Proliferating Astrocytes in Primary Culture Do Not Depend upon Mitochondrial Respiratory Complex I Activity or Oxidative Phosphorylation

Comparable respiratory activity in attached and suspended human fibroblasts

(2022) Lucie Zdrazilova et al.   PLoS One

Brain Energy Metabolism: Astrocytes in Neurodegenerative Diseases

(2022) Zhenlei Chen et al.   CNS Neuroscience & Therapeutics

Interferon-beta induces major histocompatibility complex of class I (MHC-I) expression and a proinflammatory phenotype in cultivated human astrocytes

(2022) Raffaela Silvestre Ignarro et al.   DIFFERENTIATION

Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells

(2022) Patricia Altea-Manzano et al.   MOLECULAR CELL

Astrocyte contribution to dysfunction, risk and progression in neurodegenerative disorders

(2022) Ashley N. Brandebura et al.   NATURE REVIEWS NEUROSCIENCE

Consumption and Metabolism of Extracellular Pyruvate by Cultured Rat Brain Astrocytes

(2022) Nadine Denker et al.   NEUROCHEMICAL RESEARCH

Inhibition of mitochondrial complex III or dihydroorotate dehydrogenase (DHODH) triggers formation of poly(A)+ RNA foci adjacent to nuclear speckles following activation of ATM (ataxia telangiectasia mutated)

(2022) Shuntaro Miyake et al.   RNA Biology

Reactive astrocyte nomenclature, definitions, and future directions

(2021) Carole Escartin et al.   NATURE NEUROSCIENCE

Mitochondrial NAD(P)+ Transhydrogenase: From Molecular Features to Physiology and Disease

(2021) Annelise Francisco et al.   ANTIOXIDANTS & REDOX SIGNALING

Glucose Metabolic Dysfunction in Neurodegenerative Diseases—New Mechanistic Insights and the Potential of Hypoxia as a Prospective Therapy Targeting Metabolic Reprogramming

(2021) Rongrong Han et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Undesirable effects of chemical inhibitors of NAD(P)+ transhydrogenase on mitochondrial respiratory function

(2020) Rafaela Bicego et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Conditional ablation of reactive astrocytes to dissect their roles in spinal cord injury and repair

(2019) Yakun Gu et al.   BRAIN BEHAVIOR AND IMMUNITY

Ablation of reactive astrocytes exacerbates disease pathology in a model of Alzheimer's disease

(2019) Loukia Katsouri et al.   GLIA

Hyperglycemia Alters Astrocyte Metabolism and Inhibits Astrocyte Proliferation

(2018) Wenjun Li et al.   Aging and Disease

High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited

(2018) Juliana S. Ruas et al.   Scientific Reports

Elevated Glutamate and Glutamine Levels in the Cerebrospinal Fluid of Patients With Probable Alzheimer's Disease and Depression

(2018) Caroline Madeira et al.   Frontiers in Psychiatry

Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity

(2017) Erika Rodrigues-Silva et al.   JOURNAL OF NEURO-ONCOLOGY

Respiration-Deficient Astrocytes Survive As Glycolytic Cells In Vivo

(2017) Lotti M. Supplie et al.   JOURNAL OF NEUROSCIENCE

Mitochondria and Cancer

(2016) Sejal Vyas et al.   CELL

Underestimation of the Maximal Capacity of the Mitochondrial Electron Transport System in Oligomycin-Treated Cells

(2016) Juliana S. Ruas et al.   PLoS One

An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis

(2015) Kıvanç Birsoy et al.   CELL

Supporting Aspartate Biosynthesis Is an Essential Function of Respiration in Proliferating Cells

(2015) Lucas B. Sullivan et al.   CELL

The return of metabolism: biochemistry and physiology of the pentose phosphate pathway

(2014) Anna Stincone et al.   BIOLOGICAL REVIEWS

Glycolysis and Oxidative Phosphorylation in Neurons and Astrocytes during Network Activity in Hippocampal Slices

(2013) Anton I Ivanov et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Underestimation of the Pentose–Phosphate Pathway in Intact Primary Neurons as Revealed by Metabolic Flux Analysis

(2013) Patricia Rodriguez-Rodriguez et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Cerebrospinal fluid lactate and pyruvate concentrations and their ratio

(2012) Wan-Ming Zhang et al.   CLINICAL BIOCHEMISTRY

Oligomycin frames a common drug-binding site in the ATP synthase

(2012) J. Symersky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation

(2011) Sophia Y. Lunt et al.   Annual Review of Cell and Developmental Biology

Sweet Sixteen for ANLS

(2011) Luc Pellerin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Brain Lactate Metabolism: The Discoveries and the Controversies

(2011) Gerald A Dienel   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Oligomycin-induced Bioenergetic Adaptation in Cancer Cells with Heterogeneous Bioenergetic Organization

(2010) Wenshan Hao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pyrimidine biosynthesis links mitochondrial respiration to the p53 pathway

(2010) A. A. Khutornenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression

(2010) A. Le et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondria and reactive oxygen species

(2009) Alicia J. Kowaltowski et al.   FREE RADICAL BIOLOGY AND MEDICINE

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Origin and progeny of reactive gliosis: A source of multipotent cells in the injured brain

(2008) A. Buffo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA