Galectin-3 and Epithelial MUC1 Mucin—Interactions Supporting Cancer Development
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Galectin-3 and Epithelial MUC1 Mucin—Interactions Supporting Cancer Development
Authors
Keywords
-
Journal
Cancers
Volume 15, Issue 10, Pages 2680
Publisher
MDPI AG
Online
2023-05-10
DOI
10.3390/cancers15102680
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- MUC1: An emerging target in cancer treatment and diagnosis
- (2022) Liangliang Qing et al. BULLETIN DU CANCER
- A Sweet Warning: Mucin-Type O-Glycans in Cancer
- (2022) Yuhan Zhang et al. Cells
- Mucins as anti-cancer targets: perspectives of the glycobiologist
- (2021) Inka Brockhausen et al. GLYCOCONJUGATE JOURNAL
- The role of mucin 1 in respiratory diseases
- (2021) Beatriz Ballester et al. European Respiratory Review
- MUC1: Structure, Function, and Clinic Application in Epithelial Cancers
- (2021) Wenqing Chen et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- MUC1 is an oncoprotein with a significant role in apoptosis (Review)
- (2021) Katarzyna Supruniuk et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- Recombinant nanobody against MUC1 tandem repeats inhibits growth, invasion, metastasis, and vascularization of spontaneous mouse mammary tumors
- (2021) Parnaz Merikhian et al. Molecular Oncology
- C1GALT1 is associated with poor survival and promotes soluble Ephrin A1-mediated cell migration through activation of EPHA2 in gastric cancer
- (2020) Po-Chu Lee et al. ONCOGENE
- Tumor-associated O-glycans of MUC1: Carriers of the glyco-code and targets for cancer vaccine design
- (2020) Donella M. Beckwith et al. SEMINARS IN IMMUNOLOGY
- Multifunctional Core–Shell Glyconanoparticles for Galectin-3-Targeted, Trigger-Responsive Combination Chemotherapy
- (2020) Biji Balakrishnan et al. BIOMACROMOLECULES
- Muc1-c in chronic inflammation and carcinogenesis;emergence as a target for cancer treatment
- (2020) Donald W Kufe CARCINOGENESIS
- The expression and functional analysis of the sialyl-T antigen in prostate cancer
- (2020) Ruifeng Bai et al. GLYCOCONJUGATE JOURNAL
- Mucins in pancreatic cancer: A well‐established but promising family for diagnosis, prognosis and therapy
- (2020) Shunda Wang et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- TF-containing MUC1 glycopeptides fail to entice Galectin-1 recognition of tumor-associated Thomsen-Freidenreich (TF) antigen (CD176) in solution
- (2020) Forrest G. FitzGerald et al. GLYCOCONJUGATE JOURNAL
- Global view of human protein glycosylation pathways and functions
- (2020) Katrine T. Schjoldager et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cancer-associated mucins: role in immune modulation and metastasis
- (2019) Rakesh Bhatia et al. CANCER AND METASTASIS REVIEWS
- Mucin glycoproteins block apoptosis; promote invasion, proliferation, and migration; and cause chemoresistance through diverse pathways in epithelial cancers
- (2019) Ian S. Reynolds et al. CANCER AND METASTASIS REVIEWS
- MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells
- (2019) Hasan Rajabi et al. ONCOGENE
- Roles of galectin-3 in metabolic disorders and tumor cell metabolism
- (2019) Ying-Shuang Li et al. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
- Core 1–derived mucin-type O-glycosylation protects against spontaneous gastritis and gastric cancer
- (2019) Fei Liu et al. JOURNAL OF EXPERIMENTAL MEDICINE
- O-linked mucin-type glycosylation in breast cancer
- (2018) Joy M. Burchell et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Latest developments in MUC1 immunotherapy
- (2018) Joyce Taylor-Papadimitriou et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- “In vitro” studies on galectin-3 in human natural killer cells
- (2018) Alvaro Brittoli et al. IMMUNOLOGY LETTERS
- Galectin-3: One Molecule for an Alphabet of Diseases, from A to Z
- (2018) Salvatore Sciacchitano et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Role of Galectins in Tumors and in Clinical Immunotherapy
- (2018) Feng-Cheng Chou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Galectins as Molecular Targets for Therapeutic Intervention
- (2018) Ruud Dings et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Galectins at a glance
- (2018) Ludger Johannes et al. JOURNAL OF CELL SCIENCE
- MUC1 Mucin: A Putative Regulatory (Checkpoint) Molecule of T Cells
- (2018) Babita Agrawal et al. Frontiers in Immunology
