Peptide Backbone Composition and Protease Susceptibility: Impact of Modification Type, Position, and Tandem Substitution

Modulating protein–protein interactions: the potential of peptides

(2015) Laura Nevola et al.   CHEMICAL COMMUNICATIONS

Folding and function in α/β-peptides: targets and therapeutic applications

(2015) Halina M Werner et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Hot spot-based design of small-molecule inhibitors for protein–protein interactions

(2014) Wenxing Guo et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Peptidomimetics via modifications of amino acids and peptide bonds

(2014) Ilker Avan et al.   CHEMICAL SOCIETY REVIEWS

Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality

(2014) Michelle R. Arkin et al.   CHEMISTRY & BIOLOGY

Peptides Containing β-Amino Acid Patterns: Challenges and Successes in Medicinal Chemistry

(2014) Chiara Cabrele et al.   JOURNAL OF MEDICINAL CHEMISTRY

Protein backbone engineering as a strategy to advance foldamers toward the frontier of protein-like tertiary structure

(2014) Zachary E. Reinert et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Folding thermodynamics of protein-like oligomers with heterogeneous backbones

(2014) Zachary E. Reinert et al.   Chemical Science

Pharmacokinetics and Pharmacokinetic–Pharmacodynamic Correlations of Therapeutic Peptides

(2013) Lei Diao et al.   CLINICAL PHARMACOKINETICS

Protein-like Tertiary Folding Behavior from Heterogeneous Backbones

(2013) Zachary E. Reinert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

N-Methylation of Peptides and Proteins: An Important Element for Modulating Biological Functions

(2012) Jayanta Chatterjee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Protease-resistant peptide design-empowering nature's fragile warriors against HIV

(2012) Matthew T. Weinstock et al.   BIOPOLYMERS

Design Strategies for the Sequence-Based Mimicry of Side-Chain Display in Protein β-Sheets by α/β-Peptides

(2012) George A. Lengyel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phage selection of cyclic peptide antagonists with increased stability toward intestinal proteases

(2012) V. Baeriswyl et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Cellular uptake of Aib-containing amphipathic helix peptide

(2011) Shun-ichi Wada et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Synthetic foldamers

(2011) Gilles Guichard et al.   CHEMICAL COMMUNICATIONS

Peptide and peptoid foldamers in medicinal chemistry

(2011) W Seth Horne   Expert Opinion on Drug Discovery

Molecular Recognition of Chymotrypsin by the Serine Protease Inhibitor Ecotin fromYersinia pestis

(2011) Elizabeth A. Clark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discovery and characterization of taspoglutide, a novel analogue of human glucagon-like peptide-1, engineered for sustained therapeutic activity in type 2 diabetes

(2010) J. Z. Dong et al.   DIABETES OBESITY & METABOLISM

The Propensity of α-Aminoisobutyric Acid (=2-Methylalanine; Aib) to Induce Helical Secondary Structure in an α-Heptapeptide: A Computational Study

(2010) Dongqi Wang et al.   HELVETICA CHIMICA ACTA

Peptide drugs to target G protein-coupled receptors

(2010) Kathrin Bellmann-Sickert et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

To protect peptide pharmaceuticals against peptidases

(2010) R. Rink et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Development and Characterization of Peptidic Fusion Inhibitors Derived from HIV-1 gp41 with Partial D-Amino Acid Substitutions

(2009) Fabrice Gaston et al.   ChemMedChem

The Medicinal Chemistry of Peptides

(2009) J. Nestor Jr.   CURRENT MEDICINAL CHEMISTRY

Advances in Peptide Pharmaceuticals

(2009) Cynthia Stevenson   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

β-Peptidic Peptidomimetics

(2008) Dieter Seebach et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Methyl Scanning Mutagenesis Generates Protease-Resistant G Protein Ligands with Improved Affinity and Selectivity

(2008) Stephen V. Fiacco et al.   CHEMBIOCHEM

The Crystal Structure of Guamerin in Complex with Chymotrypsin and the Development of an Elastase-specific Inhibitor

(2007) Hun Kim et al.   JOURNAL OF MOLECULAR BIOLOGY