Large-scale Bioinformatic Study of Graspimiditides and Structural Characterization of Albusimiditide

Kinetics of Aspartimide Formation and Hydrolysis in Lasso Peptide Lihuanodin

(2023) Li Cao et al.   Biochemistry

Discovery, function, and engineering of graspetides

(2023) Brian Choi et al.   Trends in Chemistry

Protein Engineering in Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs)

(2022) Truc Do et al.   BIOCHEMISTRY

Phylogenomic analysis of the diversity of graspetides and proteins involved in their biosynthesis

(2022) Kira S. Makarova et al.   Biology Direct

A Silent Biosynthetic Gene Cluster from a Methanotrophic Bacterium Potentiates Discovery of a Substrate Promiscuous Proteusin Cyclodehydratase

(2022) Nguyet A. Nguyen et al.   ACS Chemical Biology

Applying Promiscuous RiPP Enzymes to Peptide Backbone N-Methylation Chemistry

(2022) Snigdha Sarkar et al.   ACS Chemical Biology

Leveraging Substrate Promiscuity of a Radical S-Adenosyl-L-methionine RiPP Maturase toward Intramolecular Peptide Cross-Linking Applications

(2022) Karsten A. S. Eastman et al.   ACS Central Science

Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide

(2022) Hader E. Elashal et al.   Nature Chemistry

A scalable platform to discover antimicrobials of ribosomal origin

(2022) Richard S. Ayikpoe et al.   Nature Communications

Mechanistic Analysis of the Biosynthesis of the Aspartimidylated Graspetide Amycolimiditide

(2022) Brian Choi et al.   Journal of the American Chemical Society

Mechanisms of Action of Ribosomally Synthesized and Posttranslationally Modified Peptides (RiPPs)

(2021) Li Cao et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Natural products in drug discovery: advances and opportunities

(2021) Atanas G. Atanasov et al.   NATURE REVIEWS DRUG DISCOVERY

Heterologous expression of a cryptic gene cluster from Marinomonas fungiae affords a novel tricyclic peptide marinomonasin

(2021) Issara Kaweewan et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Cellulonodin-2 and Lihuanodin: Lasso Peptides with an Aspartimide Post-Translational Modification

(2021) Li Cao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Bioinformatics-Guided Expansion and Discovery of Graspetides

(2021) Sangeetha Ramesh et al.   ACS Chemical Biology

Genome Mining Reveals High Topological Diversity of ω-Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases

(2020) Hyunbin Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterologous expression of cryptic biosynthetic gene cluster from Streptomyces prunicolor yields novel bicyclic peptide prunipeptin

(2020) Kohta Unno et al.   MICROBIOLOGICAL RESEARCH

Insights into AMS/PCAT transporters from biochemical and structural characterization of a double Glycine motif protease

(2019) Silvia C Bobeica et al.   eLife

O-Methyltransferase-mediated Incorporation of a β-Amino Acid in Lanthipeptides

(2019) Jeella Z. Acedo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A topologically distinct modified peptide with multiple bicyclic core motifs expands the diversity of microviridin-like peptides

(2018) Heejin Roh et al.   CHEMBIOCHEM

Expanded Natural Product Diversity Revealed by Analysis of Lanthipeptide-Like Gene Clusters in Actinobacteria

(2015) Qi Zhang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Taxonomy, Physiology, and Natural Products of Actinobacteria

(2015) Essaid Ait Barka et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Leading the way to RiPPs

(2015) A James Link   Nature Chemical Biology

Harnessing the Evolvability of Tricyclic Microviridins To Dissect Protease-Inhibitor Interactions

(2014) Annika R. Weiz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Investigations of the Mechanism of the “Proline Effect” in Tandem Mass Spectrometry Experiments: The “Pipecolic Acid Effect”

(2014) Mary Disa M. Raulfs et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

Towards Understanding the Tandem Mass Spectra of Protonated Oligopeptides. 2: The Proline Effect in Collision-Induced Dissociation of Protonated Ala-Ala-Xxx-Pro-Ala (Xxx = Ala, Ser, Leu, Val, Phe, and Trp)

(2011) Christian Bleiholder et al.   JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY

In silico analysis highlights the frequency and diversity of type 1 lantibiotic gene clusters in genome sequenced bacteria

(2010) Alan J Marsh et al.   BMC GENOMICS

Substrate Specificity and Scope of MvdD, a GRASP-like Ligase from the Microviridin Biosynthetic Gene Cluster

(2009) Benjamin Philmus et al.   ACS Chemical Biology