Carpesii fructus extract exhibits neuroprotective effects in cellular and Caenorhabditis elegans models of Parkinson's disease

Targeting autophagy to discover the Piper wallichii petroleum ether fraction exhibiting antiaging and anti-Alzheimer's disease effects in Caenorhabditis elegans

(2023) Feng-Dan Zhu et al.   PHYTOMEDICINE

Therapeutic targeting of Ras/Raf/MAPK pathway by natural products: A systematic and mechanistic approach for neurodegeneration

(2023) Mohammad Mehdi Gravandi et al.   PHYTOMEDICINE

Two 18‐norspirostane steroidal saponins as novel mitophagy enhancers improve Alzheimer's disease

(2023) Wen‐Qiao Qiu et al.   Clinical and Translational Medicine

Biomarker of Neuroinflammation in Parkinson’s Disease

(2022) Tsai-Wei Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Critical Review of Zebrafish Models of Parkinson’s Disease

(2022) Jillian M. Doyle et al.   Frontiers in Pharmacology

Influence of heavy metals in Parkinson’s disease: an overview

(2022) Balachandar Vellingiri et al.   JOURNAL OF NEUROLOGY

Citri Reticulatae Semen Extract Promotes Healthy Aging and Neuroprotection via Autophagy Induction in Caenorhabditis elegans

(2022) Tao Long et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Ethnobotanical Uses, Phytochemical Composition, Biosynthesis, and Pharmacological Activities of Carpesium abrotanoides L. (Asteraceae)

(2022) Sabrin R. M. Ibrahim et al.   Plants-Basel

Neuroprotective Capability of Narcissoside in 6-OHDA-Exposed Parkinson’s Disease Models through Enhancing the MiR200a/Nrf-2/GSH Axis and Mediating MAPK/Akt Associated Signaling Pathway

(2022) Ru-Huei Fu et al.   Antioxidants

Galangin Exhibits Neuroprotective Effects in 6-OHDA-Induced Models of Parkinson’s Disease via the Nrf2/Keap1 Pathway

(2022) Qiu-Xu Chen et al.   Pharmaceuticals

Xanthotoxin modulates oxidative stress, inflammation, and MAPK signaling in a rotenone-induced Parkinson's disease model

(2022) Aya S. Sayed et al.   LIFE SCIENCES

Folium Hibisci Mutabilis extract, a potent autophagy enhancer, exhibits neuroprotective properties in multiple models of neurodegenerative diseases

(2022) Chang-Long He et al.   PHYTOMEDICINE

Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo

(2022) Seok Joon Won et al.   Antioxidants

High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS

(2021) Minsong Guo et al.   Acta Pharmaceutica Sinica B

Antiparasitic potential of ethanolic extracts of Carpesii Fructus against Miamiensis avidus in hirame natural embryo cell line and their effects on immune response- and biotransformation-related genes

(2021) Soo Ji Woo et al.   COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY

Polygala saponins inhibit NLRP3 inflammasome-mediated neuroinflammation via SHP-2-Mediated mitophagy

(2021) Wen-Qiao Qiu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer

(2020) Jin-Feng Teng et al.   Cancers

Lychee seed polyphenol inhibits Aβ-induced activation of NLRP3 inflammasome via the LRP1/AMPK mediated autophagy induction

(2020) Wen-Qiao Qiu et al.   BIOMEDICINE & PHARMACOTHERAPY

Oxidative Stress in Parkinson’s Disease: Potential Benefits of Antioxidant Supplementation

(2020) Sandro Percário et al.   Oxidative Medicine and Cellular Longevity

Mitochondria and Parkinson’s Disease: Clinical, Molecular, and Translational Aspects

(2020) Max Borsche et al.   Journal of Parkinsons Disease

Dietary Restriction Extends Lifespan through Metabolic Regulation of Innate Immunity

(2019) Ziyun Wu et al.   Cell Metabolism

α-Synuclein misfolding and aggregation: Implications in Parkinson’s disease pathogenesis

(2019) Surabhi Mehra et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Polyphyllin VI, a saponin from Trillium tschonoskii Maxim. induces apoptotic and autophagic cell death via the ROS triggered mTOR signaling pathway in non-small cell lung cancer

(2019) Jin-Feng Teng et al.   PHARMACOLOGICAL RESEARCH

The active components derived from Penthorum chinense Pursh protect against oxidative-stress-induced vascular injury via autophagy induction

(2019) Xiaolei Sun et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modeling Parkinson’s Disease in C. elegans

(2018) Jason F. Cooper et al.   Journal of Parkinsons Disease

Gene Therapy for Parkinson’s Disease, An Update

(2018) Tobias M. Axelsen et al.   Journal of Parkinsons Disease

MPK-1/ERK is required for the full activity of resveratrol in extended lifespan and reproduction

(2018) Dong Suk Yoon et al.   AGING CELL

Cognitive decline in Parkinson disease

(2017) Dag Aarsland et al.   Nature Reviews Neurology

Motor Complications of Dopaminergic Medications in Parkinson's Disease

(2017) Maria Freitas et al.   SEMINARS IN NEUROLOGY

A developmental toxicity assay of Carpesii Fructus on zebrafish embryos/larvae

(2017) Qing Xia et al.   Toxicology Research

Cellular models for Parkinson's disease

(2016) Björn H. Falkenburger et al.   JOURNAL OF NEUROCHEMISTRY

The epidemiology of Parkinson's disease: risk factors and prevention

(2016) Alberto Ascherio et al.   LANCET NEUROLOGY

Motor symptoms in Parkinson’s disease: A unified framework

(2016) Ahmed A. Moustafa et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Ageing and Parkinson's disease: Why is advancing age the biggest risk factor?

(2014) Amy Reeve et al.   AGEING RESEARCH REVIEWS

Models of α-synuclein aggregation in Parkinson’s disease

(2014) Rosa María Giráldez-Pérez et al.   Acta Neuropathologica Communications

Glia activation and its role in oxidative stress

(2013) Olalekan Michael Ogundele et al.   METABOLIC BRAIN DISEASE

Mitochondrial dysfunction and oxidative stress in Parkinson's disease

(2013) Sudhakar Raja Subramaniam et al.   PROGRESS IN NEUROBIOLOGY

IN VITROEVALUATION OF ANTI-INFLAMMATORY ACTIVITY FOR SALAD-FOOD MATERIALCARPESIUM ABROTANOIDES

(2011) JE-HYUK LEE et al.   JOURNAL OF FOOD BIOCHEMISTRY

Activation and Function of the MAPKs and Their Substrates, the MAPK-Activated Protein Kinases

(2011) M. Cargnello et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Review: Deep brain stimulation in Parkinson’s disease

(2009) S.J. Groiss et al.   Therapeutic Advances in Neurological Disorders