MUC1-C represses the RASSF1A tumor suppressor in human carcinoma cells

RASSF1A Deficiency Enhances RAS-Driven Lung Tumorigenesis

(2018) M. Lee Schmidt et al.   CANCER RESEARCH

Rational Approaches for Combination Therapy Strategies Targeting the MAP Kinase Pathway in Solid Tumors

(2018) Anthony W. Tolcher et al.   MOLECULAR CANCER THERAPEUTICS

MUC1-C activates polycomb repressive complexes and downregulates tumor suppressor genes in human cancer cells

(2018) Hasan Rajabi et al.   ONCOGENE

ERK1/2 inhibitors: New weapons to inhibit the RAS-regulated RAF-MEK1/2-ERK1/2 pathway

(2018) Andrew M. Kidger et al.   PHARMACOLOGY & THERAPEUTICS

RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73

(2018) Angelos Papaspyropoulos et al.   Nature Communications

KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism

(2018) Angelina V. Vaseva et al.   CANCER CELL

Impact of Natural Compounds on DNA Methylation Levels of the Tumor Suppressor Gene RASSF1A in Cancer

(2017) Reinhard Dammann et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ZEB1 confers stem cell-like properties in breast cancer by targeting neurogenin-3

(2017) Chen Zhou et al.   Oncotarget

MUC1-C activates EZH2 expression and function in human cancer cells

(2017) Hasan Rajabi et al.   Scientific Reports

Inhibition of MUC1-C Suppresses MYC Expression and Attenuates Malignant Growth in KRAS Mutant Lung Adenocarcinomas

(2016) Audrey Bouillez et al.   CANCER RESEARCH

RASSF1A Suppresses the Invasion and Metastatic Potential of Human Non–Small Cell Lung Cancer Cells by Inhibiting YAP Activation through the GEF-H1/RhoB Pathway

(2016) Fatéméh Dubois et al.   CANCER RESEARCH

MUC1-C Represses the Crumbs Complex Polarity Factor CRB3 and Downregulates the Hippo Pathway

(2016) Maroof Alam et al.   MOLECULAR CANCER RESEARCH

MUC1-C activates BMI1 in human cancer cells

(2016) M Hiraki et al.   ONCOGENE

DNA methylation by DNMT1 and DNMT3b methyltransferases is driven by the MUC1-C oncoprotein in human carcinoma cells

(2016) H Rajabi et al.   ONCOGENE

Ras signaling through RASSF proteins

(2016) Howard Donninger et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

MUC1-C induces DNA methyltransferase 1 and represses tumor suppressor genes in acute myeloid leukemia

(2016) Ashujit Tagde et al.   Oncotarget

Alternate RASSF1 Transcripts Control SRC Activity, E-Cadherin Contacts, and YAP-Mediated Invasion

(2015) Nikola Vlahov et al.   CURRENT BIOLOGY

MUC1-C activates the TAK1 inflammatory pathway in colon cancer

(2015) H Takahashi et al.   ONCOGENE

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

RASSF1A Inactivation Unleashes a Tumor Suppressor/Oncogene Cascade with Context-Dependent Consequences on Cell Cycle Progression

(2014) R. R. Ram et al.   MOLECULAR AND CELLULAR BIOLOGY

Protein interaction switches coordinate Raf-1 and MST2/Hippo signalling

(2014) David Romano et al.   NATURE CELL BIOLOGY

Drugging the undruggable RAS: Mission Possible?

(2014) Adrienne D. Cox et al.   NATURE REVIEWS DRUG DISCOVERY

MUC1-C oncoprotein activates the ZEB1/miR-200c regulatory loop and epithelial–mesenchymal transition

(2013) H Rajabi et al.   ONCOGENE

The MUC1-C Oncoprotein Binds to the BH3 Domain of the Pro-apoptotic BAX Protein and Blocks BAX Function

(2012) Rehan Ahmad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MUC1-C Oncoprotein Induces TCF7L2 Transcription Factor Activation and Promotes Cyclin D1 Expression in Human Breast Cancer Cells

(2012) Hasan Rajabi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches

(2012) D W Kufe   ONCOGENE

Targeted Methylation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells

(2011) I.-W. Teng et al.   CANCER RESEARCH

A Monoclonal Antibody Against the Oncogenic Mucin 1 Cytoplasmic Domain

(2011) Govind Panchamoorthy et al.   HYBRIDOMA

The Tumor Suppressor RASSF1A Prevents Dephosphorylation of the Mammalian STE20-like Kinases MST1 and MST2

(2011) Cai Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras

(2011) David Matallanas et al.   MOLECULAR CELL

MUC1-C Oncoprotein Functions as a Direct Activator of the Nuclear Factor- B p65 Transcription Factor

(2009) R. Ahmad et al.   CANCER RESEARCH

RASSF1A Mediates p21Cip1/Waf1-Dependent Cell Cycle Arrest and Senescence through Modulation of the Raf-MEK-ERK Pathway and Inhibition of Akt

(2009) S. Thaler et al.   CANCER RESEARCH

Epigenetic Silencing of the RASSF1A Tumor Suppressor Gene through HOXB3-Mediated Induction of DNMT3B Expression

(2009) Rajendra Kumar Palakurthy et al.   MOLECULAR CELL