Organophosphorus flame retardants are developmental neurotoxicants in a rat primary brainsphere in vitro model

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(2020) Feng Yi et al.   NEUROPHARMACOLOGY

Antidepressant Paroxetine Exerts Developmental Neurotoxicity in an iPSC-Derived 3D Human Brain Model

(2020) Xiali Zhong et al.   Frontiers in Cellular Neuroscience

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(2019) Timothy J Shafer et al.   TOXICOLOGICAL SCIENCES

Screening for neurotoxic potential of 15 flame retardants using freshwater planarians

(2019) Siqi Zhang et al.   NEUROTOXICOLOGY AND TERATOLOGY

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(2019) Nicoleta Spinu et al.   ARCHIVES OF TOXICOLOGY

Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?

(2019) Arlene Blum et al.   Environmental Science & Technology Letters

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(2018) Daniel L Villeneuve et al.   TOXICOLOGICAL SCIENCES

Developmental exposure to low concentrations of organophosphate flame retardants causes life-long behavioral alterations in zebrafish

(2018) Lilah Glazer et al.   TOXICOLOGICAL SCIENCES

Development of the Adverse Outcome Pathway (AOP): Chronic binding of antagonist to N -methyl- d -aspartate receptors (NMDARs) during brain development induces impairment of learning and memory abilities of children

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Rotenone exerts developmental neurotoxicity in a human brain spheroid model

(2018) David Pamies et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

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(2018) Anna Bal-Price   ALTEX-Alternatives to Animal Experimentation

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(2018) Gaëlle Diserens et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

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(2018) Ying Wang et al.   EXPERIMENTAL CELL RESEARCH

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(2018) Jyothsna Chitturi et al.   NEUROCHEMISTRY INTERNATIONAL

The link of organophosphorus pesticides with neurodegenerative and neurodevelopmental diseases based on evidence and mechanisms

(2018) Sara Mostafalou et al.   TOXICOLOGY

State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology

(2018) Natalie Alépée   ALTEX-Alternatives to Animal Experimentation

Safety of Safety Evaluation of Pesticides: developmental neurotoxicity of chlorpyrifos and chlorpyrifos-methyl

(2018) Axel Mie et al.   Environmental Health

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(2018) Aljoharah Alakkas et al.   JOURNAL OF NEUROVIROLOGY

Toxicity profiling of flame retardants in zebrafish embryos using a battery of assays for developmental toxicity, neurotoxicity, cardiotoxicity and hepatotoxicity toward human relevance

(2018) Ainhoa Alzualde et al.   NEUROTOXICOLOGY AND TERATOLOGY

Microglia Increase Inflammatory Responses in iPSC-Derived Human BrainSpheres

(2018) Celina Monteiro Abreu et al.   Frontiers in Microbiology

Halogen-free organophosphorus flame retardants caused oxidative stress and multixenobiotic resistance in Asian freshwater clams ( Corbicula fluminea )

(2017) Saihong Yan et al.   ENVIRONMENTAL POLLUTION

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(2017) Bi Su Ye et al.   ENVIRONMENTAL POLLUTION

Developmental neurotoxicity of the organophosphorus insecticide chlorpyrifos: from clinical findings to preclinical models and potential mechanisms

(2017) Richard D. Burke et al.   JOURNAL OF NEUROCHEMISTRY

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(2017) David S Wishart et al.   NUCLEIC ACIDS RESEARCH

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(2017) Ellen Fritsche   ALTEX-Alternatives to Animal Experimentation

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(2017) David Pamies   ALTEX-Alternatives to Animal Experimentation

Temporal Trends in Exposure to Organophosphate Flame Retardants in the United States

(2017) Kate Hoffman et al.   Environmental Science & Technology Letters

Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes

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Developmental exposure of zebrafish larvae to organophosphate flame retardants causes neurotoxicity

(2016) Liwei Sun et al.   NEUROTOXICOLOGY AND TERATOLOGY

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(2016) Michael Aschner   ALTEX-Alternatives to Animal Experimentation

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(2015) Anna Bal-Price et al.   CRITICAL REVIEWS IN TOXICOLOGY

TBBPA induces developmental toxicity, oxidative stress, and apoptosis in embryos and zebrafish larvae (Danio rerio)

(2015) Shengmin Wu et al.   ENVIRONMENTAL TOXICOLOGY

Developmental exposure to organophosphate flame retardants causes behavioral effects in larval and adult zebrafish

(2015) A.N. Oliveri et al.   NEUROTOXICOLOGY AND TERATOLOGY

Acute and developmental behavioral effects of flame retardants and related chemicals in zebrafish

(2015) Kimberly A. Jarema et al.   NEUROTOXICOLOGY AND TERATOLOGY

Use of alternative assays to identify and prioritize organophosphorus flame retardants for potential developmental and neurotoxicity

(2015) Mamta Behl et al.   NEUROTOXICOLOGY AND TERATOLOGY

Neurotoxicity of FireMaster 550® in zebrafish (Danio rerio): Chronic developmental and acute adolescent exposures

(2015) J.M. Bailey et al.   NEUROTOXICOLOGY AND TERATOLOGY

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(2015) J. B. Zimmerman et al.   SCIENCE

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(2015) Heiko J. Luhmann et al.   Frontiers in Cellular Neuroscience

