The influence of the SULT1A status – wild-type, knockout or humanized – on the DNA adduct formation by methyleugenol in extrahepatic tissues of mice

Evaluation of the interindividual human variation in bioactivation of methyleugenol using physiologically based kinetic modeling and Monte Carlo simulations

(2015) Ala′ A.A. Al-Subeihi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Simultaneous Detection of Multiple DNA Adducts in Human Lung Samples by Isotope-Dilution UPLC-MS/MS

(2014) Bernhard H. Monien et al.   ANALYTICAL CHEMISTRY

Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples

(2013) Kristin Herrmann et al.   CARCINOGENESIS

Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2

(2013) Kristin Herrmann et al.   CARCINOGENESIS

Optimized enzymatic hydrolysis of DNA for LC–MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol

(2012) Fabian Schumacher et al.   ANALYTICAL BIOCHEMISTRY

Methyl Eugenol: Its Occurrence, Distribution, and Role in Nature, Especially in Relation to Insect Behavior and Pollination

(2012) Keng Hong Tan et al.   JOURNAL OF INSECT SCIENCE

Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods

(2012) K. Herrmann et al.   MUTAGENESIS

Metabolism of Methyleugenol in Liver Microsomes and Primary Hepatocytes: Pattern of Metabolites, Cytotoxicity, and DNA-Adduct Formation

(2012) Alexander T. Cartus et al.   TOXICOLOGICAL SCIENCES

Altered tissue distribution of 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine-DNA adducts in mice transgenic for human sulfotransferases 1A1 and 1A2

(2011) Gisela Dobbernack et al.   CARCINOGENESIS

Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic

(2010) Benjamin Smith et al.   FOOD AND CHEMICAL TOXICOLOGY

Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie"

(2009) Z. Riches et al.   DRUG METABOLISM AND DISPOSITION

Probenecid, an inhibitor of transmembrane organic anion transporters, alters tissue distribution of DNA adducts in 1-hydroxymethylpyrene-treated rats

(2009) Bernhard H. Monien et al.   TOXICOLOGY