibility to acquired long QT syndrome

(2014) Lucia Romero et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Intravenous Administration of Human Umbilical Tissue-Derived Cells Improves Neurological Function in Aged Rats after Embolic Stroke

(2013) Li Zhang et al.   CELL TRANSPLANTATION

Nanomechanics of the Endothelial Glycocalyx in Experimental Sepsis

(2013) Anne Wiesinger et al.   PLoS One

Inhibition of hERG Potassium Channels by Celecoxib and Its Mechanism

(2011) Roman V. Frolov et al.   PLoS One

The COXIB Experience: A Look in the Rearview Mirror

(2008) Lawrence J. Marnett   Annual Review of Pharmacology and Toxicology