Elucidating the toxicity mechanisms of organophosphate esters by adverse outcome pathway network

Global warming and glyphosate toxicity (I): Adult zebrafish modelling with behavioural, immunohistochemical and metabolomic approaches

(2022) Ekrem Sulukan et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Comprehensive evaluation of organophosphate ester contamination in surface water and sediment of the Bohai Sea, China

(2021) Yanjie Qi et al.   MARINE POLLUTION BULLETIN

Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers

(2021) Heather B. Patisaul et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Bioaccumulation and translocation of organophosphate esters in a Mangrove Nature Reserve from the Pearl River Estuary, South China

(2021) Jinli Xie et al.   JOURNAL OF HAZARDOUS MATERIALS

Comparing the use of silicone wristbands, hand wipes, and dust to evaluate children's exposure to flame retardants and plasticizers

(2020) Stephanie C Hammel et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Organizing mechanism-related information on chemical interactions using a framework based on the aggregate exposure and adverse outcome pathways

(2020) Paul S. Price et al.   ENVIRONMENT INTERNATIONAL

The global environmental hazard of glyphosate use

(2020) Federico Maggi et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Global responses to tris(1-chloro-2-propyl)phosphate (TCPP) in rockfish Sebastes schlegeli using integrated proteomic and metabolomic approach

(2020) Chenglong Ji et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Organophosphorus flame retardants are developmental neurotoxicants in a rat primary brainsphere in vitro model

(2020) Helena T. Hogberg et al.   ARCHIVES OF TOXICOLOGY

Bioaccumulation and trophic transfer of organophosphate esters in tropical marine food web, South China Sea

(2020) Yang Ding et al.   ENVIRONMENT INTERNATIONAL

Occurrence and Trophic Magnification of Organophosphate Esters in an Antarctic Ecosystem: Insights into the Shift from Legacy to Emerging Pollutants

(2020) Jie Fu et al.   JOURNAL OF HAZARDOUS MATERIALS

The potential connections of adverse outcome pathways with the hazard identifications of typical organophosphate esters based on toxicity mechanisms

(2020) Zhenfei Yan et al.   CHEMOSPHERE

Phthalates and organophosphate esters in surface water, sediments and zooplankton of the NW Mediterranean Sea: Exploring links with microplastic abundance and accumulation in the marine food web

(2020) Natascha Schmidt et al.   ENVIRONMENTAL POLLUTION

Prioritization of hazards of novel flame retardants using the mechanistic toxicology information from ToxCast and Adverse Outcome Pathways

(2019) Lola Bajard et al.   Environmental Sciences Europe

The adverse effect of TCIPP and TCEP on neurodevelopment of zebrafish embryos/larvae

(2019) Ruiwen Li et al.   CHEMOSPHERE

Bioavailability and biomagnification of organophosphate esters in the food web of Taihu Lake, China: Impacts of chemical properties and metabolism

(2019) Xiaolei Wang et al.   ENVIRONMENT INTERNATIONAL

Assessing the threats of organophosphate esters (flame retardants and plasticizers) to drinking water safety based on USEPA oral reference dose (RfD) and oral cancer slope factor (SFO)

(2019) Jiafu Li et al.   WATER RESEARCH

Neurotoxicity of pesticides

(2019) Jason R. Richardson et al.   ACTA NEUROPATHOLOGICA

A nationwide survey of 19 organophosphate esters in soils from China: Spatial distribution and hazard assessment

(2019) Yu Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Organophosphate flame retardants (OPFRs) induce genotoxicity in vivo: A survey on apoptosis, DNA methylation, DNA oxidative damage, liver metabolites, and transcriptomics

(2019) Rui Chen et al.   ENVIRONMENT INTERNATIONAL

Temporal and seasonal variation and ecological risk evaluation of flame retardants in seawater and sediments from Bohai Bay near Tianjin, China during 2014 to 2017

(2019) Mengqin Chen et al.   MARINE POLLUTION BULLETIN

Occurrence, distribution and human exposure to 20 organophosphate esters in air, soil, pine needles, river water, and dust samples collected around an airport in New York state, United States

(2019) Wenhui Li et al.   ENVIRONMENT INTERNATIONAL

Deciphering Adverse Outcome Pathway Network Linked to Bisphenol F Using Text Mining and Systems Toxicology Approaches

(2019) Marylène Rugard et al.   TOXICOLOGICAL SCIENCES

Polybrominated diphenyl ethers and organophosphate esters flame retardants in play mats from China and the exposure risks for children

(2019) Bo Peng et al.   ENVIRONMENT INTERNATIONAL

Early-life exposure to the organophosphorus flame-retardant tris (1,3-dichloro-2-propyl) phosphate induces delayed neurotoxicity associated with DNA methylation in adult zebrafish

(2019) Ruiwen Li et al.   ENVIRONMENT INTERNATIONAL

A protective role of autophagy in TDCIPP-induced developmental neurotoxicity in zebrafish larvae