A comparison of the in vitro cyto- and neurotoxicity of brominated and halogen-free flame retardants: prioritization in search for safe(r) alternatives

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Flame retardant associations between children’s handwipes and house dust

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N-methyl-d-aspartate glutamate receptor (NMDA-R) antibodies in mild cognitive impairment and dementias

(2014) Stefan Busse et al.   NEUROSCIENCE RESEARCH

Developmental Exposure to Organophosphate Flame Retardants Elicits Overt Toxicity and Alters Behavior in Early Life Stage Zebrafish (Danio rerio)

(2014) Laura V. Dishaw et al.   TOXICOLOGICAL SCIENCES

Impairment of Glutamate Signaling in Mouse Central Nervous System Neurons In Vitro by Tri-Ortho-Cresyl Phosphate at Noncytotoxic Concentrations

(2014) Vanessa Hausherr et al.   TOXICOLOGICAL SCIENCES

Developmental neurotoxicity – Challenges in the 21st Century and In Vitro Opportunities

(2014) Lena Smirnova   ALTEX-Alternatives to Animal Experimentation

Localisation of N-acetylaspartate in oligodendrocytes/myelin

(2013) Kaja Nordengen et al.   Brain Structure & Function

GABA estimation in the brains of children on the autism spectrum: Measurement precision and regional cortical variation

(2013) W. Gaetz et al.   NEUROIMAGE

Metabolomics Reveals Metabolic Alterations by Intrauterine Growth Restriction in the Fetal Rabbit Brain

(2013) Erwin van Vliet et al.   PLoS One

Efficient Generation of Astrocytes from Human Pluripotent Stem Cells in Defined Conditions

(2013) Atossa Shaltouki et al.   STEM CELLS

D-serine as a gliotransmitter and its roles in brain development and disease

(2013) Marion R. Van Horn et al.   Frontiers in Cellular Neuroscience

Brain IL-6 elevation causes neuronal circuitry imbalances and mediates autism-like behaviors

(2012) Hongen Wei et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Biotransformation of BDE-47 to Potentially Toxic Metabolites Is Predominantly Mediated by Human CYP2B6

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Synergistic interactions between PBDEs and PCBs in human neuroblastoma cells

(2012) C. Pellacani et al.   ENVIRONMENTAL TOXICOLOGY

Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy

(2012) Jeremy K Nicholson et al.   Expert Opinion on Drug Metabolism & Toxicology

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(2012) Erwin Sigel et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

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Halogenated Flame Retardants: Do the Fire Safety Benefits Justify the Risks?

(2011) Susan Shaw   REVIEWS ON ENVIRONMENTAL HEALTH

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(2010) Tomáš Pluskal et al.   BMC BIOINFORMATICS

Methamphetamine-induced neuronal protein NAT8L is the NAA biosynthetic enzyme: Implications for specialized acetyl coenzyme A metabolism in the CNS

(2010) Prasanth S. Ariyannur et al.   BRAIN RESEARCH

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(2010) Edith L.G.M. Tonnaer et al.   HEARING RESEARCH

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Regulation of early spontaneous network activity and GABAergic neurons development by thyroid hormone

(2010) S. Westerholz et al.   NEUROSCIENCE

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(2010) Joshua A. Harrill et al.   TOXICOLOGY IN VITRO

Prenatal Exposure to Organohalogens, Including Brominated Flame Retardants, Influences Motor, Cognitive, and Behavioral Performance at School Age

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Detection of Organophosphate Flame Retardants in Furniture Foam and U.S. House Dust

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(2009) Nadine Gogolla et al.   Journal of Neurodevelopmental Disorders

mRNA Expression is a Relevant Tool to Identify Developmental Neurotoxicants Using an In Vitro Approach

(2009) Helena T. Hogberg et al.   TOXICOLOGICAL SCIENCES

Neuronal in vitro models for the estimation of acute systemic toxicity

(2009) A. Forsby et al.   TOXICOLOGY IN VITRO

Low concentrations of the brominated flame retardants BDE-47 and BDE-99 induce synergistic oxidative stress-mediated neurotoxicity in human neuroblastoma cells

(2009) Sara Tagliaferri et al.   TOXICOLOGY IN VITRO

Significant features in the early prenatal development of the human brain

(2008) Ronan O’Rahilly et al.   ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER

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(2008) Darren Kessner et al.   BIOINFORMATICS

Potential developmental neurotoxicity of pesticides used in Europe

(2008) Marina Bjørling-Poulsen et al.   Environmental Health

Analyzing real-time PCR data by the comparative CT method

(2008) Thomas D Schmittgen et al.   Nature Protocols

Relevance of in vitro neurotoxicity testing for regulatory requirements: Challenges to be considered

(2008) Anna K. Bal-Price et al.   NEUROTOXICOLOGY AND TERATOLOGY

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(2008) D WANG et al.   PROGRESS IN NEUROBIOLOGY

Gene expression as a sensitive endpoint to evaluate cell differentiation and maturation of the developing central nervous system in primary cultures of rat cerebellar granule cells (CGCs) exposed to pesticides

(2008) Helena T. Hogberg et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

The role and the mechanism of γ-aminobutyric acid during central nervous system development

(2008) Ke Li et al.   Neuroscience Bulletin

A novel in vitro metabolomics approach for neurotoxicity testing, proof of principle for methyl mercury chloride and caffeine

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