Tangzhiqing-mediated NRF2 reduces autophagy-dependent ferroptosis to mitigate diabetes-related cognitive impairment neuronal damage

Enhanced defense against ferroptosis ameliorates cognitive impairment and reduces neurodegeneration in 5xFAD mice

(2022) Liuji Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Caveolin-1 Alleviates Diabetes-Associated Cognitive Dysfunction Through Modulating Neuronal Ferroptosis-Mediated Mitochondrial Homeostasis

(2022) Wenxin Tang et al.   ANTIOXIDANTS & REDOX SIGNALING

High glucose-induced ROS-accumulation in embryo-larval stages of zebrafish leads to mitochondria-mediated apoptosis

(2022) Yaoqi Li et al.   APOPTOSIS

Tumor-derived extracellular vesicles shuttle c-Myc to promote gastric cancer growth and metastasis via the KCNQ1OT1/miR-556-3p/CLIC1 axis

(2022) Bopei Li et al.   Cell Death & Disease

Polydatin prevents lipotoxicity-induced dysfunction in pancreatic β-cells by inhibiting endoplasmic reticulum stress and excessive autophagy

(2022) Wenqi Jin et al.   PHYTOMEDICINE

Neuronal cell death mechanisms in Alzheimer’s disease: An insight

(2022) Parul Goel et al.   Frontiers in Molecular Neuroscience

SLC40A1 mediates ferroptosis and cognitive dysfunction in type 1 diabetes

(2021) Lijun Hao et al.   NEUROSCIENCE

Correction to: Diosmetin induces apoptosis in ovarian cancer cells by activating reactive oxygen species and inhibiting the Nrf2 pathway

(2021) Feijie Zhao et al.   MEDICAL ONCOLOGY

Liraglutide Alleviates Cognitive Deficit in db/db Mice: Involvement in Oxidative Stress, Iron Overload, and Ferroptosis

(2021) Ji-Ren An et al.   NEUROCHEMICAL RESEARCH

Mechanism of Ferroptosis and Its Role in Type 2 Diabetes Mellitus

(2021) Wenxin Sha et al.   Journal of Diabetes Research

Activation of Nrf2/HO-1 signaling: An important molecular mechanism of herbal medicine in the treatment of atherosclerosis via the protection of vascular endothelial cells from oxidative stress

(2021) Qing Zhang et al.   Journal of Advanced Research

The impact of diabetes on cognitive impairment and its progression to dementia

(2021) Abigail Dove et al.   Alzheimers & Dementia

Application of glutathione depletion in cancer therapy: Enhanced ROS-based therapy, ferroptosis, and chemotherapy

(2021) Boyi Niu et al.   BIOMATERIALS

Ferroptosis and NRF2: an emerging battlefield in the neurodegeneration of Alzheimer's disease

(2021) Darius J.R. Lane et al.   Essays in Biochemistry

Diet Effects on Cerebrospinal Fluid Amino Acids Levels in Adults with Normal Cognition and Mild Cognitive Impairment

(2021) Kate J. Russin et al.   JOURNAL OF ALZHEIMERS DISEASE

The role of traditional Chinese medicine in the treatment of cognitive dysfunction in type 2 diabetes

(2021) Jinni Meng et al.   JOURNAL OF ETHNOPHARMACOLOGY

Microglia and macrophage exhibit attenuated inflammatory response and ferroptosis resistance after RSL3 stimulation via increasing Nrf2 expression

(2021) Yu Cui et al.   Journal of Neuroinflammation

Plantago asiatica L. seeds extract protects against cardiomyocyte injury in isoproterenol- induced cardiac hypertrophy by inhibiting excessive autophagy and apoptosis in mice

(2021) Wenjing Fan et al.   PHYTOMEDICINE

Ferroptosis: past, present and future

(2020) Jie Li et al.   Cell Death & Disease

SIRT3 deficiency is resistant to autophagy‐dependent ferroptosis by inhibiting the AMPK/mTOR pathway and promoting GPX4 levels

(2020) Dandan Han et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Nrf2 and Ferroptosis: A New Research Direction for Neurodegenerative Diseases

(2020) Xiaohua Song et al.   Frontiers in Neuroscience

Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells

(2020) Yanying Zhao et al.   JOURNAL OF DAIRY SCIENCE

Novel target for treating Alzheimer’s Diseases: Crosstalk between the Nrf2 pathway and autophagy

(2020) Weiwei Zhang et al.   AGEING RESEARCH REVIEWS

NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis

(2019) Matthew Dodson et al.   Redox Biology

Ferroptosis is a type of autophagy-dependent cell death

(2019) Borong Zhou et al.   SEMINARS IN CANCER BIOLOGY

NLRP3 inflammasome inhibition with MCC950 improves diabetes-mediated cognitive impairment and vasoneuronal remodeling after ischemia

(2019) Rebecca Ward et al.   PHARMACOLOGICAL RESEARCH

Anti-neuroinflammatory and antioxidant phenylpropanoids from Chinese olive

(2019) Shujuan Zhang et al.   FOOD CHEMISTRY

Nrf2 drives oxidative stress-induced autophagy in nucleus pulposus cells via a Keap1/Nrf2/p62 feedback loop to protect intervertebral disc from degeneration

(2019) Zehan Tang et al.   Cell Death & Disease

Neurocognitive impairment in type 2 diabetes mellitus

(2019) Marianna Karvani et al.   Hormones-International Journal of Endocrinology and Metabolism

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

(2019) Lian-Jiu Su et al.   Oxidative Medicine and Cellular Longevity

ROS-mediated autophagy increases intracellular iron levels and ferroptosis by ferritin and transferrin receptor regulation

(2019) Eunhee Park et al.   Cell Death & Disease

Myocarditis: somethings old and something new

(2019) Dana Razzano et al.   CARDIOVASCULAR PATHOLOGY

High glucose augments ROS generation regulates mitochondrial dysfunction and apoptosis via stress signalling cascades in keratinocytes

(2019) Huma Rizwan et al.   LIFE SCIENCES

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

(2018) Lorenzo Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Cognitive decline and dementia in diabetes mellitus: mechanisms and clinical implications

(2018) Geert Jan Biessels et al.   Nature Reviews Endocrinology

Targeting Nrf2 to Suppress Ferroptosis and Mitochondrial Dysfunction in Neurodegeneration

(2018) Moataz Abdalkader et al.   Frontiers in Neuroscience

High glucose-induced oxidative stress impairs proliferation and migration of human gingival fibroblasts

(2018) Prima Buranasin et al.   PLoS One

Induction of ferroptosis and mitochondrial dysfunction by oxidative stress in PC12 cells

(2018) Chuanhong Wu et al.   Scientific Reports

Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer

(2018) Daiha Shin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Survival or death: a dual role for autophagy in stress-induced pericyte loss in diabetic retinopathy

(2016) Dongxu Fu et al.   DIABETOLOGIA

Synergy in traditional Chinese medicine

(2016) Tianhan Xue   LANCET ONCOLOGY

Activation and cleavage of SASH1 by caspase-3 mediates an apoptotic response

(2016) Joshua T Burgess et al.   Cell Death & Disease

Tumor suppression by autophagy through the management of metabolic stress

(2014) Shengkan V. Jin et al.   Autophagy

5-HMF prevents against oxidative injury via APE/Ref-1

(2014) J.-H. Zhang et al.   FREE RADICAL RESEARCH

5-Hydroxymethylfurfural, an antioxidant agent from Alpinia oxyphylla Miq. improves cognitive impairment in Aβ1–42 mouse model of Alzheimer's disease

(2014) Aijing Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Diabetes and the Brain: Oxidative Stress, Inflammation, and Autophagy

(2014) María Muriach et al.   Oxidative Medicine and Cellular Longevity

Diabetes Mellitus and Inflammation

(2013) Eric Lontchi-Yimagou et al.   Current Diabetes Reports

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Effects of cysteamine on MPTP-induced dopaminergic neurodegeneration in mice

(2010) Linjuan Sun et al.   BRAIN RESEARCH

Lectin purified from Musca domestica pupa up-regulates NO and iNOS production via TLR4/NF-κB signaling pathway in macrophages

(2010) Xiaohong Cao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

p62/SQSTM1Is a Target Gene for Transcription Factor NRF2 and Creates a Positive Feedback Loop by Inducing Antioxidant Response Element-driven Gene Transcription

(2010) Ashish Jain et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Suppressive Effects of Hydroxytyrosol on Oxidative Stress and Nuclear Factor-κB Activation in THP-1 Cells

(2009) Xiaomei Zhang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN