Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
Published 2019 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Enhancing and shaping the immunogenicity of native-like HIV-1 envelope trimers with a two-component protein nanoparticle
Authors
Keywords
-
Journal
Nature Communications
Volume 10, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-19
DOI
10.1038/s41467-019-12080-1
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Induction of Potent Neutralizing Antibody Responses by a Designed Protein Nanoparticle Vaccine for Respiratory Syncytial Virus
- (2019) Jessica Marcandalli et al. CELL
- Slow Delivery Immunization Enhances HIV Neutralizing Antibody and Germinal Center Responses via Modulation of Immunodominance
- (2019) Kimberly M. Cirelli et al. CELL
- Immunization expands B cells specific to HIV-1 V3 glycan in mice and macaques
- (2019) Amelia Escolano et al. NATURE
- Structure and immunogenicity of a stabilized HIV-1 envelope trimer based on a group-M consensus sequence
- (2019) Kwinten Sliepen et al. Nature Communications
- Precursor Frequency and Affinity Determine B Cell Competitive Fitness in Germinal Centers, Tested with Germline-Targeting HIV Vaccine Immunogens
- (2018) Robert K. Abbott et al. IMMUNITY
- Effects of Adjuvants on HIV-1 Envelope Glycoprotein SOSIP Trimers In Vitro
- (2018) Gabriel Ozorowski et al. JOURNAL OF VIROLOGY
- Epitopes for neutralizing antibodies induced by HIV-1 envelope glycoprotein BG505 SOSIP trimers in rabbits and macaques
- (2018) P. J. Klasse et al. PLoS Pathogens
- Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens
- (2018) Ivelin S. Georgiev et al. ACS Infectious Diseases
- Electron-Microscopy-Based Epitope Mapping Defines Specificities of Polyclonal Antibodies Elicited during HIV-1 BG505 Envelope Trimer Immunization
- (2018) Matteo Bianchi et al. IMMUNITY
- Innate immune recognition of glycans targets HIV nanoparticle immunogens to germinal centers
- (2018) Talar Tokatlian et al. SCIENCE
- Enhancing Humoral Responses Against HIV Envelope Trimers via Nanoparticle Delivery with Stabilized Synthetic Liposomes
- (2018) Talar Tokatlian et al. Scientific Reports
- Particulate Array of Well-Ordered HIV Clade C Env Trimers Elicits Neutralizing Antibodies that Display a Unique V2 Cap Approach
- (2017) Paola Martinez-Murillo et al. IMMUNITY
- The HIV-1 envelope glycoprotein structure: nailing down a moving target
- (2017) Andrew B Ward et al. IMMUNOLOGICAL REVIEWS
- Tfh cells and HIV bnAbs, an immunodominance model of the HIV neutralizing antibody generation problem
- (2017) Colin Havenar-Daughton et al. IMMUNOLOGICAL REVIEWS
- Native-like Env trimers as a platform for HIV-1 vaccine design
- (2017) Rogier W. Sanders et al. IMMUNOLOGICAL REVIEWS
- Design and crystal structure of a native-like HIV-1 envelope trimer that engages multiple broadly neutralizing antibody precursors in vivo
- (2017) Max Medina-Ramírez et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Covalent Linkage of HIV-1 Trimers to Synthetic Liposomes Elicits Improved B Cell and Antibody Responses
- (2017) Shridhar Bale et al. JOURNAL OF VIROLOGY
- Evolution of a designed protein assembly encapsulating its own RNA genome
- (2017) Gabriel L. Butterfield et al. NATURE
- MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy
- (2017) Shawn Q Zheng et al. NATURE METHODS
- Developing an HIV vaccine
- (2017) Barton F. Haynes et al. SCIENCE
- Improving the Immunogenicity of Native-like HIV-1 Envelope Trimers by Hyperstabilization
- (2017) Alba Torrents de la Peña et al. Cell Reports
- Broadly Neutralizing Antibodies to HIV and Their Role in Vaccine Design
- (2016) Dennis R. Burton et al. Annual Review of Immunology
- HIV Vaccine Design to Target Germline Precursors of Glycan-Dependent Broadly Neutralizing Antibodies
- (2016) Jon M. Steichen et al. IMMUNITY
- Beyond antigens and adjuvants: formulating future vaccines
- (2016) Tyson J. Moyer et al. JOURNAL OF CLINICAL INVESTIGATION
- Gctf: Real-time CTF determination and correction
- (2016) Kai Zhang JOURNAL OF STRUCTURAL BIOLOGY
- Design of a hyperstable 60-subunit protein icosahedron
- (2016) Yang Hsia et al. NATURE
- Accurate design of megadalton-scale two-component icosahedral protein complexes
- (2016) J. B. Bale et al. SCIENCE
- Presenting native-like trimeric HIV-1 antigens with self-assembling nanoparticles
- (2016) Linling He et al. Nature Communications
