Formation of hepatic DNA adducts by methyleugenol in mouse models: drastic decrease by Sult1a1 knockout and strong increase by transgenic human SULT1A1/2

Abundance of DNA adducts of methyleugenol, a rodent hepatocarcinogen, in human liver samples

(2013) Kristin Herrmann et al.   CARCINOGENESIS

Inhibition of methyleugenol bioactivation by the herb-based constituent nevadensin and prediction of possible in vivo consequences using physiologically based kinetic modeling

(2013) Ala′ A.A. Al-Subeihi et al.   FOOD AND CHEMICAL TOXICOLOGY

Optimized enzymatic hydrolysis of DNA for LC–MS/MS analyses of adducts of 1-methoxy-3-indolylmethyl glucosinolate and methyleugenol

(2012) Fabian Schumacher et al.   ANALYTICAL BIOCHEMISTRY

Methyleugenol hepatocellular cancer initiating effects in rat liver

(2012) Gary M. Williams et al.   FOOD AND CHEMICAL TOXICOLOGY

Identification of human and murine sulfotransferases able to activate hydroxylated metabolites of methyleugenol to mutagens in Salmonella typhimurium and detection of associated DNA adducts using UPLC-MS/MS methods

(2012) K. Herrmann et al.   MUTAGENESIS

Metabolism of Methyleugenol in Liver Microsomes and Primary Hepatocytes: Pattern of Metabolites, Cytotoxicity, and DNA-Adduct Formation

(2012) Alexander T. Cartus et al.   TOXICOLOGICAL SCIENCES

Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat

(2012) Ala' A.A. Al-Subeihi et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Genotoxic potential of methyleugenol and selected methyleugenol metabolites in cultured Chinese hamster V79 cells

(2012) Isabel Anna Maria Groh et al.   Food & Function

Altered tissue distribution of 2-amino-1-methyl-6-phenylimidazo[4,5- b ]pyridine-DNA adducts in mice transgenic for human sulfotransferases 1A1 and 1A2

(2011) Gisela Dobbernack et al.   CARCINOGENESIS

Metabolism of Methylisoeugenol in Liver Microsomes of Human, Rat, and Bovine Origin

(2011) A. T. Cartus et al.   DRUG METABOLISM AND DISPOSITION

Application of the margin of exposure (MoE) approach to substances in food that are genotoxic and carcinogenic

(2010) Benjamin Smith et al.   FOOD AND CHEMICAL TOXICOLOGY

Physiologically based biokinetic model of bioactivation and detoxification of the alkenylbenzene methyleugenol in rat

(2010) Ala′ A.A. Al-Subeihi et al.   TOXICOLOGY IN VITRO

Quantitative Evaluation of the Expression and Activity of Five Major Sulfotransferases (SULTs) in Human Tissues: The SULT "Pie"

(2009) Z. Riches et al.   DRUG METABOLISM AND DISPOSITION

Molecular Cloning, Expression and Characterization of A Novel Mouse SULT6 Cytosolic Sulfotransferase

(2009) S. Takahashi et al.   JOURNAL OF BIOCHEMISTRY

Structure and characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes

(2008) Tatsuki Fukami et al.   Pharmacogenetics and Genomics