Mitochondrial metabolism in alveolar macrophages of patients infected with HIV, tuberculosis (TB) and HIV/TB

Neutrophil extracellular traps in hepatocellular carcinoma are enriched in oxidized mitochondrial DNA which is highly pro-inflammatory and pro-metastatic

(2022) Lu-Yu Yang et al.   Journal of Cancer

Mitochondrial Functions Are Compromised in CD4 T Cells From ART-Controlled PLHIV

(2021) Juan Zhao et al.   Frontiers in Immunology

The interplay of DAMPs, TLR4, and proinflammatory cytokines in pulmonary fibrosis

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Immunometabolism during Mycobacterium tuberculosis Infection

(2020) Nicole C. Howard et al.   TRENDS IN MICROBIOLOGY

Chronic Immune Activation in TB/HIV Co-infection

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Mitochondria dysfunction and metabolic reprogramming as drivers of idiopathic pulmonary fibrosis

(2020) Marta Bueno et al.   Redox Biology

GM-CSF Reverses HIV Protein-Induced Mitochondrial Derangements in Alveolar Macrophages

(2020) Bashar Samih Staitieh et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

HIV and the tuberculosis “set point”: how HIV impairs alveolar macrophage responses to tuberculosis and sets the stage for progressive disease

(2020) Sara C. Auld et al.   Retrovirology

Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation

(2020) Melanie Genoula et al.   PLoS Pathogens

Host-Derived Lipids from Tuberculous Pleurisy Impair Macrophage Microbicidal-Associated Metabolic Activity

(2020) José Luis Marín Franco et al.   Cell Reports

Tricarboxylic acid cycle metabolites in the control of macrophage activation and effector phenotypes

(2019) Jordan T. Noe et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Macrophage heterogeneity and plasticity in tuberculosis

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YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial Homeostasis

(2019) Xin Zhou et al.   Cell Reports

CFTR-PTEN–dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection

(2019) Sebastián A. Riquelme et al.   Science Translational Medicine

The Metabolic Signature of Macrophage Responses

(2019) Antonella Viola et al.   Frontiers in Immunology

Diversity, Mechanisms, and Significance of Macrophage Plasticity

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Some Aspects of CD8+ T-Cell Exhaustion Are Associated With Altered T-Cell Mitochondrial Features and ROS Content in HIV Infection

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Cholesterol and fatty acids grease the wheels of Mycobacterium tuberculosis pathogenesis

(2018) Kaley M Wilburn et al.   Pathogens and Disease

Alcohol-induced mitochondrial DNA damage promotes injurious crosstalk between alveolar epithelial cells and alveolar macrophages

(2018) Ruxana T. Sadikot et al.   ALCOHOL

Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1

(2018) Evanna L. Mills et al.   NATURE

Mycobacterium tuberculosis carrying a rifampicin drug resistance mutation reprograms macrophage metabolism through cell wall lipid changes

(2018) Nicole C. Howard et al.   Nature Microbiology

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Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

HIV-infected macrophages and microglia that survive acute infection become viral reservoirs by a mechanism involving Bim

(2017) Paul Castellano et al.   Scientific Reports

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

(2016) Evanna L. Mills et al.   CELL

HIF-1α Is an Essential Mediator of IFN-γ–Dependent Immunity toMycobacterium tuberculosis

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HIV-1 and the Mycobacterium tuberculosis granuloma: A systematic review and meta-analysis

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Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages

(2016) Jan Van den Bossche et al.   Cell Reports

Healthy HIV-1-Infected Individuals on Highly Active Antiretroviral Therapy Harbor HIV-1 in Their Alveolar Macrophages

(2015) Sushma K. Cribbs et al.   AIDS RESEARCH AND HUMAN RETROVIRUSES

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

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Fatty Acid Trafficking in Starved Cells: Regulation by Lipid Droplet Lipolysis, Autophagy, and Mitochondrial Fusion Dynamics

(2015) Angelika S. Rambold et al.   DEVELOPMENTAL CELL

Intracellular expression of Tat alters mitochondrial functions in T cells: a potential mechanism to understand mitochondrial damage during HIV-1 replication

(2015) Sara Rodríguez-Mora et al.   Retrovirology

Asymptomatic HIV-infected Individuals on Antiretroviral Therapy Exhibit Impaired Lung CD4+T-Cell Responses to Mycobacteria

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The Role of Macrophage Polarization in Infectious and Inflammatory Diseases

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Roles Nrf2 Plays in Myeloid Cells and Related Disorders

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Hypoxia Triggers the Expression of Human   Defensin 2 and Antimicrobial Activity against Mycobacterium tuberculosis in Human Macrophages

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HIV-1/Mycobacterium tuberculosisCoinfection Immunology: How Does HIV-1 Exacerbate Tuberculosis?

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TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Targeting Nrf2 Signaling Improves Bacterial Clearance by Alveolar Macrophages in Patients with COPD and in a Mouse Model

(2011) C. J. Harvey et al.   Science Translational Medicine

Macrophage polarization: convergence point targeted by Mycobacterium tuberculosis and HIV

(2011) Geanncarlo Lugo-Villarino   Frontiers in Immunology

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Effects of In Vitro HIV-1 Infection on Mycobacterial Growth in Peripheral Blood Monocyte-Derived Macrophages

(2010) S. Pathak et al.   INFECTION AND IMMUNITY

The macrophage in HIV-1 infection: From activation to deactivation?

(2010) Georges Herbein et al.   Retrovirology

Foamy macrophages and the progression of the human tuberculosis granuloma

(2009) David G Russell et al.   NATURE IMMUNOLOGY