- Specifically modified Env immunogens activate B-cell precursors of broadly neutralizing HIV-1 antibodies in transgenic mice
- (2016) Andrew T. McGuire et al. Nature Communications
- High-Density Array of Well-Ordered HIV-1 Spikes on Synthetic Liposomal Nanoparticles Efficiently Activate B Cells
- (2016) Jidnyasa Ingale et al. Cell Reports
- Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies
- (2016) Laura E. McCoy et al. Cell Reports
- Accelerated cryo-EM structure determination with parallelisation using GPUs in RELION-2
- (2016) Dari Kimanius et al. eLife
- An HIV-1 antibody from an elite neutralizer implicates the fusion peptide as a site of vulnerability
- (2016) Marit J. van Gils et al. Nature Microbiology
- Self-assembling protein nanoparticles in the design of vaccines
- (2016) Jacinto López-Sagaseta et al. Computational and Structural Biotechnology Journal
- Immunogenicity of Stabilized HIV-1 Envelope Trimers with Reduced Exposure of Non-neutralizing Epitopes
- (2015) Steven W. de Taeye et al. CELL
- Structure-Guided Redesign Increases the Propensity of HIV Env To Generate Highly Stable Soluble Trimers
- (2015) Javier Guenaga et al. JOURNAL OF VIROLOGY
- EMRinger: side chain–directed model and map validation for 3D cryo-electron microscopy
- (2015) Benjamin A Barad et al. NATURE METHODS
- Design and structure of two HIV-1 clade C SOSIP.664 trimers that increase the arsenal of native-like Env immunogens
- (2015) Jean-Philippe Julien et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Presenting native-like HIV-1 envelope trimers on ferritin nanoparticles improves their immunogenicity
- (2015) Kwinten Sliepen et al. Retrovirology
- HIV-1 neutralizing antibodies induced by native-like envelope trimers
- (2015) R. W. Sanders et al. SCIENCE
- Antibodies to a conformational epitope on gp41 neutralize HIV-1 by destabilizing the Env spike
- (2015) Jeong Hyun Lee et al. Nature Communications
- Vaccine-Elicited Tier 2 HIV-1 Neutralizing Antibodies Bind to Quaternary Epitopes Involving Glycan-Deficient Patches Proximal to the CD4 Binding Site
- (2015) Ema T. Crooks et al. PLoS Pathogens
- Structure and immune recognition of trimeric pre-fusion HIV-1 Env
- (2014) Marie Pancera et al. NATURE
- Accurate design of co-assembling multi-component protein nanomaterials
- (2014) Neil P. King et al. NATURE
- Differential binding of neutralizing and non-neutralizing antibodies to native-like soluble HIV-1 Env trimers, uncleaved Env proteins, and monomeric subunits
- (2014) Anila Yasmeen et al. Retrovirology
- Why HIV Virions Have Low Numbers of Envelope Spikes: Implications for Vaccine Development
- (2014) John Schiller et al. PLoS Pathogens
- Cleavage strongly influences whether soluble HIV-1 envelope glycoprotein trimers adopt a native-like conformation
- (2013) R. P. Ringe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Next-Generation Cleaved, Soluble HIV-1 Env Trimer, BG505 SOSIP.664 gp140, Expresses Multiple Epitopes for Broadly Neutralizing but Not Non-Neutralizing Antibodies
- (2013) Rogier W. Sanders et al. PLoS Pathogens
- Anti-HIV B Cell Lines as Candidate Vaccine Biosensors
- (2012) T. Ota et al. JOURNAL OF IMMUNOLOGY
- HIV-1 Virus-Like Particles Bearing Pure Env Trimers Expose Neutralizing Epitopes but Occlude Nonneutralizing Epitopes
- (2012) T. Tong et al. JOURNAL OF VIROLOGY
- Enhancing humoral responses to a malaria antigen with nanoparticle vaccines that expand Tfh cells and promote germinal center induction
- (2012) J. J. Moon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
- (2012) N. P. King et al. SCIENCE
- Enzyme Digests Eliminate Nonfunctional Env from HIV-1 Particle Surfaces, Leaving Native Env Trimers Intact and Viral Infectivity Unaffected
- (2011) E. T. Crooks et al. JOURNAL OF VIROLOGY
- Few and Far Between: How HIV May Be Evading Antibody Avidity
- (2010) Joshua S. Klein et al. PLoS Pathogens
- MolProbity: all-atom structure validation for macromolecular crystallography
- (2009) Vincent B. Chen et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
- Refinement of Protein Structures into Low-Resolution Density Maps Using Rosetta
- (2009) Frank DiMaio et al. JOURNAL OF MOLECULAR BIOLOGY
- Nanoparticles target distinct dendritic cell populations according to their size
- (2008) Vania Manolova et al. EUROPEAN JOURNAL OF IMMUNOLOGY
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search