Heterologous expression of a cryptic gene cluster from Marinomonas fungiae affords a novel tricyclic peptide marinomonasin

Structural Basis for a Dual Function ATP Grasp Ligase That Installs Single and Bicyclic ω-Ester Macrocycles in a New Multicore RiPP Natural Product

(2021) Gengxiang Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Genome Mining Reveals High Topological Diversity of ω-Ester-Containing Peptides and Divergent Evolution of ATP-Grasp Macrocyclases

(2020) Hyunbin Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterologous expression of a cryptic gene cluster from Grimontia marina affords a novel tricyclic peptide grimoviridin

(2020) Kohta Unno et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Heterologous expression of cryptic biosynthetic gene cluster from Streptomyces prunicolor yields novel bicyclic peptide prunipeptin

(2020) Kohta Unno et al.   MICROBIOLOGICAL RESEARCH

Unlocking the Spatial Control of Secondary Metabolism Uncovers Hidden Natural Product Diversity in Nostoc punctiforme

(2019) Daniel Dehm et al.   ACS Chemical Biology

Introduction of Bifunctionality into the Multidomain Architecture of the ω-Ester-Containing Peptide Plesiocin

(2019) Chanwoo Lee et al.   BIOCHEMISTRY

A distributive peptide cyclase processes multiple microviridin core peptides within a single polypeptide substrate

(2018) Yi Zhang et al.   Nature Communications

Heterologous production of a new lasso peptide brevunsin in Sphingomonas subterranea

(2018) Shinya Kodani et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

A topologically distinct modified peptide with multiple bicyclic core motifs expands the diversity of microviridin-like peptides

(2018) Heejin Roh et al.   CHEMBIOCHEM

Leader Peptide-Free In Vitro Reconstitution of Microviridin Biosynthesis Enables Design of Synthetic Protease-Targeted Libraries

(2016) Emmanuel Reyna-González et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Structural basis for precursor protein–directed ribosomal peptide macrocyclization

(2016) Kunhua Li et al.   Nature Chemical Biology

Harnessing the Evolvability of Tricyclic Microviridins To Dissect Protease-Inhibitor Interactions

(2014) Annika R. Weiz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Functional Analysis of Environmental DNA-Derived Microviridins Provides New Insights into the Diversity of the Tricyclic Peptide Family

(2013) Douglas Gatte-Picchi et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Expanded genetic code for the engineering of ribosomally synthetized and post-translationally modified peptide natural products (RiPPs)

(2013) Nediljko Budisa   CURRENT OPINION IN BIOTECHNOLOGY

Leader Peptide and a Membrane Protein Scaffold Guide the Biosynthesis of the Tricyclic Peptide Microviridin

(2011) Annika R. Weiz et al.   CHEMISTRY & BIOLOGY

Exploiting the Natural Diversity of Microviridin Gene Clusters for Discovery of Novel Tricyclic Depsipeptides

(2010) N. Ziemert et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Ribosomal Synthesis of Tricyclic Depsipeptides in Bloom-Forming Cyanobacteria

(2008) Nadine Ziemert et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Post-translational Modification in Microviridin Biosynthesis

(2008) Benjamin Philmus et al.   CHEMBIOCHEM