Cellulonodin-2 and Lihuanodin: Lasso Peptides with an Aspartimide Post-Translational Modification

Prevention of aspartimide formation during peptide synthesis using cyanosulfurylides as carboxylic acid-protecting groups

(2020) Kevin Neumann et al.   Nature Communications

CanE, an Iron/2-Oxoglutarate-Dependent Lasso Peptide Hydroxylase from Streptomyces canus

(2020) Chen Zhang et al.   ACS Chemical Biology

Naturally Occurring Oxazole-Containing Peptides

(2020) Jessica T. Mhlongo et al.   Marine Drugs

Reactivity-Based Screening for Citrulline-Containing Natural Products Reveals a Family of Bacterial Peptidyl Arginine Deiminases

(2020) Lonnie A. Harris et al.   ACS Chemical Biology

Discovery and characterization of a novel C-terminal peptide carboxyl methyltransferase in a lassomycin-like lasso peptide biosynthetic pathway

(2019) Yu Su et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Factors Governing the Thermal Stability of Lasso Peptides

(2019) Julian D. Hegemann   CHEMBIOCHEM

Genome mining for lasso peptides: past, present, and future

(2019) Wai Ling Cheung-Lee et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

O-Methyltransferase-mediated Incorporation of a β-Amino Acid in Lanthipeptides

(2019) Jeella Z. Acedo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Pandonodin: A Proteobacterial Lasso Peptide with an Exceptionally Long C-Terminal Tail

(2019) Wai Ling Cheung-Lee et al.   ACS Chemical Biology

The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways

(2019) Rémi Zallot et al.   BIOCHEMISTRY

Discovery of ubonodin, an antimicrobial lasso peptide active against members of the Burkholderia cepacia complex

(2019) Wai Ling Cheung-Lee et al.   CHEMBIOCHEM

Biosynthetic Gene Cluster of a D-Tryptophan-Containing Lasso Peptide, MS-271

(2018) Zhi Feng et al.   CHEMBIOCHEM

Albusnodin: an acetylated lasso peptide from Streptomyces albus

(2018) Chuhan Zong et al.   CHEMICAL COMMUNICATIONS

Oxazolidinone-Mediated Sequence Determination of One-Bead One-Compound Cyclic Peptide Libraries

(2018) Hader E. Elashal et al.   ORGANIC LETTERS

Enzymatic Reconstitution and Biosynthetic Investigation of the Lasso Peptide Fusilassin

(2018) Adam J. DiCaprio et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Heterologous and in Vitro Reconstitution of Fuscanodin, a Lasso Peptide from Thermobifida fusca

(2018) Joseph D. Koos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A genetics-free method for high-throughput discovery of cryptic microbial metabolites

(2018) Fei Xu et al.   Nature Chemical Biology

Lasso Peptide Benenodin-1 Is a Thermally Actuated [1]Rotaxane Switch

(2017) Chuhan Zong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3

(2016) Caitlin D. Allen et al.   ACS Chemical Biology

Structure and Mechanism of the Sphingopyxin I Lasso Peptide Isopeptidase

(2016) Christopher D. Fage et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Insights into the Unique Phosphorylation of the Lasso Peptide Paeninodin

(2016) Shaozhou Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lasso Peptide Biosynthetic Protein LarB1 Binds Both Leader and Core Peptide Regions of the Precursor Protein LarA

(2016) Wai Ling Cheung et al.   ACS Central Science

Lasso Peptides: An Intriguing Class of Bacterial Natural Products

(2015) Julian D. Hegemann et al.   ACCOUNTS OF CHEMICAL RESEARCH

Characterization of Sviceucin from Streptomyces Provides Insight into Enzyme Exchangeability and Disulfide Bond Formation in Lasso Peptides

(2015) Yanyan Li et al.   ACS Chemical Biology

Insights from 20 years of bacterial genome sequencing

(2015) Miriam Land et al.   FUNCTIONAL & INTEGRATIVE GENOMICS

I-TASSER server: new development for protein structure and function predictions

(2015) Jianyi Yang et al.   NUCLEIC ACIDS RESEARCH

Lassomycin, a Ribosomally Synthesized Cyclic Peptide, Kills Mycobacterium tuberculosis by Targeting the ATP-Dependent Protease ClpC1P1P2

(2014) Ekaterina Gavrish et al.   CHEMISTRY & BIOLOGY

Detection and Quantitation of Succinimide in Intact Protein via Hydrazine Trapping and Chemical Derivatization

(2014) Joshua J. Klaene et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Structure, function, and biosynthesis of thiazole/oxazole-modified microcins

(2014) M. V. Metelev et al.   MOLECULAR BIOLOGY

Lasso peptides from proteobacteria: Genome mining employing heterologous expression and mass spectrometry

(2013) Julian D. Hegemann et al.   BIOPOLYMERS

Prospecting genomes for lasso peptides

(2013) Mikhail O. Maksimov et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Discovery and Characterization of an Isopeptidase That Linearizes Lasso Peptides

(2013) Mikhail O. Maksimov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lihuaxuella thermophila gen. nov., sp. nov., isolated from a geothermal soil sample in Tengchong, Yunnan, south-west China

(2012) Tian-Tian Yu et al.   ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY

Molecular cloning of the gene cluster for lariatin biosynthesis of Rhodococcus jostii K01-B0171

(2012) Junji Inokoshi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Dissecting the Maturation Steps of the Lasso Peptide Microcin J25 in vitro

(2012) Kok-Phen Yan et al.   CHEMBIOCHEM

Caulosegnins I–III: A Highly Diverse Group of Lasso Peptides Derived from a Single Biosynthetic Gene Cluster

(2012) Julian D. Hegemann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

(2012) Paul G. Arnison et al.   NATURAL PRODUCT REPORTS

Precursor-centric genome-mining approach for lasso peptide discovery

(2012) M. O. Maksimov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Construction of a Single Polypeptide that Matures and Exports the Lasso Peptide Microcin J25

(2011) Si Jia Pan et al.   CHEMBIOCHEM

The role of a conserved threonine residue in the leader peptide of lasso peptide precursors

(2011) Si Jia Pan et al.   CHEMICAL COMMUNICATIONS

New Binding Modes of 1-Acetyl- and 1-Benzoyl-5-hydroxypyrazolines - Synthesis and Characterization of O,O′-Pyrazoline- and N,O-Pyrazoline-Zinc Complexes

(2011) Chika I. Someya et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

A mass spectrometry–guided genome mining approach for natural product peptidogenomics

(2011) Roland D Kersten et al.   Nature Chemical Biology

Follow the leader: the use of leader peptides to guide natural product biosynthesis

(2009) Trent J Oman et al.   Nature Chemical Biology

MEME SUITE: tools for motif discovery and searching

(2009) T. L. Bailey et al.   NUCLEIC ACIDS RESEARCH

Isolation and Structural Characterization of Capistruin, a Lasso Peptide Predicted from the Genome Sequence of Burkholderia thailandensis E264

(2008) Thomas A. Knappe et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY