Folium Hibisci Mutabilis extract, a potent autophagy enhancer, exhibits neuroprotective properties in multiple models of neurodegenerative diseases

Citri Reticulatae Semen Extract Promotes Healthy Aging and Neuroprotection via Autophagy Induction in Caenorhabditis elegans

(2022) Tao Long et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Holistic quality evaluation of Hibisci Mutabilis Folium by integrating UPLC–QTOF–MS/MS chemical profiling and UPLC–TQ–MS/MS quantification approaches

(2022) Cheng-Ying Wu et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Antioxidant product analysis of Folium Hibisci Mutabilis

(2021) Yujie Hua et al.   Journal of Saudi Chemical Society

High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS

(2021) Minsong Guo et al.   Acta Pharmaceutica Sinica B

Effects of FUdR on gene expression in the C. elegans bacterial diet OP50

(2021) Grace McIntyre et al.   BMC Research Notes

Gardenia jasminoides J.Ellis extract GJ-4 alleviated cognitive deficits of APP/PS1 transgenic mice

(2021) Caixia Zang et al.   PHYTOMEDICINE

Strawberry (Fragaria × ananassa cv. Romina) methanolic extract attenuates Alzheimer’s beta amyloid production and oxidative stress by SKN-1/NRF and DAF-16/FOXO mediated mechanisms in C. elegans

(2021) María D. Navarro-Hortal et al.   FOOD CHEMISTRY

Autophagy in neurodegeneration: New insights underpinning therapy for neurological diseases

(2020) Olga Corti et al.   JOURNAL OF NEUROCHEMISTRY

Lychee seed polyphenol protects the blood–brain barrier through inhibiting Aβ(25–35)‐induced NLRP3 inflammasome activation via the AMPK / mTOR / ULK1‐mediated autophagy in bEnd .3 cells and APP / PS1 mice

(2020) Rui Xiong et al.   PHYTOTHERAPY RESEARCH

N‐butanol extract of Hedyotis diffusa protects transgenic Caenorhabditis elegans from Aβ‐induced toxicity

(2020) Li DanQing et al.   PHYTOTHERAPY RESEARCH

Targeting microglial autophagic degradation in NLRP3 inflammasome-mediated neurodegenerative diseases

(2020) An-Guo Wu et al.   AGEING RESEARCH REVIEWS

Age-dependent effects of floxuridine (FUdR) on senescent pathology and mortality in the nematode Caenorhabditis elegans

(2019) Hongyuan Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Autophagy as a molecular target of quercetin underlying its protective effects in human diseases

(2019) Milad Ashrafizadeh et al.   ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY

Measuring biological aging in humans: A quest

(2019) Luigi Ferrucci et al.   AGING CELL

Neuroprotective effects of curcumin through autophagy modulation

(2019) Fatemeh Forouzanfar et al.   IUBMB LIFE

Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases

(2019) Alvin Djajadikerta et al.   JOURNAL OF MOLECULAR BIOLOGY

Intercellular Spread of Protein Aggregates in Neurodegenerative Disease

(2018) Albert A. Davis et al.   Annual Review of Cell and Developmental Biology

Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

(2018) Claudio Soto et al.   NATURE NEUROSCIENCE

Mitochondrial dynamics, a key executioner in neurodegenerative diseases

(2018) Komal Panchal et al.   MITOCHONDRION

Crosstalk between mitochondrial dysfunction, oxidative stress, and age related neurodegenerative disease: Etiologies and therapeutic strategies

(2018) Hasnaa A. Elfawy et al.   LIFE SCIENCES

Approaches for Studying Autophagy in Caenorhabditis elegans

(2017) Yanfang Chen et al.   Cells

Anti-ageing active ingredients from herbs and nutraceuticals used in traditional Chinese medicine: pharmacological mechanisms and implications for drug discovery

(2016) Chun-Yan Shen et al.   BRITISH JOURNAL OF PHARMACOLOGY

p62 links the autophagy pathway and the ubiqutin–proteasome system upon ubiquitinated protein degradation

(2016) Wei Jing Liu et al.   CELLULAR & MOLECULAR BIOLOGY LETTERS

Determination of Rutin and Isoquercetin Contents in Hibisci mutabilis Folium in Different Collection Periods by HPLC

(2015) Diangang Liu et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Cranberry Extract Standardized for Proanthocyanidins Alleviates β-Amyloid Peptide Toxicity by Improving Proteostasis Through HSF-1 inCaenorhabditis elegansModel of Alzheimer’s Disease

(2015) Hong Guo et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Autophagy in Neurodegenerative Diseases: From Mechanism to Therapeutic Approach

(2015) Jihoon Nah et al.   MOLECULES AND CELLS

C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation

(2015) Jeong-Hoon Hahm et al.   Nature Communications

Hexosamine Pathway Metabolites Enhance Protein Quality Control and Prolong Life

(2014) Martin S. Denzel et al.   CELL

Autophagy in the physiology and pathology of the central nervous system

(2014) V Nikoletopoulou et al.   CELL DEATH AND DIFFERENTIATION

Oligomeric Aβ-induced synaptic dysfunction in Alzheimer’s disease

(2014) Shichun Tu et al.   Molecular Neurodegeneration

4-Hydroxybenzoic acid-mediated lifespan extension in Caenorhabditis elegans

(2014) Dae Keun Kim et al.   Journal of Functional Foods

Application and interpretation of current autophagy inhibitors and activators

(2013) Ya-ping Yang et al.   ACTA PHARMACOLOGICA SINICA

C. elegans in high-throughput drug discovery

(2013) Linda P. O'Reilly et al.   ADVANCED DRUG DELIVERY REVIEWS

Misregulation of autophagy and protein degradation systems in myopathies and muscular dystrophies

(2013) M. Sandri et al.   JOURNAL OF CELL SCIENCE

Worms under stress: C. elegans stress response and its relevance to complex human disease and aging

(2013) Miriam Rodriguez et al.   TRENDS IN GENETICS

Clinical trials of disease-modifying therapies for neurodegenerative diseases: the challenges and the future

(2010) Anthony E Lang   NATURE MEDICINE

Can Animal Models of Disease Reliably Inform Human Studies?

(2010) H. Bart van der Worp et al.   PLOS MEDICINE

Beclin 1 Gene Transfer Activates Autophagy and Ameliorates the Neurodegenerative Pathology in  -Synuclein Models of Parkinson's and Lewy Body Diseases

(2009) B. Spencer et al.   JOURNAL OF NEUROSCIENCE

Aging: An important factor for the pathogenesis of neurodegenerative diseases

(2008) Tahira Farooqui et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL