Pan-cancer genomic analysis shows hemizygous PTEN loss tumors are associated with immune evasion and poor outcome
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Title
Pan-cancer genomic analysis shows hemizygous PTEN loss tumors are associated with immune evasion and poor outcome
Authors
Keywords
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Journal
Scientific Reports
Volume 13, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-03-28
DOI
10.1038/s41598-023-31759-6
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Note: Only part of the references are listed.- Comprehensive characterization of PTEN mutational profile in a series of 34,129 colorectal cancers
- (2022) Ilya G. Serebriiskii et al. Nature Communications
- Overcoming Resistance to Immune Checkpoint Inhibitors in Head and Neck Squamous Cell Carcinomas
- (2021) Lucas V. dos Santos et al. Frontiers in Oncology
- PTEN loss correlates with T cell exclusion across human cancers
- (2021) Ziying Lin et al. BMC CANCER
- Transcriptional landscape of PTEN loss in primary prostate cancer
- (2021) Eddie Luidy Imada et al. BMC CANCER
- Recounting the FANTOM CAGEAssociated Transcriptome
- (2020) Eddie Luidy Imada et al. GENOME RESEARCH
- Pan-cancer analysis of whole genomes
- (2020) NATURE
- An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships
- (2020) Taylor L. Mighell et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Emerging role of PTEN loss in evasion of the immune response to tumours
- (2020) Thiago Vidotto et al. BRITISH JOURNAL OF CANCER
- Pathway-specific genome editing of PI3K/mTOR tumor suppressor genes reveals that PTEN loss contributes to cetuximab resistance in head and neck cancer
- (2020) Hiroki Izumi et al. MOLECULAR CANCER THERAPEUTICS
- PTEN Alterations and Their Role in Cancer Management: Are We Making Headway on Precision Medicine?
- (2020) Nicola Fusco et al. Genes
- PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?
- (2019) Chiara Bazzichetto et al. Cancers
- Mechanisms of PTEN loss in cancer: It’s all about diversity
- (2019) Virginia Álvarez-Garcia et al. SEMINARS IN CANCER BIOLOGY
- Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
- (2019) Junfei Zhao et al. NATURE MEDICINE
- miR-96-5p targets PTEN expression affecting radio-chemosensitivity of HNSCC cells
- (2019) Mahrou Vahabi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma
- (2019) Caibin Fan et al. Frontiers in Oncology
- Precise Immunodetection of PTEN Protein in Human Neoplasia
- (2019) Rafael Pulido et al. Cold Spring Harbor Perspectives in Medicine
- Multifaceted Regulation of PTEN Subcellular Distributions and Biological Functions
- (2019) Tian Liu et al. Cancers
- Copy number variation is highly correlated with differential gene expression: a pan-cancer study
- (2019) Xin Shao et al. BMC Medical Genetics
- Structural Mechanisms of PTEN Regulation
- (2019) Glenn R. Masson et al. Cold Spring Harbor Perspectives in Medicine
- Identification of key pathways and genes in PTEN mutation prostate cancer by bioinformatics analysis
- (2019) Jian Sun et al. BMC Medical Genetics
- The Immune Landscape of Cancer
- (2018) Vésteinn Thorsson et al. IMMUNITY
- Cancer-Cell-Intrinsic Mechanisms Shaping the Tumor Immune Landscape
- (2018) Max D. Wellenstein et al. IMMUNITY
- Diverse genetic-driven immune landscapes dictate tumor progression through distinct mechanisms
- (2018) Marco Bezzi et al. NATURE MEDICINE
- The functions and regulation of the PTEN tumour suppressor: new modes and prospects
- (2018) Yu-Ru Lee et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Clinical implications of PTEN loss in prostate cancer
- (2018) Tamara Jamaspishvili et al. Nature Reviews Urology
- Distinct subtypes of genomic PTEN deletion size influence the landscape of aneuploidy and outcome in prostate cancer
- (2018) Thiago Vidotto et al. Molecular Cytogenetics
- Genomic Deletion at 10q23 in Prostate Cancer: More Than PTEN Loss?
- (2018) Raghavendra Tejo Karthik Poluri et al. Frontiers in Oncology
- Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences
- (2018) Anqi Zhu et al. BIOINFORMATICS
- Reproducible RNA-seq analysis using recount2
- (2017) Leonardo Collado-Torres et al. NATURE BIOTECHNOLOGY
- Control of PD-L1 Expression by Oncogenic Activation of the AKT–mTOR Pathway in Non–Small Cell Lung Cancer
- (2015) Kristin J. Lastwika et al. CANCER RESEARCH
- Robust enumeration of cell subsets from tissue expression profiles
- (2015) Aaron M Newman et al. NATURE METHODS
- The Molecular Signatures Database Hallmark Gene Set Collection
- (2015) Arthur Liberzon et al. Cell Systems
- Can we accurately report PTEN status in advanced colorectal cancer?
- (2014) Christopher Hocking et al. BMC CANCER
- Complete Loss of PTEN Protein Expression Correlates with Shorter Time to Brain Metastasis and Survival in Stage IIIB/C Melanoma Patients with BRAFV600 Mutations
- (2014) A. D. Bucheit et al. CLINICAL CANCER RESEARCH
- Low PTEN expression is associated with worse overall survival in head and neck squamous cell carcinoma patients treated with chemotherapy and cetuximab
- (2014) Alexandre A. B. A. da Costa et al. International Journal of Clinical Oncology
- The PTEN/PI3K/AKT Pathway in vivo, Cancer Mouse Models
- (2014) Amancio Carnero et al. Frontiers in Oncology
- The Somatic Genomic Landscape of Glioblastoma
- (2013) Cameron W. Brennan et al. CELL
- Pan-cancer patterns of somatic copy number alteration
- (2013) Travis I Zack et al. NATURE GENETICS
- PTEN Loss Increases PD-L1 Protein Expression and Affects the Correlation between PD-L1 Expression and Clinical Parameters in Colorectal Cancer
- (2013) Minmin Song et al. PLoS One
- Absolute quantification of somatic DNA alterations in human cancer
- (2012) Scott L Carter et al. NATURE BIOTECHNOLOGY
- Reduction ofPtendose leads to neoplastic development in multiple organs ofPtenshRNAmice
- (2011) Hong Shen-Li et al. CANCER BIOLOGY & THERAPY
- PTEN Level in Tumor Suppression: How Much Is Too Little?
- (2011) A. Carracedo et al. CANCER RESEARCH
- PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplications
- (2011) Maisa Yoshimoto et al. GENES CHROMOSOMES & CANCER
- The genomic complexity of primary human prostate cancer
- (2011) Michael F. Berger et al. NATURE
- Loss of TGF-β signaling and PTEN promotes head and neck squamous cell carcinoma through cellular senescence evasion and cancer-related inflammation
- (2011) Y Bian et al. ONCOGENE
- GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers
- (2011) Craig H Mermel et al. GENOME BIOLOGY
- Signatures of mutation and selection in the cancer genome
- (2010) Graham R. Bignell et al. NATURE
- Subtle variations in Pten dose determine cancer susceptibility
- (2010) Andrea Alimonti et al. NATURE GENETICS
- Mutational Heterogeneity in Human Cancers: Origin and Consequences
- (2009) Jesse J. Salk et al. Annual Review of Pathology-Mechanisms of Disease
- PTENgenomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer
- (2009) Kanishka Sircar et al. JOURNAL OF PATHOLOGY
- PTEN and the PI3-Kinase Pathway in Cancer
- (2008) Nader Chalhoub et al. Annual Review of Pathology-Mechanisms of Disease
- Loss of PTEN expression is associated with colorectal cancer liver metastasis and poor patient survival
- (2008) Hirozumi Sawai et al. BMC GASTROENTEROLOGY
- Pten Haploinsufficiency Accelerates Formation of High-Grade Astrocytomas
- (2008) C.-H. Kwon et al. CANCER RESEARCH
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