A gB nanoparticle vaccine elicits a protective neutralizing antibody response against EBV

Clonally Expanded B Cells in Multiple Sclerosis Bind EBV EBNA1 and GlialCAM

(2022) Tobias V. Lanz et al.   NATURE

Longitudinal analysis reveals high prevalence of Epstein-Barr virus associated with multiple sclerosis

(2022) Kjetil Bjornevik et al.   SCIENCE

A bivalent Epstein-Barr virus vaccine induces neutralizing antibodies that block infection and confer immunity in humanized mice

(2022) Chih-Jen Wei et al.   Science Translational Medicine

How EBV Infects: The Tropism and Underlying Molecular Mechanism for Viral Infection

(2022) Guo-Long Bu et al.   Viruses-Basel

Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection

(2021) Philip J.M. Brouwer et al.   CELL

Epstein-Barr Virus and Systemic Autoimmune Diseases

(2021) Gunnar Houen et al.   Frontiers in Immunology

Immunization with a Self-Assembled Nanoparticle Vaccine Elicits Potent Neutralizing Antibody Responses against EBV Infection

(2021) Yin-Feng Kang et al.   NANO LETTERS

Nanotechnology approaches for global infectious diseases

(2021) Ameya R. Kirtane et al.   Nature Nanotechnology

Protein-based antigen presentation platforms for nanoparticle vaccines

(2021) Brian Nguyen et al.   npj Vaccines

A potent and protective human neutralizing antibody targeting a novel vulnerable site of Epstein-Barr virus

(2021) Qian-Ying Zhu et al.   Nature Communications

The landscape of viral associations in human cancers

(2020) Marc Zapatka et al.   NATURE GENETICS

Next-generation influenza vaccines: opportunities and challenges

(2020) Chih-Jen Wei et al.   NATURE REVIEWS DRUG DISCOVERY

A novel Epstein‐Barr virus subtype associated with nasopharyngeal carcinoma found in South China

(2020) Lawrence S. Young   Cancer Communications

Engineering Strategies for Lymph Node Targeted Immune Activation

(2020) Yong Chen et al.   ACCOUNTS OF CHEMICAL RESEARCH

The structural basis of herpesvirus entry

(2020) Sarah A. Connolly et al.   NATURE REVIEWS MICROBIOLOGY

UCSF ChimeraX : Structure visualization for researchers, educators, and developers

(2020) Eric F. Pettersen et al.   PROTEIN SCIENCE

Structural analysis of full-length SARS-CoV-2 spike protein from an advanced vaccine candidate

(2020) Sandhya Bangaru et al.   SCIENCE

Structure of Epstein-Barr virus tegument protein complex BBRF2-BSRF1 reveals its potential role in viral envelopment

(2020) Hui-Ping He et al.   Nature Communications

Structural Characterization and Modeling of a Respiratory Syncytial Virus Fusion Glycoprotein Nanoparticle Vaccine in Solution

(2020) Susan Krueger et al.   MOLECULAR PHARMACEUTICS

Eliciting B cell immunity against infectious diseases using nanovaccines

(2020) Ankur Singh   Nature Nanotechnology

Self-Assembling Nanoparticles Usher in a New Era of Vaccine Design

(2019) Rino Rappuoli et al.   CELL

Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus

(2019) Jessica Marcandalli et al.   CELL

Immunization with Components of the Viral Fusion Apparatus Elicits Antibodies That Neutralize Epstein-Barr Virus in B Cells and Epithelial Cells

(2019) Wei Bu et al.   IMMUNITY

Nanoparticle Size Influences Antigen Retention and Presentation in Lymph Node Follicles for Humoral Immunity

(2019) Yi-Nan Zhang et al.   NANO LETTERS

Epithelial cell infection by Epstein-Barr virus

(2019) Jia Chen et al.   FEMS MICROBIOLOGY REVIEWS

Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle

(2019) Philip J. M. Brouwer et al.   Nature Communications

An Antibody Targeting the Fusion Machinery Neutralizes Dual-Tropic Infection and Defines a Site of Vulnerability on Epstein-Barr Virus

(2018) Joost Snijder et al.   IMMUNITY

Primary Epstein-Barr virus infection

(2018) Samantha K. Dunmire et al.   JOURNAL OF CLINICAL VIROLOGY

Ephrin receptor A2 is an epithelial cell receptor for Epstein–Barr virus entry

(2018) Hua Zhang et al.   Nature Microbiology

emClarity: software for high-resolution cryo-electron tomography and subtomogram averaging

(2018) Benjamin A. Himes et al.   NATURE METHODS

Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers

(2018) Talar Tokatlian et al.   SCIENCE

Different functional states of fusion protein gB revealed on human cytomegalovirus by cryo electron tomography with Volta phase plate

(2018) Zhu Si et al.   PLoS Pathogens

MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

(2017) Shawn Q Zheng et al.   NATURE METHODS

cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination

(2017) Ali Punjani et al.   NATURE METHODS

Design of a hyperstable 60-subunit protein icosahedron

(2016) Yang Hsia et al.   NATURE

Accurate design of megadalton-scale two-component icosahedral protein complexes

(2016) J. B. Bale et al.   SCIENCE

Rabbits immunized with Epstein-Barr virus gH/gL or gB recombinant proteins elicit higher serum virus neutralizing activity than gp350

(2016) Xinle Cui et al.   VACCINE

Global burden of cancers attributable to infections in 2012: a synthetic analysis

(2016) Martyn Plummer et al.   Lancet Global Health

The Immunology of Epstein-Barr Virus–Induced Disease

(2015) Graham S. Taylor et al.   Annual Review of Immunology

Rational Design of an Epstein-Barr Virus Vaccine Targeting the Receptor-Binding Site

(2015) Masaru Kanekiyo et al.   CELL

Structure of a designed tetrahedral protein assembly variant engineered to have improved soluble expression

(2015) Jacob B. Bale et al.   PROTEIN SCIENCE

Structure of HCMV glycoprotein B in the postfusion conformation bound to a neutralizing human antibody

(2015) Sumana Chandramouli et al.   Nature Communications

Epstein-Barr Virus Glycoprotein gB and gHgL Can Mediate Fusion and Entry in trans, and Heat Can Act as a Partial Surrogate for gHgL and Trigger a Conformational Change in gB

(2014) L. S. Chesnokova et al.   JOURNAL OF VIROLOGY

Structure and immune recognition of trimeric pre-fusion HIV-1 Env

(2014) Marie Pancera et al.   NATURE

Accurate design of co-assembling multi-component protein nanomaterials

(2014) Neil P. King et al.   NATURE

Assembly and Architecture of the EBV B Cell Entry Triggering Complex

(2014) Karthik Sathiyamoorthy et al.   PLoS Pathogens

Structure-Based Design of a Fusion Glycoprotein Vaccine for Respiratory Syncytial Virus

(2013) J. S. McLellan et al.   SCIENCE

Whole-Genome Sequencing of the Akata and Mutu Epstein-Barr Virus Strains

(2012) Z. Lin et al.   JOURNAL OF VIROLOGY

Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy

(2012) N. P. King et al.   SCIENCE

Herpes Virus Fusion and Entry: A Story with Many Characters

(2012) Roselyn J. Eisenberg et al.   Viruses-Basel

Oil-in-Water Emulsion Adjuvant with Influenza Vaccine in Young Children

(2011) Timo Vesikari et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nasopharyngeal carcinoma: Advances in genomics and molecular genetics

(2011) ZhaoYang Zeng et al.   Science China-Life Sciences

Mapping regions of Epstein–Barr virus (EBV) glycoprotein B (gB) important for fusion function with gH/gL

(2011) Aileen E. Plate et al.   VIROLOGY

Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells

(2010) A. Moosmann et al.   BLOOD

Structure of a trimeric variant of the Epstein–Barr virus glycoprotein B

(2009) Marija Backovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Phase I Trial of Epstein-Barr Virus Gp350 Vaccine for Children With Chronic Kidney Disease Awaiting Transplantation

(2009) Lesley Rees et al.   TRANSPLANTATION

Molecular Basis of the Interaction between Complement Receptor Type 2 (CR2/CD21) and Epstein-Barr Virus Glycoprotein gp350

(2008) K. A. Young et al.   JOURNAL OF VIROLOGY