CRISPR/Cas12-Based Electrochemical Biosensors for Clinical Diagnostic and Food Monitoring

Photocurrent-Polarity-Switching Photoelectrochemical Biosensor for Switching Spatial Distance Electroactive Tags

(2023) Ruijin Zeng et al.   ACS Sensors

PAM-free cascaded strand displacement coupled with CRISPR-Cas12a for amplified electrochemical detection of SARS-CoV-2 RNA

(2023) Kai Shi et al.   ANALYTICAL BIOCHEMISTRY

Microelectromechanical Microsystems-Supported Photothermal Immunoassay for Point-of-Care Testing of Aflatoxin B1 in Foodstuff

(2023) Zhichao Yu et al.   Analytical Chemistry

Sensitive and selective DNA detecting electrochemical sensor via double cleaving CRISPR Cas12a and dual polymerization on hyperbranched rolling circle amplification

(2023) Juneseok You et al.   BIOSENSORS & BIOELECTRONICS

Cascade amplification strategy based on ultra-thin graphdiyne and CRISPR/Cas for real-time detection of tumor biomarker

(2023) Jing Xu et al.   CHEMICAL ENGINEERING JOURNAL

An electrochemical aptasensor based on exonuclease III-assisted signal amplification coupled with CRISPR-Cas12a for ochratoxin A detection

(2023) Chengyuan Wu et al.   FOOD CONTROL

Smart Graphene-Based Electrochemical Nanobiosensor for Clinical Diagnosis: Review

(2023) Irkham Irkham et al.   SENSORS

A CRISPR-Cas12a powered electrochemical sensor based on gold nanoparticles and MXene composite for enhanced nucleic acid detection

(2023) Haowei Duan et al.   SENSORS AND ACTUATORS B-CHEMICAL

Customization of aptamer to develop CRISPR/Cas12a-derived ultrasensitive biosensor

(2023) Wenping Xing et al.   TALANTA

The Optimization of a Label-Free Electrochemical DNA Biosensor for Detection of Sus scrofa mtDNA as Food Adulterations

(2023) Yeni Wahyuni Hartati et al.   Biosensors-Basel

CRISPR/Cas12a and primer-assisted rolling circle amplification integrated ultra-sensitive dual-signal sensing platform for EGFR 19 detection

(2023) Liyuan Deng et al.   Analytica Chimica Acta

A triple amplification strategy using GR-5 DNAzyme as a signal medium for ultrasensitive detection of trace Pb2+ based on CRISPR/Cas12a empowered electrochemical biosensor

(2023) Yuanyuan Yue et al.   Analytica Chimica Acta

Classification of CRISPR/Cas system and its application in tomato breeding

(2022) Abira Chaudhuri et al.   THEORETICAL AND APPLIED GENETICS

Electrochemical biosensor for nucleic acid amplification-free and sensitive detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA via CRISPR/Cas13a trans-cleavage reaction

(2022) Woong Heo et al.   BIOSENSORS & BIOELECTRONICS

CRISPR‐based point‐of‐care diagnostics incorporating Cas9, Cas12, and Cas13 enzymes advanced for SARS‐CoV‐2 detection

(2022) Monika K. Verma et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

A highly sensitive electrochemical aptasensor for cocaine detection based on CRISPR-Cas12a and terminal deoxynucleotidyl transferase as signal amplifiers

(2022) Khalil Abnous et al.   TALANTA

Size-Controlled Engineering Photoelectrochemical Biosensor for Human Papillomavirus-16 Based on CRISPR-Cas12a-Induced Disassembly of Z-Scheme Heterojunctions

(2022) Yuxuan Li et al.   ACS Sensors

Electrochemical Evaluation of Tumor Development via Cellular Interface Supported CRISPR/Cas Trans-Cleavage

(2022) Liangfen Cheng et al.   Research

Ultrasensitive SARS-CoV-2 diagnosis by CRISPR-based screen-printed carbon electrode

(2022) Lina Wu et al.   ANALYTICA CHIMICA ACTA

CRISPR/Cas12a-based electrochemical biosensor for highly sensitive detection of cTnI

