Case studies on potential G-quadruplex-forming sequences from the bacterial orders Deinococcales and Thermales derived from a survey of published genomes

G-Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy

(2018) Rafael del Villar-Guerra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5′-Untranslated Regions

(2018) Aaron M. Fleming et al.   BIOCHEMISTRY

Identification of G-quadruplex forming sequences in three manatee papillomaviruses

(2018) Maryam Zahin et al.   PLoS One

Formation and processing of DNA damage substrates for the hNEIL enzymes

(2017) Aaron M. Fleming et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sequencing the Mouse Genome for the Oxidatively Modified Base 8-Oxo-7,8-dihydroguanine by OG-Seq

(2017) Yun Ding et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The regulatory G4 motif of the Kirsten ras (KRAS) gene is sensitive to guanine oxidation: implications on transcription

(2017) Susanna Cogoi et al.   NUCLEIC ACIDS RESEARCH

Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair

(2017) Aaron M. Fleming et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-wide regulatory dynamics of G-quadruplexes in human malaria parasite Plasmodium falciparum

(2016) Deeksha Bhartiya et al.   GENOMICS

G-quadruplex structures mark human regulatory chromatin

(2016) Robert Hänsel-Hertsch et al.   NATURE GENETICS

rG4-seq reveals widespread formation of G-quadruplex structures in the human transcriptome

(2016) Chun Kit Kwok et al.   NATURE METHODS

G-quadruplexes and helicases

(2016) Oscar Mendoza et al.   NUCLEIC ACIDS RESEARCH

Re-evaluation of G-quadruplex propensity with G4Hunter

(2016) Amina Bedrat et al.   NUCLEIC ACIDS RESEARCH

RNA G-quadruplexes are globally unfolded in eukaryotic cells and depleted in bacteria

(2016) J. U. Guo et al.   SCIENCE

Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family

(2016) Aaron M. Fleming et al.   ACS Infectious Diseases

A highly conserved G-rich consensus sequence in hepatitis C virus core gene represents a new anti-hepatitis C target

(2016) S.-R. Wang et al.   Science Advances

G-quadruplex forming structural motifs in the genome of Deinococcus radiodurans and their regulatory roles in promoter functions

(2015) Swathi Kota et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

High-throughput sequencing of DNA G-quadruplex structures in the human genome

(2015) Vicki S Chambers et al.   NATURE BIOTECHNOLOGY

The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures

(2015) Jia Zhou et al.   NUCLEIC ACIDS RESEARCH

A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These “Spare Tires” Have an Evolved Function?

(2015) Aaron M. Fleming et al.   ACS Central Science

i-Motif DNA: Structure, stability and targeting with ligands

(2014) Henry A. Day et al.   BIOORGANIC & MEDICINAL CHEMISTRY

A Matter of Location: Influence of G-Quadruplexes on Escherichia coli Gene Expression

(2014) Isabelle T. Holder et al.   CHEMISTRY & BIOLOGY

Holliday junction resolution: Regulation in space and time

(2014) Joao Matos et al.   DNA REPAIR

G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD

(2014) Lucas T Gray et al.   Nature Chemical Biology

DNA Sequences That Interfere with Transcription: Implications for Genome Function and Stability

(2013) Boris P. Belotserkovskii et al.   CHEMICAL REVIEWS

One-electron oxidation reactions of purine and pyrimidine bases in cellular DNA

(2013) Jean Cadet et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements

(2013) Giulia Antoniali et al.   MOLECULAR BIOLOGY OF THE CELL

Quantitative visualization of DNA G-quadruplex structures in human cells

(2013) Giulia Biffi et al.   Nature Chemistry

Large-scale gene function analysis with the PANTHER classification system

(2013) Huaiyu Mi et al.   Nature Protocols

The G4 Genome

(2013) Nancy Maizels et al.   PLoS Genetics

Discovery of novel rules for G-quadruplex-forming sequences in plants by using bioinformatics methods

(2012) Hiro Takahashi et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

NMR spectroscopy of G-quadruplexes

(2012) Michael Adrian et al.   METHODS

Genome-wide study predicts promoter-G4 DNA motifs regulate selective functions in bacteria: radioresistance of D. radiodurans involves G4 DNA-mediated regulation

(2012) Nicolas Beaume et al.   NUCLEIC ACIDS RESEARCH

5'-UTR RNA G-quadruplexes: translation regulation and targeting

(2012) A. Bugaut et al.   NUCLEIC ACIDS RESEARCH

Topological Characterization of Nucleic Acid G-Quadruplexes by UV Absorption and Circular Dichroism

(2011) Andreas Ioannis Karsisiotis et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cruciform structures are a common DNA feature important for regulating biological processes

(2011) Václav Brázda et al.   BMC MOLECULAR BIOLOGY

Conformational changes of non-B DNA

(2011) Jungkweon Choi et al.   CHEMICAL SOCIETY REVIEWS

Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

(2011) Yan Xu   CHEMICAL SOCIETY REVIEWS

Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?

(2011) Shankar Balasubramanian et al.   NATURE REVIEWS DRUG DISCOVERY

Telomeres: protecting chromosomes against genome instability

(2010) Roderick J. O'Sullivan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

How long is too long? Effects of loop size on G-quadruplex stability

(2010) Aurore Guédin et al.   NUCLEIC ACIDS RESEARCH

The role of G-quadruplex/i-motif secondary structures as cis-acting regulatory elements

(2010) Samantha Kendrick et al.   PURE AND APPLIED CHEMISTRY

Kinetics and mechanism of K+- and Na+-induced folding of models of human telomeric DNA into G-quadruplex structures

(2008) Robert D. Gray et al.   NUCLEIC ACIDS RESEARCH