Berberine ameliorates renal interstitial inflammation and fibrosis in mice with unilateral ureteral obstruction

BCPT 2023 policy for experimental and clinical studies

(2023) Pernille Tveden‐Nyborg et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Berberine Reduces Lipid Accumulation by Promoting Fatty Acid Oxidation in Renal Tubular Epithelial Cells of the Diabetic Kidney

(2022) Qingfeng Rong et al.   Frontiers in Pharmacology

Nuclear farnesoid X receptor attenuates acute kidney injury through fatty acid oxidation

(2022) Sujuan Xu et al.   KIDNEY INTERNATIONAL

Rhein Improves Renal Fibrosis by Restoring Cpt1a-Mediated Fatty Acid Oxidation through SirT1/STAT3/twist1 Pathway

(2022) Xianrui Song et al.   MOLECULES

Berberine protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition involving the inactivation of the NLRP3 inflammasome

(2022) Zejun Ma et al.   RENAL FAILURE

Protective effects of berberine on various kidney diseases: Emphasis on the promising effects and the underlined molecular mechanisms

(2022) Emad H.M. Hassanein et al.   LIFE SCIENCES

Fibrosis in Chronic Kidney Disease: Pathogenesis and Consequences

(2021) Sara Panizo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Renal tubule Cpt1a overexpression protects from kidney fibrosis by restoring mitochondrial homeostasis

(2021) Verónica Miguel et al.   JOURNAL OF CLINICAL INVESTIGATION

Immunophenotypical Characterization of M1/M2 Macrophages and Lymphocytes in Cisplatin-Induced Rat Progressive Renal Fibrosis

(2021) Minto Nakagawa et al.   Cells

AMPK, metabolism, and vascular function

(2021) Claudia Rodríguez et al.   FEBS Journal

Multi-Pharmacology of Berberine in Atherosclerosis and Metabolic Diseases: Potential Contribution of Gut Microbiota

(2021) Shengjie Yang et al.   Frontiers in Pharmacology

The protective impact of berberine against doxorubicin-induced nephrotoxicity in rats

(2021) Ghadha Ibrahim Fouad et al.   TISSUE & CELL

Pathogenic Pathways and Therapeutic Approaches Targeting Inflammation in Diabetic Nephropathy

(2020) Sandra Rayego-Mateos et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Berberine attenuates severity of chronic pancreatitis and fibrosis via AMPK-mediated inhibition of TGF-β1/Smad signaling and M2 polarization

(2020) Sapana Bansod et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Role of the CTRP6/AMPK pathway in kidney fibrosis through the promotion of fatty acid oxidation

(2020) Yu-hong Xie et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Berberine protects against diabetic kidney disease via promoting PGC‐1α‐regulated mitochondrial energy homeostasis

(2019) Xin Qin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Berberine alleviates adipose tissue fibrosis by inducing AMP-activated kinase signaling in high-fat diet-induced obese mice

(2018) Lijun Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Cellular and molecular mechanisms of kidney fibrosis

(2018) Sonja Djudjaj et al.   MOLECULAR ASPECTS OF MEDICINE

Analysis of the Global Burden of Disease study highlights the global, regional, and national trends of chronic kidney disease epidemiology from 1990 to 2016

(2018) Yan Xie et al.   KIDNEY INTERNATIONAL

NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice

(2018) Ming Wu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Renoprotective effect of a novel selective PPARα modulator K-877 in db/db mice: A role of diacylglycerol-protein kinase C-NAD(P)H oxidase pathway

(2017) Toshinobu Maki et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

AMPK: guardian of metabolism and mitochondrial homeostasis

(2017) Sébastien Herzig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Effect of berberine on the renal tubular epithelial-to-mesenchymal transition by inhibition of the Notch/snail pathway in diabetic nephropathy model KKAy mice

(2017) Guannan Yang et al.   Drug Design Development and Therapy

NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis

(2016) Jianxiao Shen et al.   Scientific Reports

Anthocyanin-rich Seoritae extract ameliorates renal lipotoxicity via activation of AMP-activated protein kinase in diabetic mice

(2015) Eun Sil Koh et al.   Journal of Translational Medicine

Antioxidant and Anti-Inflammatory Activities of Berberine in the Treatment of Diabetes Mellitus

(2014) Zheng Li et al.   Evidence-based Complementary and Alternative Medicine

Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development

(2014) Hyun Mi Kang et al.   NATURE MEDICINE

Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model

(2013) Yuanmeng Jin et al.   LABORATORY INVESTIGATION

Berberine ameliorates experimental diabetes-induced renal inflammation and fibronectin by inhibiting the activation of RhoA/ROCK signaling

(2013) Xi Xie et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

MicroRNAs as mediators and therapeutic targets in chronic kidney disease

(2011) Johan M. Lorenzen et al.   Nature Reviews Nephrology