(2022) Hao Chen et al.   BIOELECTROCHEMISTRY

CRISPR-Cas12a-mediated label-free electrochemical aptamer-based sensor for SARS-CoV-2 antigen detection

(2022) Na Liu et al.   BIOELECTROCHEMISTRY

Electrochemical detection of ctDNA mutation in non-small cell lung cancer based on CRISPR/Cas12a system

(2022) Feng Liu et al.   SENSORS AND ACTUATORS B-CHEMICAL

An electrochemical biosensor for PD-L1 positive exosomes based on ultra-thin two-dimensional covalent organic framework nanosheets coupled with CRISPR-Cas12a mediated signal amplification

(2022) Minghui Wang et al.   SENSORS AND ACTUATORS B-CHEMICAL

A general RPA-CRISPR/Cas12a sensing platform for Brucella spp. detection in blood and milk samples

(2022) Jianhao Xu et al.   SENSORS AND ACTUATORS B-CHEMICAL

XNA probe and CRISPR/Cas12a-powered flexible fluorescent and electrochemical dual-mode biosensor for sensitive detection of m6A site-specific RNA modification

(2022) Qinli Pu et al.   TALANTA

CRISPR-Cas12a-Empowered Electrochemical Biosensor for Rapid and Ultrasensitive Detection of SARS-CoV-2 Delta Variant

(2022) Chenshuo Wu et al.   Nano-Micro Letters

A lab-on-a-chip for the concurrent electrochemical detection of SARS-CoV-2 RNA and anti-SARS-CoV-2 antibodies in saliva and plasma

(2022) Devora Najjar et al.   Nature Biomedical Engineering

Point-of-Care Immunoassay Based on a Multipixel Dual-Channel Pressure Sensor Array with Visual Sensing Capability of Full-Color Switching and Reliable Electrical Signals

(2022) Lingting Huang et al.   ANALYTICAL CHEMISTRY

CRISPR/Cas12a-derived sensitive electrochemical biosensing of NF-κB p50 based on hybridization chain reaction and DNA hydrogel

(2022) Feng Qiu et al.   BIOSENSORS & BIOELECTRONICS

Highly sensitive and rapid detection of SARS‐CoV‐2 via a portable CRISPR‐Cas13a‐based lateral flow assay

(2022) Hongbo Liu et al.   JOURNAL OF MEDICAL VIROLOGY

Efficient Au nanocluster@Ti3C2 heterostructure luminophore combined with Cas12a for electrochemiluminescence detection of miRNA

(2022) Huixin Zhang et al.   SENSORS AND ACTUATORS B-CHEMICAL

An electrochemical sensing method based on CRISPR/Cas12a system and hairpin DNA probe for rapid and sensitive detection of Salmonella Typhimurium

(2022) Yawen He et al.   SENSORS AND ACTUATORS B-CHEMICAL

CRISPR/Cas12a-based photoelectrochemical sensing of microRNA on reduced graphene oxide-anchored Bi2WO6 coupling with catalytic hairpin assembly

(2022) Hexiang Gong et al.   SENSORS AND ACTUATORS B-CHEMICAL

Development of CRISPR-Mediated Nucleic Acid Detection Technologies and Their Applications in the Livestock Industry

(2022) Xuying Zhang   Genes

Click Chemistry Actuated Exponential Amplification Reaction Assisted CRISPR–Cas12a for the Electrochemical Detection of MicroRNAs

(2022) Hongguo Wei et al.   ACS Omega

Electrochemiluminescence biosensor for DNA adenine methylation methyltransferase based on CRISPR/Cas12a trans-cleavage-induced dual signal enhancement

(2022) Cuiying Lin et al.   TALANTA

An Ultrasensitive PCR-Based CRISPR-Cas13a Method for the Detection of Helicobacter pylori

(2022) Yaxuan Wang et al.   Journal of Personalized Medicine

An ultrasensitive and specific ratiometric electrochemical biosensor based on SRCA-CRISPR/Cas12a system for detection of Salmonella in food

(2022) Simeng Zheng et al.   FOOD CONTROL

Exploring the Trans-Cleavage Activity of CRISPR-Cas12a for the Development of a Mxene Based Electrochemiluminescence Biosensor for the Detection of Siglec-5

(2021) Kai Zhang et al.   BIOSENSORS & BIOELECTRONICS

Biosensors Based on Isothermal DNA Amplification for Bacterial Detection in Food Safety and Environmental Monitoring

(2021) Sandra Leonardo et al.   SENSORS

Cas12a-based electrochemiluminescence biosensor for target amplification-free DNA detection

(2021) Peng-Fei Liu et al.   BIOSENSORS & BIOELECTRONICS

CRISPR‐Cas12a System for Biosensing and Gene Regulation

(2021) Yuyan Shi et al.   Chemistry-An Asian Journal

Universal and Programmable Rolling Circle Amplification-CRISPR/Cas12a-Mediated Immobilization-Free Electrochemical Biosensor

(2021) Min Qing et al.   ANALYTICAL CHEMISTRY

Development of an Advanced DNA Biosensor for Pathogenic Vibrio Cholerae Detection in Real Sample

(2021) M.R. Ali et al.   BIOSENSORS & BIOELECTRONICS

Peptide-based electrochemical biosensors utilized for protein detection

(2021) Veronika Vanova et al.   BIOSENSORS & BIOELECTRONICS

An ultrasensitive CRISPR/Cas12a based electrochemical biosensor for Listeria monocytogenes detection

(2021) Fan Li et al.   BIOSENSORS & BIOELECTRONICS

Electrochemical Strategy for Low-Cost Viral Detection

(2021) Marjon Zamani et al.   ACS Central Science

DNA electrochemical biosensor for detection of Alicyclobacillus acidoterrestris utilizing Hoechst 33258 as indicator

(2021) José M.R. Flauzino et al.   BIOELECTROCHEMISTRY

An electrochemical biosensor for sensitive analysis of the SARS-CoV-2 RNA

(2021) Ying Peng et al.   BIOSENSORS & BIOELECTRONICS

CRISPR-Cas12-Based Rapid Authentication of Halal Food

(2021) Yinhuan Wu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

A label-free impedance biosensing assay based on CRISPR/Cas12a collateral activity for bacterial DNA detection

(2021) Andrea Bonini et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

CRISPR-Cas12a-Powered Dual-Mode Biosensor for Ultrasensitive and Cross-validating Detection of Pathogenic Bacteria

(2021) Long Ma et al.   ACS Sensors

Recent Advances in Electrochemical Biosensors: Applications, Challenges, and Future Scope

(2021) Anoop Singh et al.   Biosensors-Basel

Electrochemical biosensor for detecting pathogenic bacteria based on a hybridization chain reaction and CRISPR-Cas12a

(2021) Xiu Liu et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Detection of rare variant alleles using the AsCas12a double-stranded DNA trans-cleavage activity

(2021) Henson Lee Yu et al.   BIOSENSORS & BIOELECTRONICS

DNAzyme based three-way junction assay for antibody-free detection of locus-specific N6-methyladenosine modifications

(2021) Hongyan Yu et al.   BIOSENSORS & BIOELECTRONICS

A pH-engineering regenerative DNA tetrahedron ECL biosensor for the assay of SARS-CoV-2 RdRp gene based on CRISPR/Cas12a trans-activity

(2021) Kai Zhang et al.   CHEMICAL ENGINEERING JOURNAL

A CRISPR‐based nucleic acid detection platform (CRISPR‐CPA): Application for detection of Nocardia farcinica

(2021) Xiaotong Qiu et al.   JOURNAL OF APPLIED MICROBIOLOGY

CRISPR/Cas12a and immuno-RCA based electrochemical biosensor for detecting pathogenic bacteria

(2021) Zhibao Chen et al.   JOURNAL OF ELECTROANALYTICAL CHEMISTRY

Electrochemical Impedance Spectroscopy (EIS): Principles, Construction, and Biosensing Applications

(2021) Hend S. Magar et al.   SENSORS

Ultrasensitive detection of pathogenic bacteria by CRISPR/Cas12a coupling with a primer exchange reaction

(2021) Shengjun Bu et al.   SENSORS AND ACTUATORS B-CHEMICAL

A signal-switchable electrochemiluminescence biosensor based on the integration of spherical nucleic acid and CRISPR/Cas12a for multiplex detection of HIV/HPV DNAs