- Dual Role of the Extracellular Domain of Human Mucin MUC1 in Metastasis
- (2017) M.S. Syrkina et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Transmembrane Mucins: Signaling Receptors at the Intersection of Inflammation and Cancer
- (2017) Jos P.M. van Putten et al. Journal of Innate Immunity
- NF-κB as the main node of resistance to receptor tyrosine kinase inhibitors in triple-negative breast cancer
- (2017) Behrad Darvishi et al. TUMOR BIOLOGY
- ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway
- (2017) Tadashi Ogawa et al. Oncotarget
- The N-terminal tail coordinates with carbohydrate recognition domain to mediate galectin-3 induced apoptosis in T cells
- (2017) Huiting Xue et al. Oncotarget
- Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives
- (2016) Joanne Chia et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Galectin 3 as a guardian of the tumor microenvironment
- (2016) Peter P. Ruvolo BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Galectin-3 Determines Tumor Cell Adaptive Strategies in Stressed Tumor Microenvironments
- (2016) Ana Carolina Ferreira Cardoso et al. Frontiers in Oncology
- Interaction of the Oncofetal Thomsen–Friedenreich Antigen with Galectins in Cancer Progression and Metastasis
- (2016) Paulina Sindrewicz et al. Frontiers in Oncology
- MUC1 as a Potential Target in Anticancer Therapies
- (2015) Krishna Pillai et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Thermodynamic Switch in Binding of Adhesion/Growth Regulatory Human Galectin-3 to Tumor-Associated TF Antigen (CD176) and MUC1 Glycopeptides
- (2015) Maria C. Rodriguez et al. BIOCHEMISTRY
- Downregulating galectin-3 inhibits proinflammatory cytokine production by human monocyte-derived dendritic cells via RNA interference
- (2015) Swey-Shen Chen et al. CELLULAR IMMUNOLOGY
- Binding of Galectin-3, a β-Galactoside-binding Lectin, to MUC1 Protein Enhances Phosphorylation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Akt, Promoting Tumor Cell Malignancy
- (2015) Yugo Mori et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Chemically modified, non-anticoagulant heparin derivatives are potent galectin-3 binding inhibitors and inhibit circulating galectin-3-promoted metastasis
- (2015) Carrie A Duckworth et al. Oncotarget
- The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
- (2015) Richard Beatson et al. PLoS One
- Galectin-3 leads to attenuation of apoptosis through Bax heterodimerization in human thyroid carcinoma cells
- (2015) Yosuke Harazono et al. Oncotarget
- Development, Characterization, and Immunotherapeutic Use of Peptide Mimics of the Thomsen-Friedenreich Carbohydrate Antigen
- (2015) Jamie Heimburg-Molinaro et al. NEOPLASIA
- Galectin-3 binds to MUC1-N-terminal domain and triggers recruitment of β-catenin in MUC1-expressing mouse 3T3 cells
- (2014) Shuhei Tanida et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- The role of galectin-3 and galectin-3-binding protein in venous thrombosis
- (2014) E. P. DeRoo et al. BLOOD
- Lactose-Functionalized Dendrimers Arbitrate the Interaction of Galectin-3/MUC1 Mediated Cancer Cellular Aggregation
- (2014) Anna K. Michel et al. CHEMBIOCHEM
- Galectin-3 in cancer
- (2014) Lin Song et al. CLINICA CHIMICA ACTA
- Intracellular galectins in cancer cells: Potential new targets for therapy
- (2014) MARIA C. VLADOIU et al. INTERNATIONAL JOURNAL OF ONCOLOGY
- MUC1: a multifaceted oncoprotein with a key role in cancer progression
- (2014) Sritama Nath et al. TRENDS IN MOLECULAR MEDICINE
- Altered Tumor-Cell Glycosylation Promotes Metastasis
- (2014) Irina Häuselmann et al. Frontiers in Oncology
- A monosaccharide-modified peptide phage library for screening of ligands to carbohydrate-binding proteins
- (2013) Kanako Arai et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Increased Circulation of Galectin-3 in Cancer Induces Secretion of Metastasis-Promoting Cytokines from Blood Vascular Endothelium
- (2013) C. Chen et al. CLINICAL CANCER RESEARCH
- Suppression of SERPINA1-albumin complex formation by galectin-3 overexpression leads to paracrine growth promotion of chronic myelogenous leukemia cells
- (2013) Ryuko Nakayama et al. LEUKEMIA RESEARCH
- Mucins in pancreatic cancer and its microenvironment
- (2013) Sukhwinder Kaur et al. Nature Reviews Gastroenterology & Hepatology
- Tn and sialyl-Tn antigens, aberrantO-glycomics as human disease markers