(2018) Ruiwen Li et al.   AQUATIC TOXICOLOGY

Oxidative stress, cell cycle arrest, DNA damage and apoptosis in adult zebrafish ( Danio rerio ) induced by tris(1,3-dichloro-2-propyl) phosphate

(2018) Hanyan Chen et al.   AQUATIC TOXICOLOGY

Occurrence and partitioning behavior of organophosphate esters in surface water and sediment of a shallow Chinese freshwater lake (Taihu Lake): Implication for eco-toxicity risk

(2018) Yanhua Liu et al.   CHEMOSPHERE

Risk ranking of environmental contaminants in Xiaoqing River, a heavily polluted river along urbanizing Bohai Rim

(2018) Qifeng Li et al.   CHEMOSPHERE

Accumulation of flame retardants in paired eggs and plasma of bald eagles

(2018) Jiehong Guo et al.   ENVIRONMENTAL POLLUTION

Organophosphate ester (OPEs) flame retardants and plasticizers in air and soil from a highly industrialized city in Turkey

(2018) Perihan Kurt-Karakus et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Developmental neurotoxicity of triphenyl phosphate in zebrafish larvae

(2018) Qipeng Shi et al.   AQUATIC TOXICOLOGY

Dopamine: Functions, Signaling, and Association with Neurological Diseases

(2018) Marianne O. Klein et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Parental transfer of tris(1,3-dichloro-2-propyl) phosphate and transgenerational inhibition of growth of zebrafish exposed to environmentally relevant concentrations

(2017) Liqin Yu et al.   ENVIRONMENTAL POLLUTION

Whole-Life-Stage Characterization in the Basic Biology of Daphnia magna and Effects of TDCIPP on Growth, Reproduction, Survival, and Transcription of Genes

(2017) Han Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Activation of Peroxisome Proliferator-Activated Receptor Gamma and Disruption of Progesterone Synthesis of 2-Ethylhexyl Diphenyl Phosphate in Human Placental Choriocarcinoma Cells: Comparison with Triphenyl Phosphate

(2017) Wenxin Hu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Organophosphate Ester Flame Retardants and Plasticizers in Ocean Sediments from the North Pacific to the Arctic Ocean

(2017) Yuxin Ma et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Organophosphate Esters in Sediment of the Great Lakes

(2017) Dandan Cao et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Review of OPFRs in animals and humans: Absorption, bioaccumulation, metabolism, and internal exposure research

(2016) Rui Hou et al.   CHEMOSPHERE

Multigenerational effects of tris(1,3-dichloro-2-propyl) phosphate on the free-living ciliate protozoa Tetrahymena thermophila exposed to environmentally relevant concentrations and after subsequent recovery

(2016) Jing Li et al.   ENVIRONMENTAL POLLUTION

Tris(1,3-dichloro-2-propyl)phosphate Induces Genome-Wide Hypomethylation within Early Zebrafish Embryos

(2016) David C. Volz et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Organophosphate Esters in Canadian Arctic Air: Occurrence, Levels and Trends

(2016) Roxana Sühring et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Developmental neurotoxicity of organophosphate flame retardants in early life stages of Japanese medaka (Oryzias latipes)

(2016) Liwei Sun et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity

(2016) Liwei Sun et al.   NEUROTOXICOLOGY AND TERATOLOGY

Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells

(2016) Gauthier Schang et al.   TOXICOLOGICAL SCIENCES

TPhP exposure disturbs carbohydrate metabolism, lipid metabolism, and the DNA damage repair system in zebrafish liver

(2016) Zhongkun Du et al.   Scientific Reports

Differential modulation of expression of nuclear receptor mediated genes by tris(2-butoxyethyl) phosphate (TBOEP) on early life stages of zebrafish (Danio rerio)

(2015) Zhiyuan Ma et al.   AQUATIC TOXICOLOGY

Aryl organophosphate flame retardants induced cardiotoxicity during zebrafish embryogenesis: By disturbing expression of the transcriptional regulators

(2015) Zhongkun Du et al.   AQUATIC TOXICOLOGY

Triphenyl phosphate-induced developmental toxicity in zebrafish: Potential role of the retinoic acid receptor

(2015) Gregory M. Isales et al.   AQUATIC TOXICOLOGY

Developmental exposure to the organophosphorus flame retardant tris(1,3-dichloro-2-propyl) phosphate: Estrogenic activity, endocrine disruption and reproductive effects on zebrafish

(2015) Qiangwei Wang et al.   AQUATIC TOXICOLOGY

Thyroid disruption by triphenyl phosphate, an organophosphate flame retardant, in zebrafish (Danio rerio) embryos/larvae, and in GH3 and FRTL-5 cell lines

(2015) Sujin Kim et al.   AQUATIC TOXICOLOGY

Effects of Tris(1,3-dichloro-2-propyl) Phosphate on Growth, Reproduction, and Gene Transcription of Daphnia magna at Environmentally Relevant Concentrations

(2015) Han Li et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Investigating Endocrine and Physiological Parameters of Captive American Kestrels Exposed by Diet to Selected Organophosphate Flame Retardants

(2015) Kimberly J. Fernie et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Bioconcentration and Transfer of the Organophorous Flame Retardant 1,3-Dichloro-2-propyl Phosphate Causes Thyroid Endocrine Disruption and Developmental Neurotoxicity in Zebrafish Larvae

(2015) Qiangwei Wang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Environmentally Relevant Concentrations of the Flame Retardant Tris(1,3-dichloro-2-propyl) Phosphate Inhibit Growth of Female Zebrafish and Decrease Fecundity

(2015) Ya Zhu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish

(2015) Kimberly A. Jarema et al.   NEUROTOXICOLOGY AND TERATOLOGY

Tracing organophosphorus and brominated flame retardants and plasticizers in an estuarine food web

(2015) Sicco H. Brandsma et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Multiple bio-analytical methods to reveal possible molecular mechanisms of developmental toxicity in zebrafish embryos/larvae exposed to tris(2-butoxyethyl) phosphate

(2014) Zhihua Han et al.   AQUATIC TOXICOLOGY

Ligand Binding and Activation of PPAR γ by Firemaster ® 550: Effects on Adipogenesis and Osteogenesis in Vitro

(2014) Hari K. Pillai et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Potential Estrogenic Effects of Phosphorus-Containing Flame Retardants

(2014) Quan Zhang et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Size-Dependent Toxicity of Silver Nanoparticles to Bacteria, Yeast, Algae, Crustaceans and Mammalian Cells In Vitro

(2014) Angela Ivask et al.   PLoS One

Developmental Exposure to Organophosphate Flame Retardants Elicits Overt Toxicity and Alters Behavior in Early Life Stage Zebrafish (Danio rerio)

(2014) Laura V. Dishaw et al.   TOXICOLOGICAL SCIENCES

In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components

(2014) Scott M. Belcher et al.   TOXICOLOGY LETTERS

Toxicity of TDCPP and TCEP on PC12 cell: Changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels

(2014) Na Ta et al.   TOXICOLOGY LETTERS

Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review

(2013) Olesja Bondarenko et al.   ARCHIVES OF TOXICOLOGY

Species- and tissue-specific mercury bioaccumulation in five fish species from Laizhou Bay in the Bohai Sea of China

(2013) Jinhu Liu et al.   CHINESE JOURNAL OF OCEANOLOGY AND LIMNOLOGY

Review of genotoxicity studies of glyphosate and glyphosate-based formulations

(2013) Larry D. Kier et al.   CRITICAL REVIEWS IN TOXICOLOGY

Toxicogenomic Responses of Zebrafish Embryos/Larvae to Tris(1,3-dichloro-2-propyl) Phosphate (TDCPP) Reveal Possible Molecular Mechanisms of Developmental Toxicity

(2013) Jie Fu et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

In vitro endocrine disruption potential of organophosphate flame retardants via human nuclear receptors

(2013) Hiroyuki Kojima et al.   TOXICOLOGY

Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish

(2012) Xiaoshan Liu et al.   AQUATIC TOXICOLOGY

Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic–pituitary–thyroid axis

(2012) Qiangwei Wang et al.   AQUATIC TOXICOLOGY

Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae

(2012) Chunsheng Liu et al.   AQUATIC TOXICOLOGY

Phosphorus flame retardants: Properties, production, environmental occurrence, toxicity and analysis

(2012) Ike van der Veen et al.   CHEMOSPHERE

Early Zebrafish Embryogenesis Is Susceptible to Developmental TDCPP Exposure

(2012) Sean P. McGee et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Toxicity of two types of silver nanoparticles to aquatic crustaceans Daphnia magna and Thamnocephalus platyurus

(2012) Irina Blinova et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Effects of Tris(1,3-dichloro-2-propyl) phosphate and Tris(1-chloropropyl) phosphate on Cytotoxicity and mRNA Expression in Primary Cultures of Avian Hepatocytes and Neuronal Cells

(2012) Doug Crump et al.   TOXICOLOGICAL SCIENCES

Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol

(2011) Yanbo Ma et al.   AQUATIC TOXICOLOGY

Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells

(2011) Laura V. Dishaw et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Occurrence and fate of organophosphorus flame retardants and plasticizers in coastal and marine surface waters

(2011) Ulla E. Bollmann et al.   WATER RESEARCH

Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment

(2010) Gerald T. Ankley et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

House Dust Concentrations of Organophosphate Flame Retardants in Relation to Hormone Levels and Semen Quality Parameters

(2009) John D. Meeker et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Evolution of developmental regulation in the vertebrate FgfD subfamily

(2009) Richard Jovelin et al.   JOURNAL OF EXPERIMENTAL ZOOLOGY PART B-MOLECULAR AND DEVELOPMENTAL EVOLUTION

Gene expression changes in developing zebrafish as potential markers for rapid developmental neurotoxicity screening

(2009) Chun-Yang Fan et al.   NEUROTOXICOLOGY AND TERATOLOGY

Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment

(2008) David L. Eaton et al.   CRITICAL REVIEWS IN TOXICOLOGY