(2021) Kai-Ren Zhao et al.   SENSORS AND ACTUATORS B-CHEMICAL

A strategy combining 3D-DNA Walker and CRISPR-Cas12a trans-cleavage activity applied to MXene based electrochemiluminescent sensor for SARS-CoV-2 RdRp gene detection

(2021) Kai Zhang et al.   TALANTA

CRISPR/Cas12a-Derived electrochemical aptasensor for ultrasensitive detection of COVID-19 nucleocapsid protein

(2021) Cong Han et al.   BIOSENSORS & BIOELECTRONICS

Increased Detection of Viruses in Children with Respiratory Tract Infection Using PCR

(2020) Chien-Yu Lin et al.   International Journal of Environmental Research and Public Health

CRISPR/Cas12a-Mediated Interfacial Cleaving of Hairpin DNA Reporter for Electrochemical Nucleic Acid Sensing

(2020) Decai Zhang et al.   ACS Sensors

Surpassing the detection limit and accuracy of the electrochemical DNA sensor through the application of CRISPR Cas systems

(2020) Wei Xu et al.   BIOSENSORS & BIOELECTRONICS

High-throughput and all-solution phase African Swine Fever Virus (ASFV) detection using CRISPR-Cas12a and fluorescence based point-of-care system

(2020) Qian He et al.   BIOSENSORS & BIOELECTRONICS

SPR Enhanced DNA Biosensor for Sensitive Detection of Donkey Meat Adulteration

(2020) Maryam Mansouri et al.   FOOD CHEMISTRY

Nucleic Acid Detection Using CRISPR/Cas Biosensing Technologies

(2020) Rashid Aman et al.   ACS Synthetic Biology

CRISPR-dCas9 powered impedimetric biosensor for label-free detection of circulating tumor DNAs

(2020) Zihni Onur Uygun et al.   ANALYTICA CHIMICA ACTA

Electrochemical biosensors for pathogen detection

(2020) Ellen Cesewski et al.   BIOSENSORS & BIOELECTRONICS

Futuristic CRISPR-based biosensing in the cloud and internet of things era: an overview

(2020) Abdullahi Umar Ibrahim et al.   MULTIMEDIA TOOLS AND APPLICATIONS

Label-free homogeneous electrochemical biosensor for HPV DNA based on entropy-driven target recycling and hyperbranched rolling circle amplification

(2020) Yinghao He et al.   SENSORS AND ACTUATORS B-CHEMICAL

Superwettable electrochemical biosensor based on a dual-DNA walker strategy for sensitive E. coli O157: H7 DNA detection

(2020) Xiaoyan Zhang et al.   SENSORS AND ACTUATORS B-CHEMICAL

Trends and perspectives in DNA biosensors as diagnostic devices

(2020) Agata Kowalczyk   Current Opinion in Electrochemistry

Amplification-free DNA Sensor for the One-Step Detection of the Hepatitis B Virus Using an Automated Paper-Based Lateral Flow Electrochemical Device

(2020) Chawin Srisomwat et al.   ANALYTICAL CHEMISTRY

Advances in biosensing: The CRISPR/Cas system as a new powerful tool for the detection of nucleic acids

(2020) Andrea Bonini et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Efficient Gene Suppression by DNA/DNA Double-Stranded Oligonucleotide In Vivo

(2020) Yutaro Asami et al.   MOLECULAR THERAPY

Fabrication of ultrasensitive electrochemical biosensor for dengue fever viral RNA Based on CRISPR/Cpf1 reaction

(2020) Yeonju Lee et al.   SENSORS AND ACTUATORS B-CHEMICAL

Next-Generation Molecular Diagnostics Development by CRISPR/Cas Tool: Rapid Detection and Surveillance of Viral Disease Outbreaks