- (2013) Tongzhong Ju et al. Proteomics Clinical Applications
- Tumour Immunomodulation: Mucins in Resistance to Initiation and Maturation of Immune Response Against Tumours
- (2013) A. AnandKumar et al. SCANDINAVIAN JOURNAL OF IMMUNOLOGY
- Molecular Recognition of the Thomsen-Friedenreich Antigen–Threonine Conjugate by Adhesion/Growth Regulatory Galectin-3: Nuclear Magnetic Resonance Studies and Molecular Dynamics Simulations
- (2012) Austin B. Yongye et al. BIOCHEMISTRY
- Tight Complex Formation between Cosmc Chaperone and Its Specific Client Non-native T-synthase Leads to Enzyme Activity and Client-driven Dissociation
- (2012) Rajindra P. Aryal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tyrosine-phosphorylated Galectin-3 Protein Is Resistant to Prostate-specific Antigen (PSA) Cleavage
- (2012) Vitaly Balan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The expressions and clinical significances of tissue and serum galectin-3 in pancreatic carcinoma
- (2012) Ling Xie et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
- (2012) D W Kufe ONCOGENE
- Galectin-3 – A jack-of-all-trades in cancer
- (2011) Anna U. Newlaczyl et al. CANCER LETTERS
- Control of mucin-type O-glycosylation: A classification of the polypeptide GalNAc-transferase gene family
- (2011) E. P. Bennett et al. GLYCOBIOLOGY
- Sialylation regulates galectin-3/ligand interplay during mammary tumour progression - a case of targeted uncloaking
- (2011) Joana-Tavares de Oliveira et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- MUC1 Protein Expression in Tumor Cells Regulates Transcription of Proinflammatory Cytokines by Forming a Complex with Nuclear Factor-κB p65 and Binding to Cytokine Promoters
- (2011) Sandra Cascio et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Structural Basis for Distinct Binding Properties of the Human Galectins to Thomsen-Friedenreich Antigen
- (2011) Cheng-Feng Bian et al. PLoS One
- LPS-Induced Galectin-3 Oligomerization Results in Enhancement of Neutrophil Activation
- (2011) Marise Lopes Fermino et al. PLoS One
- Cancer Biomarkers Defined by Autoantibody Signatures to Aberrant O-Glycopeptide Epitopes
- (2010) H. H. Wandall et al. CANCER RESEARCH
- c-Abl and Arg tyrosine kinases regulate lysosomal degradation of the oncoprotein Galectin-3
- (2010) X Li et al. CELL DEATH AND DIFFERENTIATION
- Novel Interaction of MUC4 and Galectin: Potential Pathobiological Implications for Metastasis in Lethal Pancreatic Cancer
- (2010) S. Senapati et al. CLINICAL CANCER RESEARCH
- Focus on Molecules: Galectin-3
- (2010) Pablo Argüeso et al. EXPERIMENTAL EYE RESEARCH
- Serum levels of galectin-3 and its ligand 90k/mac-2bp in colorectal cancer patients
- (2010) Palma A. Iacovazzi et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Interaction between circulating galectin-3 and cancer-associated MUC1 enhances tumour cell homotypic aggregation and prevents anoikis
- (2010) Qicheng Zhao et al. Molecular Cancer
- Membrane-bound mucins: the mechanistic basis for alterations in the growth and survival of cancer cells
- (2010) S Bafna et al. ONCOGENE
- Cosmc is an essential chaperone for correct protein O-glycosylation
- (2010) Y. Wang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dynamics of galectin-3 in the nucleus and cytoplasm
- (2009) Kevin C. Haudek et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor
- (2009) R. Ahmad et al. CANCER RESEARCH
- Circulating Galectin-3 Promotes Metastasis by Modifying MUC1 Localization on Cancer Cell Surface
- (2009) Q. Zhao et al. CANCER RESEARCH
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- The Endoplasmic Reticulum Chaperone Cosmc Directly Promotesin VitroFolding of T-synthase
- (2009) Rajindra P. Aryal et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MUC1 Oncoprotein Blocks Death Receptor-Mediated Apoptosis by Inhibiting Recruitment of Caspase-8
- (2008) N. Agata et al. CANCER RESEARCH
- Galectins: structure, function and therapeutic potential
- (2008) Ri-Yao Yang et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- Arginine Binding Motifs: Design and Synthesis of Galactose-Derived Arginine Tweezers as Galectin-3 Inhibitors
- (2008) Christopher T. Öberg et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Cytoplasmic Tail of MUC1: A Very Busy Place
- (2008) D. D. Carson Science Signaling
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started