Structural insights and shedding light on preferential interactions of dietary flavonoids with G-quadruplex DNA structures: A new horizon

Therapeutic potential of flavonoids in cancer: ROS-mediated mechanisms

(2022) Hasan Slika et al.   BIOMEDICINE & PHARMACOTHERAPY

Recent Development of Flavonoids with Various Activities

(2022) Zhi-Gang Sun et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Anti‐tumoural activity of the G‐quadruplex ligand pyridostatin against BRCA1/2‐deficient tumours

(2022) Florian J Groelly et al.   EMBO Molecular Medicine

Plant flavonoids: Classification, distribution, biosynthesis, and antioxidant activity

(2022) Nan Shen et al.   FOOD CHEMISTRY

Fisetin attenuates renal ischemia/reperfusion injury by improving mitochondrial quality, reducing apoptosis and oxidative stress

(2022) Priyanka N. Prem et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Structure‐based discovery of Licoflavone B and Ginkgetin targeting c‐Myc G‐quadruplex to suppress c‐Myc transcription and myeloma growth

(2022) Linlin Liu et al.   Chemical Biology & Drug Design

Insights into the Pharmacological Effects of Flavonoids: The Systematic Review of Computer Modeling

(2022) Amir Taldaev et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Health Benefits of Quercetin in Age-Related Diseases

(2022) Deepika et al.   MOLECULES

Exploring the Parallel G-Quadruplex Nucleic Acid World: A Spectroscopic and Computational Investigation on the Binding of the c-myc Oncogene NHE III1 Region by the Phytochemical Polydatin

(2022) Francesca Greco et al.   MOLECULES

Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes

(2022) Victoria Sanchez-Martin et al.   Cancers

Recent advances in dietary flavonoids for management of type 2 diabetes

(2022) Jianbo Xiao   Current Opinion in Food Science

G-Quadruplex-Binding Proteins: Promising Targets for Drug Design

(2022) Huiling Shu et al.   Biomolecules

Chemical Structure, Sources and Role of Bioactive Flavonoids in Cancer Prevention: A Review

(2022) Georgiana Drețcanu et al.   Plants-Basel

Major Achievements in the Design of Quadruplex-Interactive Small Molecules

(2022) Eduarda Mendes et al.   Pharmaceuticals

Effects of G-Quadruplex-Binding Plant Secondary Metabolites on c-MYC Expression

(2022) Roman G. Zenkov et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Molecular encapsulation by eosin yellow-β-cyclodextrin conjugate: Differential binding to quadruplex and duplex DNA

(2022) Suganthi Soundarapandian et al.   JOURNAL OF MOLECULAR STRUCTURE

Improving All-Atom Force Field to Accurately Describe DNA G-Quadruplex Loops

(2022) Hyeonjun Kim et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Drug discovery of small molecules targeting the higher-order hTERT promoter G-quadruplex

(2022) Robert C. Monsen et al.   PLoS One

Phen‐DC 3 Induces Refolding of Human Telomeric DNA into a Chair‐Type Antiparallel G‐Quadruplex through Ligand Intercalation

(2022) Anirban Ghosh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

G-Quadruplex selectivity and cytotoxicity of a guanidine-encapsulated porphyrin-cyclodextrin conjugate

(2022) Aleyamma Alexander et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Citrus flavonoids and their antioxidant evaluation

(2021) Yue Wang et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Metal complexes as optical probes for DNA sensing and imaging

(2021) Jessica Berrones Reyes et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Gallic acid suppresses colon cancer proliferation by inhibiting SRC and EGFR phosphorylation

(2021) Xiaoming Lin et al.   Experimental and Therapeutic Medicine

Frontiers in G‐Quadruplex Therapeutics in Cancer: Selection of Small Molecules, Peptides and Aptamers

(2021) Nilanjan Banerjee et al.   Chemical Biology & Drug Design

Spectroscopic and molecular docking studies for the binding and interaction aspects of curcumin-cysteine conjugate and rosmarinic acid with human telomeric G-quadruplex DNA

(2021) Awadesh Dwivedi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

The Importance of Flavonoids and Phytochemicals of Medicinal Plants with Antiviral Activities

(2021) Mohamad Hesam Shahrajabian et al.   MINI-REVIEWS IN ORGANIC CHEMISTRY

Mass Spectrometry of Nucleic Acid Noncovalent Complexes

(2021) Eric Largy et al.   CHEMICAL REVIEWS

Recent progress in metal-based molecular probes for optical bioimaging and biosensing

(2021) Yingying Ning et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

3D‐QSAR, molecular docking, molecular dynamics, and ADME/T analysis of marketed and newly designed flavonoids as inhibitors of Bcl‐2 family proteins for targeting U‐87 glioblastoma

(2021) Alireza Poustforoosh et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

G-quadruplex in cancer biology and drug discovery

(2020) Chuya Nakanishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

A review on anti-cancer properties of Quercetin in breast cancer

(2020) Maryam Ezzati et al.   LIFE SCIENCES

Comprehensive study of the interaction between Puerariae Radix flavonoids and DNA: From theoretical simulation to structural analysis to functional analysis

(2020) Xu Chen et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Curcumin analogs exhibit anti-cancer activity by selectively targeting G-quadruplex forming c-myc promoter sequence

(2020) Nirali Pandya et al.   BIOCHIMIE

Small Molecule Fluorescent Probes for G- Quadruplex Visualization as Potential Cancer Theranostic Agents

(2019) Pallavi Chilka et al.   MOLECULES

Structural insights into the anti-cancer activity of quercetin on G-tetrad, mixed G-tetrad, and G-quadruplex DNA using quantum chemical and molecular dynamics simulations

(2019) S. Vinnarasi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Molecular encapsulation of berberine by a modified β-cyclodextrin and binding of host: guest complex to G-quadruplex DNA

(2019) Soundrapandian Suganthi et al.   NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS

Modulation of DNA structure formation using small molecules

(2019) Imee M.A. del Mundo et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Understanding biochemistry: structure and function of nucleic acids

(2019) Steve Minchin et al.   Essays in Biochemistry

Evidence on selective binding to G-quadruplex DNA of isoflavones from Maclura pomifera by mass spectrometry and molecular docking

(2019) Giovanni Ribaudo et al.   NATURAL PRODUCT RESEARCH

Metal complexes promoting catalytic cleavage of nucleic acids — biochemical tools and therapeutics

(2018) Zhen Yu et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Importance of the hydroxyl substituents in the B–ring of plant flavonols on their preferential binding interactions with VEGF G–quadruplex DNA: Multi-spectroscopic and molecular modeling studies

(2018) Snehasish Bhattacharjee et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

G-quadruplexes and G-quadruplex ligands: targets and tools in antiviral therapy

(2018) Emanuela Ruggiero et al.   NUCLEIC ACIDS RESEARCH

Study on the interaction of fisetholz with BSA/HSA by multi-spectroscopic, cyclic voltammetric and molecular docking technique

(2018) Jun Wu et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Structural basis of G-quadruplex unfolding by the DEAH/RHA helicase DHX36

(2018) Michael C. Chen et al.   NATURE

Case studies on potential G-quadruplex-forming sequences from the bacterial orders Deinococcales and Thermales derived from a survey of published genomes

(2018) Yun Ding et al.   Scientific Reports

3′ UTR G-quadruplexes regulate miRNA binding

(2017) Samuel Rouleau et al.   RNA

Exploring the preferential interaction of quercetin with VEGF promoter G-quadruplex DNA and construction of a pH-dependent DNA-based logic gate

(2017) Snehasish Bhattacharjee et al.   RSC Advances

Structural insight for the recognition of G-quadruplex structure at human c-myc promoter sequence by flavonoid Quercetin

(2017) Arpita Tawani et al.   Scientific Reports

Interaction between G-Quadruplex and Zinc Cationic Porphyrin: The Role of the Axial Water

(2017) Xiangzi Yao et al.   Scientific Reports

Computational and Experimental Characterization of Ribosomal DNA and RNA G-Quadruplexes

(2016) Samuel S. Cho   BIOPHYSICAL JOURNAL

Toward the Development of Specific G-Quadruplex Binders: Synthesis, Biophysical, and Biological Studies of New Hydrazone Derivatives

(2016) Jussara Amato et al.   JOURNAL OF MEDICINAL CHEMISTRY

Exploring the Interactions of the Dietary Plant Flavonoids Fisetin and Naringenin with G-Quadruplex and Duplex DNA, Showing Contrasting Binding Behavior: Spectroscopic and Molecular Modeling Approaches

(2016) Snehasish Bhattacharjee et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Myricetin arrests human telomeric G-quadruplex structure: a new mechanistic approach as an anticancer agent

(2016) Soma Mondal et al.   Molecular BioSystems

An overview on the role of dietary phenolics for the treatment of cancers

(2016) Preethi G. Anantharaju et al.   Nutrition Journal

G-Quadruplexes Involving Both Strands of Genomic DNA Are Highly Abundant and Colocalize with Functional Sites in the Human Genome

(2016) Andrzej S Kudlicki   PLoS One

Structural Insight into the interaction of Flavonoids with Human Telomeric Sequence

(2015) Arpita Tawani et al.   Scientific Reports

G4 motifs affect origin positioning and efficiency in two vertebrate replicators

(2014) A.-L. Valton et al.   EMBO JOURNAL

Structure-based design of flavone derivatives as c-myc oncogene down-regulators

(2012) Hui Yang et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

G-quadruplex nucleic acids as therapeutic targets

(2009) Shankar Balasubramanian et al.   CURRENT OPINION IN CHEMICAL BIOLOGY