Optimization of fluorescent substrates for ADAM17 and their utility in the detection of diabetes

Ultrasensitive Determination of Trypsin in Human Urine Based on Amplified Fluorescence Response

(2023) Taemin Park et al.   ACS Sensors

Matrix Metalloproteinases Repress Hypertrophic Growth in Cardiac Myocytes

(2021) Gerhild Euler et al.   CARDIOVASCULAR DRUGS AND THERAPY

Strategies to Target ADAM17 in Disease: From Its Discovery to the iRhom Revolution

(2021) Matteo Calligaris et al.   MOLECULES

Both Specific Endothelial and Proximal Tubular Adam17 Deletion Protect against Diabetic Nephropathy

(2021) Vanesa Palau et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Elastolytic activity is associated with inflammation in bladder cancer

(2021) Natalia Gruba et al.   JOURNAL OF BIOCHEMISTRY

ADAM 17 and Epithelial-to-Mesenchymal Transition: The Evolving Story and Its Link to Fibrosis and Cancer

(2021) Margherita Sisto et al.   Journal of Clinical Medicine

Urinary peptidomics reveals proteases involved in idiopathic membranous nephropathy

(2021) Baoxu Lin et al.   BMC GENOMICS

ADAM17, A Key Player of Cardiac Inflammation and Fibrosis in Heart Failure Development During Chronic Catecholamine Stress

(2021) Joseph Adu-Amankwaah et al.   Frontiers in Cell and Developmental Biology

Sarcoidosis as an Autoimmune Disease

(2020) Anna A. Starshinova et al.   Frontiers in Immunology

Development of Chemical Tools to Monitor Human Kallikrein 13 (KLK13) Activity

(2019) Natalia Gruba et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An Internally Quenched Fluorescent Peptide Substrate for Protealysin

(2019) Maria A. Karaseva et al.   Scientific Reports

Neutrophil and macrophage cell surface CSF-1 shed by ADAM17 drives mouse macrophage proliferation in acute and chronic inflammation

(2018) Jingjing Tang et al.   MOLECULAR AND CELLULAR BIOLOGY

Novel internally quenched substrate of the trypsin-like subunit of 20S eukaryotic proteasome

(2016) Natalia Gruba et al.   ANALYTICAL BIOCHEMISTRY

Adam17 Deficiency Promotes Atherosclerosis by Enhanced TNFR2 Signaling in MiceHighlights

(2016) Alexandros Nicolaou et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular Pathways: Receptor Ectodomain Shedding in Treatment, Resistance, and Monitoring of Cancer

(2016) Miles A. Miller et al.   CLINICAL CANCER RESEARCH

Renal endothelial protein C receptor expression and shedding during diabetic nephropathy

(2016) L. Lattenist et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

A Guide to Fluorescent Protein FRET Pairs

(2016) Bryce Bajar et al.   SENSORS

Interactions between kidney disease and diabetes: dangerous liaisons

(2016) Roberto Pecoits-Filho et al.   Diabetology & Metabolic Syndrome

ADAM-family metalloproteinases in lung inflammation: potential therapeutic targets

(2015) Daniela Dreymueller et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells

(2015) Renzhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diabetic nephropathy: landmark clinical trials and tribulations

(2015) Gary C.W. Chan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

ADAM17 at the interface between inflammation and autoimmunity

(2014) Sabrina Lisi et al.   IMMUNOLOGY LETTERS

Daily exercise training protects against albuminuria and angiotensin converting enzyme 2 shedding in db/db diabetic mice

(2014) Hari K Somineni et al.   JOURNAL OF ENDOCRINOLOGY

LC–MS Based Cleavage Site Profiling of the Proteases ADAM10 and ADAM17 Using Proteome-Derived Peptide Libraries

(2014) Joanna Tucher et al.   JOURNAL OF PROTEOME RESEARCH

Regulation of TIMP3 in diabetic nephropathy: a role for microRNAs

(2013) Loredana Fiorentino et al.   ACTA DIABETOLOGICA

The role of ADAM17 in metabolic inflammation

(2013) Rossella Menghini et al.   ATHEROSCLEROSIS

Substrate specificity of human matriptase-2

(2013) M. Wysocka et al.   BIOCHIMIE

Brain Angiotensin-Converting Enzyme Type 2 Shedding Contributes to the Development of Neurogenic Hypertension

(2013) Huijing Xia et al.   CIRCULATION RESEARCH

Role of epidermal growth factor receptor in acute and chronic kidney injury

(2013) Jinhua Tang et al.   KIDNEY INTERNATIONAL

Proteolytic Post-translational Modification of Proteins: Proteomic Tools and Methodology

(2013) Lindsay D. Rogers et al.   MOLECULAR & CELLULAR PROTEOMICS

ADAM17, shedding, TACE as therapeutic targets

(2013) Stefan Rose-John   PHARMACOLOGICAL RESEARCH

Three Wavelength Substrate System of Neutrophil Serine Proteinases

(2012) Magdalena Wysocka et al.   ANALYTICAL CHEMISTRY

MiR-222 modulates multidrug resistance in human colorectal carcinoma by down-regulating ADAM-17

(2012) Ke Xu et al.   EXPERIMENTAL CELL RESEARCH

Multimerisation of A disintegrin and metalloprotease protein-17 (ADAM17) is mediated by its EGF-like domain

(2011) Inken Lorenzen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sjögren's syndrome autoantibodies provoke changes in gene expression profiles of inflammatory cytokines triggering a pathway involving TACE/NF-κB

(2011) Sabrina Lisi et al.   LABORATORY INVESTIGATION

ADAM17: a molecular switch to control inflammation and tissue regeneration

(2011) Jürgen Scheller et al.   TRENDS IN IMMUNOLOGY

ADAM-17: A Target to Increase Chemotherapeutic Efficacy in Colorectal Cancer?

(2010) A. M. Lee et al.   CLINICAL CANCER RESEARCH

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

ADAM-17 over-expression in gallbladder carcinoma correlates with poor prognosis of patients

(2010) Kai Wu et al.   MEDICAL ONCOLOGY

Active-site determinants of substrate recognition by the metalloproteinases TACE and ADAM10

(2009) Cristina I. Caescu et al.   BIOCHEMICAL JOURNAL

The ADAM metalloproteinases

(2008) D EDWARDS et al.   MOLECULAR ASPECTS OF MEDICINE