PTEN genomic deletions that characterize aggressive prostate cancer originate close to segmental duplications

Recurrent RECQL4 Imbalance and Increased Gene Expression Levels Are Associated with Structural Chromosomal Instability in Sporadic Osteosarcoma

(2015) Georges Maire et al.   NEOPLASIA

Prostate cancer genomic signature offers prognostic value

(2011) Sarah M. Troutman et al.   CANCER BIOLOGY & THERAPY

Detection ofERGgene rearrangements andPTENdeletions in unsuspected prostate cancer of the transition zone

(2011) Shuhong Liu et al.   CANCER BIOLOGY & THERAPY

PTEN Level in Tumor Suppression: How Much Is Too Little?

(2011) A. Carracedo et al.   CANCER RESEARCH

The phenotype of recurrent 10q22q23 deletions and duplications

(2011) Bregje W M van Bon et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Observation and prediction of recurrent human translocations mediated by NAHR between nonhomologous chromosomes

(2011) Z. Ou et al.   GENOME RESEARCH

Transcriptional consequences of genomic structural aberrations in breast cancer

(2011) K. Inaki et al.   GENOME RESEARCH

The genomic complexity of primary human prostate cancer

(2011) Michael F. Berger et al.   NATURE

Array CGH as a potential predictor of radiocurability in intermediate risk prostate cancer

(2010) Adrian S. Ishkanian et al.   ACTA ONCOLOGICA

Identification of a Recurrent Microdeletion at 17q23.1q23.2 Flanked by Segmental Duplications Associated with Heart Defects and Limb Abnormalities

(2010) Blake C. Ballif et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genomic and clinical characteristics of microduplications in chromosome 17

(2010) Oleg A. Shchelochkov et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

PTEN genomic deletion is an early event associated with ERG gene rearrangements in prostate cancer

(2010) Tarek A. Bismar et al.   BJU INTERNATIONAL

Molecular characterisation of ERG, ETV1 and PTEN gene loci identifies patients at low and high risk of death from prostate cancer

(2010) A H M Reid et al.   BRITISH JOURNAL OF CANCER

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

SOX9 Elevation in the Prostate Promotes Proliferation and Cooperates with PTEN Loss to Drive Tumor Formation

(2010) M. K. Thomsen et al.   CANCER RESEARCH

BRCA1 Loss Preexisting in Small Subpopulations of Prostate Cancer Is Associated with Advanced Disease and Metastatic Spread to Lymph Nodes and Peripheral Blood

(2010) N. Bednarz et al.   CLINICAL CANCER RESEARCH

Analysis of Segmental Duplications, Mouse Genome Synteny and Recurrent Cancer-Associated Amplicons in Human Chromosome 6p21–p12

(2010) J.W. Martin et al.   CYTOGENETIC AND GENOME RESEARCH

Frequent Gastrointestinal Polyps and Colorectal Adenocarcinomas in a Prospective Series of PTEN Mutation Carriers

(2010) Brandie Heald et al.   GASTROENTEROLOGY

Molecular genetics of prostate cancer: new prospects for old challenges

(2010) M. M. Shen et al.   GENES & DEVELOPMENT

Deletion and duplication of 15q24: Molecular mechanisms and potential modification by additional copy number variants

(2010) Ayman W El-Hattab et al.   GENETICS IN MEDICINE

Possible involvement of loss of heterozygosity in malignant transformation of ovarian endometriosis

(2010) Bing Xu et al.   GYNECOLOGIC ONCOLOGY

Resveratrol regulates the PTEN/AKT pathway through androgen receptor-dependent and -independent mechanisms in prostate cancer cell lines

(2010) Yu Wang et al.   HUMAN MOLECULAR GENETICS

A novel third type of recurrent NF1 microdeletion mediated by nonallelic homologous recombination between LRRC37B-containing low-copy repeats in 17q11.2

(2010) Kathrin Bengesser et al.   HUMAN MUTATION

Molecular alterations of EGFR and PTEN in prostate cancer: association with high-grade and advanced-stage carcinomas

(2010) Silvia de Muga et al.   MODERN PATHOLOGY

Low-copy repeats on chromosome 22q11.2 show replication timing switches, DNA flexibility peaks and stress inducible asynchrony, sharing instability features with fragile sites

(2010) Aldamaria Puliti et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Subtle variations in Pten dose determine cancer susceptibility

(2010) Andrea Alimonti et al.   NATURE GENETICS

Segmental duplications in the human genome reveal details of pseudogene formation

(2010) Ekta Khurana et al.   NUCLEIC ACIDS RESEARCH

Genomic segmental duplications on the basis of the t(9;22) rearrangement in chronic myeloid leukemia

(2010) F Albano et al.   ONCOGENE

Genomic rearrangements in inherited disease and cancer

(2010) Jian-Min Chen et al.   SEMINARS IN CANCER BIOLOGY

Coalterations of p53 and PTEN tumor suppressor genes in non–small cell lung carcinoma patients

(2010) Tijana Andjelkovic et al.   Translational Research

Comparative Analyses of Chromosome Alterations in Soft-Tissue Metastases within and across Patients with Castration-Resistant Prostate Cancer

(2009) I. N. Holcomb et al.   CANCER RESEARCH

Nuclear Receptor-Induced Chromosomal Proximity and DNA Breaks Underlie Specific Translocations in Cancer

(2009) Chunru Lin et al.   CELL

Targeting the PI3K/AKT Pathway for the Treatment of Prostate Cancer

(2009) D. Sarker et al.   CLINICAL CANCER RESEARCH

Duplication hotspots, rare genomic disorders, and common disease

(2009) Heather C Mefford et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

PTENgenomic deletion is associated with p-Akt and AR signalling in poorer outcome, hormone refractory prostate cancer

(2009) Kanishka Sircar et al.   JOURNAL OF PATHOLOGY

TMPRSS2-ERG and PTEN loss in prostate cancer

(2009) Jeremy A Squire   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

Copy number analysis indicates monoclonal origin of lethal metastatic prostate cancer

(2009) Wennuan Liu et al.   NATURE MEDICINE

High-resolution array CGH identifies novel regions of genomic alteration in intermediate-risk prostate cancer

(2009) Adrian S. Ishkanian et al.   PROSTATE

Induced Chromosomal Proximity and Gene Fusions in Prostate Cancer

(2009) R.-S. Mani et al.   SCIENCE

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation

(2009) P. J. Hastings et al.   PLoS Genetics

Molecular Alterations in Prostate Cancer as Diagnostic, Prognostic, and Therapeutic Targets

(2008) Bora Gurel et al.   ADVANCES IN ANATOMIC PATHOLOGY

Distal 22q11.2 microduplication encompassing theBCRgene

(2008) Maria Descartes et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Emerging Biomarkers for the Diagnosis and Prognosis of Prostate Cancer

(2008) G. Sardana et al.   CLINICAL CHEMISTRY

Identification of human haploinsufficient genes and their genomic proximity to segmental duplications

(2008) Vinh T Dang et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Absence of TMPRSS2:ERG fusions and PTEN losses in prostate cancer is associated with a favorable outcome

(2008) Maisa Yoshimoto et al.   MODERN PATHOLOGY

PCR-SSCP-DNA sequencing method in detecting PTEN gene mutation and its significance in human gastric cancer

(2008) Chuan-Yong Guo et al.   WORLD JOURNAL OF GASTROENTEROLOGY