Urinary Excretion of Mercapturic Acids of the Rodent Carcinogen Methyleugenol after a Single Meal of Basil Pesto: A Controlled Exposure Study in Humans

p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol

(2022) Max J. Carlsson et al.   Cell Death & Disease

Cold stress changes antioxidant defense system, phenylpropanoid contents and expression of genes involved in their biosynthesis in Ocimum basilicum L.

(2020) Ramin Rezaie et al.   Scientific Reports

Expression of cytochrome P450 isozyme transcripts and activities in human livers

(2020) Jie Liu et al.   XENOBIOTICA

Detection of N-acetyl-S-[3'-(4-methoxyphenyl)allyl]-L-Cys (AMPAC) in Human Urine Samples after Controlled Exposure to Fennel Tea: A New Metabolite of Estragole and trans-Anethole

(2019) Bernhard H. Monien et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Urinary Methyleugenol-deoxyadenosine Adduct as a Potential Biomarker of Methyleugenol Exposure in Rats

(2018) Yukun Feng et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Exome Sequencing of Fresh-frozen or Formalin-fixed Paraffin-embedded B6C3F1/N Mouse Hepatocellular Carcinomas Arising Either Spontaneously or due to Chronic Chemical Exposure

(2018) Scott S. Auerbach et al.   TOXICOLOGIC PATHOLOGY

The effect of drought stress on the expression of key genes involved in the biosynthesis of phenylpropanoids and essential oil components in basil ( Ocimum basilicum L.)

(2017) Babak Abdollahi Mandoulakani et al.   PHYTOCHEMISTRY

Mutational spectra of aflatoxin B1in vivo establish biomarkers of exposure for human hepatocellular carcinoma

(2017) Supawadee Chawanthayatham et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mercapturic acids: recent advances in their determination by liquid chromatography/mass spectrometry and their use in toxicant metabolism studies and in occupational and environmental exposure studies

(2016) Patricia I. Mathias et al.   BIOMARKERS

Identification of glutathione and related cysteine conjugates derived from reactive metabolites of methyleugenol in rats

(2016) Huina Yao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Simultaneous determination of eugenol, isoeugenol and methyleugenol in fish fillet using gas chromatography coupled to tandem mass spectrometry

(2016) Changliang Ke et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

The influence of the SULT1A status – wild-type, knockout or humanized – on the DNA adduct formation by methyleugenol in extrahepatic tissues of mice

(2016) K. Herrmann et al.   Toxicology Research

Methyleugenol and oxidative metabolites induce DNA damage and interact with human topoisomerases

(2015) Isabel Anna Maria Groh et al.   ARCHIVES OF TOXICOLOGY

Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations

(2015) Ala′ A.A. Al-Subeihi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Simultaneous Detection of Multiple DNA Adducts in Human Lung Samples by Isotope-Dilution UPLC-MS/MS

(2014) Bernhard H. Monien et al.   ANALYTICAL CHEMISTRY

Impact of Structural and Metabolic Variations on the Toxicity and Carcinogenicity of Hydroxy- and Alkoxy-Substituted Allyl- and Propenylbenzenes

(2014) I. M. C. M. Rietjens et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Characterization and functional analysis of eugenol O-methyltransferase gene reveal metabolite shifts, chemotype specific differential expression and developmental regulation in Ocimum tenuiflorum L.

(2014) Indu Kumari Renu et al.   MOLECULAR BIOLOGY REPORTS

Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples

(2013) Kristin Herrmann et al.   CARCINOGENESIS

Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2

(2013) Kristin Herrmann et al.   CARCINOGENESIS

Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling

(2013) Ala′ A.A. Al-Subeihi et al.   FOOD AND CHEMICAL TOXICOLOGY

Comparison of GC/MS and NMR for quantification of methyleugenol in food

(2012) Sophia Grosch et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Methyl Eugenol: Its Occurrence, Distribution, and Role in Nature, Especially in Relation to Insect Behavior and Pollination

(2012) Keng Hong Tan et al.   JOURNAL OF INSECT SCIENCE

Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods

(2012) K. Herrmann et al.   MUTAGENESIS

Metabolism of Methyleugenol in Liver Microsomes and Primary Hepatocytes: Pattern of Metabolites, Cytotoxicity, and DNA-Adduct Formation

(2012) Alexander T. Cartus et al.   TOXICOLOGICAL SCIENCES

In Vivo Genotoxicity of Methyleugenol in gpt Delta Transgenic Rats Following Medium-Term Exposure

(2012) Meilan Jin et al.   TOXICOLOGICAL SCIENCES

Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat

(2012) Ala' A.A. Al-Subeihi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Hydroxymethyl-substituted furans: mutagenicity in Salmonella typhimurium strains engineered for expression of various human and rodent sulphotransferases

(2011) H. Glatt et al.   MUTAGENESIS

Genomics of ADME gene expression: mapping expression quantitative trait loci relevant for absorption, distribution, metabolism and excretion of drugs in human liver

(2011) A Schröder et al.   PHARMACOGENOMICS JOURNAL

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat

(2010) Ala′ A.A. Al-Subeihi et al.   TOXICOLOGY IN VITRO

Determination of alkenylbenzenes and related flavour compounds in food samples by on-column preconcentration-capillary liquid chromatography

(2009) Mónica Ávila et al.   JOURNAL OF CHROMATOGRAPHY A

Biomonitoring for occupational health risk assessment (BOHRA)☆

(2009) Maurizio Manno et al.   TOXICOLOGY LETTERS