(2020) Sonal Srivastava et al.   Frontiers in Molecular Biosciences

Mechanistic Insights into the cis- and trans-Acting DNase Activities of Cas12a

(2019) Daan C. Swarts et al.   MOLECULAR CELL

Rapid and Fully Microfluidic Ebola Virus Detection with CRISPR-Cas13a

(2019) Peiwu Qin et al.   ACS Sensors

Wearable biosensors for healthcare monitoring

(2019) Jayoung Kim et al.   NATURE BIOTECHNOLOGY

A sensitive multiplex PCR protocol for simultaneous detection of chicken, duck, and pork in beef samples

(2019) Panzhu Qin et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

High-Fidelity and Rapid Quantification of miRNA Combining crRNA Programmability and CRISPR/Cas13a trans-Cleavage Activity

(2019) Yuanyue Shan et al.   ANALYTICAL CHEMISTRY

Electrochemical DNA biosensors for label-free breast cancer gene marker detection

(2019) Mehmet Senel et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

An electrochemical biosensor based on Hairpin-DNA modified gold electrode for detection of DNA damage by a hybrid cancer drug intercalation

(2019) Katherine Lozano Untiveros et al.   BIOSENSORS & BIOELECTRONICS

Label-free electrochemical DNA biosensor for zika virus identification

(2019) Henrique Antonio Mendonça Faria et al.   BIOSENSORS & BIOELECTRONICS

Disruptive Technology: CRISPR/Cas-Based Tools and Approaches

(2019) Petros Patsali et al.   Molecular Diagnosis & Therapy

Exploring the Trans-Cleavage Activity of CRISPR-Cas12a (cpf1) for the Development of a Universal Electrochemical Biosensor

(2019) Yifan Dai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Liposomal delivery of CRISPR/Cas9

(2019) Shuai Zhen et al.   CANCER GENE THERAPY

Electrical pulse-induced electrochemical biosensor for hepatitis E virus detection

(2019) Ankan Dutta Chowdhury et al.   Nature Communications

Optimisation of robust singleplex and multiplex droplet digital PCR assays for high confidence mutation detection in circulating tumour DNA

(2019) Vicky Rowlands et al.   Scientific Reports

History of CRISPR-Cas from Encounter with a Mysterious Repeated Sequence to Genome Editing Technology

(2018) Yoshizumi Ishino et al.   JOURNAL OF BACTERIOLOGY

Parallel detection of lactobacillus and bacterial vaginosis-associated bacterial DNA in the chorioamnion and vagina of pregnant women at term

(2018) Sophia M. R. Lannon et al.   Journal of Maternal-Fetal & Neonatal Medicine

Electrochemical detection of plant virus using gold nanoparticle-modified electrodes

(2018) Mohga Khater et al.   ANALYTICA CHIMICA ACTA

Advanced Carbon for Flexible and Wearable Electronics

(2018) Chunya Wang et al.   ADVANCED MATERIALS

CRISPR/Cas9 searches for a protospacer adjacent motif by lateral diffusion

(2018) Viktorija Globyte et al.   EMBO JOURNAL

Fully integrated nucleic acid pretreatment, amplification, and detection on a paper chip for identifying EGFR mutations in lung cancer cells

(2018) Peng Chen et al.   SENSORS AND ACTUATORS B-CHEMICAL

Lateral flow test for meat authentication with visual detection

(2018) Maria Magiati et al.   FOOD CHEMISTRY

Electrochemical DNA sensors based on the use of gold nanoparticles: a review on recent developments

(2017) Pathath Abdul Rasheed et al.   MICROCHIMICA ACTA

CUT-PCR: CRISPR-mediated, ultrasensitive detection of target DNA using PCR

(2017) S H Lee et al.   ONCOGENE

Electrochemical DNA biosensor for the detection of pathogenic bacteria Aeromonas hydrophila

(2013) M. Ligaj et al.   ELECTROCHIMICA ACTA

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

(2012) G. Gasiunas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function and Regulation of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) / CRISPR Associated (Cas) Systems

(2012) Corinna Richter et al.   Viruses-Basel

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

(2011) Elitza Deltcheva et al.   NATURE

Protein chips and nanomaterials for application in tumor marker immunoassays

(2009) Hui Chen et al.   BIOSENSORS & BIOELECTRONICS

Identification of meat species by TaqMan-based real-time PCR assay

(2009) Z. Kesmen et al.   MEAT SCIENCE