Neuroprotective effect of Apelin 13 on ischemic stroke by activating AMPK/GSK-3β/Nrf2 signaling

A Dual AMPK/Nrf2 Activator Reduces Brain Inflammation After Stroke by Enhancing Microglia M2 Polarization

(2018) Yunjie Wang et al.   ANTIOXIDANTS & REDOX SIGNALING

Nrf2—a Promising Therapeutic Target for Defensing Against Oxidative Stress in Stroke

(2016) Rongrong Zhang et al.   MOLECULAR NEUROBIOLOGY

Melatonin protects against oxygen and glucose deprivation by decreasing extracellular glutamate and Nox-derived ROS in rat hippocampal slices

(2016) Paloma Patiño et al.   NEUROTOXICOLOGY

Apelin-13 protects against apoptosis by activating AMP-activated protein kinase pathway in ischemia stroke

(2016) Yi Yang et al.   PEPTIDES

Effect of apelin hormone on renal ischemia/reperfusion induced oxidative damage in rats

(2016) Burak Bircan et al.   RENAL FAILURE

The apelin receptor: physiology, pathology, cell signalling, and ligand modulation of a peptide-activated class A GPCR

(2014) Nigel A. Chapman et al.   Biochemistry and Cell Biology

Neuroprotective effect of nobiletin on cerebral ischemia–reperfusion injury in transient middle cerebral artery-occluded rats

(2014) Nodoka Yasuda et al.   BRAIN RESEARCH

Activation of AMP-activated protein kinase by metformin protects against global cerebral ischemia in male rats: Interference of AMPK/PGC-1α pathway

(2014) Ghorbangol Ashabi et al.   METABOLIC BRAIN DISEASE

Cardiovascular Events Associated With Smoking Cessation Pharmacotherapies

(2013) Edward J. Mills et al.   CIRCULATION

Apelin-13 Inhibits Apoptosis of Cortical Neurons Following Brain Ischemic Reperfusion Injury in a Transient Model of Focal Cerebral Ischemia

(2013) Nahid Aboutaleb et al.   International Journal of Peptide Research and Therapeutics

Apelin Attenuates Oxidative Stress in Human Adipocytes

(2013) Aung Than et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 Activators as Attractive Therapeutics for Diabetic Nephropathy: FIG. 1.

(2011) Judy B. de Haan   DIABETES

Neuroprotective effect of the endogenous neural peptide apelin in cultured mouse cortical neurons

(2010) Xiang Jun Zeng et al.   EXPERIMENTAL CELL RESEARCH

Activation of catalase by apelin prevents oxidative stress-linked cardiac hypertrophy

(2010) Camille Foussal et al.   FEBS LETTERS

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

AMPK in the brain: its roles in energy balance and neuroprotection

(2009) Gabriele V. Ronnett et al.   JOURNAL OF NEUROCHEMISTRY

Inflammatory mechanisms in ischemic stroke: therapeutic approaches

(2009) Shaheen E Lakhan et al.   Journal of Translational Medicine

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Functional interference between glycogen synthase kinase-3 beta and the transcription factor Nrf2 in protection against kainate-induced hippocampal celldeath

(2008) Ana I. Rojo et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Diabetic neuropathy: Mechanisms to management

(2008) James L. Edwards et al.   PHARMACOLOGY & THERAPEUTICS