Trigonochinene E promotes lysosomal biogenesis and enhances autophagy via TFEB/TFE3 in human degenerative NP cells against oxidative stress

Kazinol C from Broussonetia kazinoki stimulates autophagy via endoplasmic reticulum stress-mediated signaling

(2022) Yunkyeong Lee et al.   Animal Cells and Systems

Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques

(2022) Ju-Hyun Lee et al.   NATURE NEUROSCIENCE

Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegeneration

(2022) Ryan T. Vest et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lysosome biogenesis: Regulation and functions

(2021) Chonglin Yang et al.   JOURNAL OF CELL BIOLOGY

Full-coverage regulations of autophagy by ROS: from induction to maturation

(2021) Jing Zhou et al.   Autophagy

Endoplasmic reticulum stress promotes HBV production by enhancing use of the autophagosome/multivesicular body axis

(2021) Xueyu Wang et al.   HEPATOLOGY

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System

(2020) Jingyue Jia et al.   MOLECULAR CELL

The unfolded protein response regulates hepatic autophagy by sXBP1-mediated activation of TFEB

(2020) Zeyuan Zhang et al.   Autophagy

Hierarchical activation of compartmentalized pools of AMPK depends on severity of nutrient or energy stress

(2019) Yue Zong et al.   CELL RESEARCH

The kinase PERK and the transcription factor ATF4 play distinct and essential roles in autophagy resulting from tunicamycin-induced ER stress

(2019) Morten Luhr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 contributes to lysosomal-mediated cell death in a novel derivative of riccardin D-treated breast cancer cells in association with TFEB

(2018) Lin Li et al.   BIOCHEMICAL PHARMACOLOGY

STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses

(2018) Lidia Avalle et al.   CELL DEATH AND DIFFERENTIATION

TFEB and TFE3: Linking Lysosomes to Cellular Adaptation to Stress

(2016) Nina Raben et al.   Annual Review of Cell and Developmental Biology

TFEB and TFE3 are novel components of the integrated stress response

(2016) J. A. Martina et al.   EMBO JOURNAL

Protein kinase C controls lysosome biogenesis independently of mTORC1

(2016) Yang Li et al.   NATURE CELL BIOLOGY

The role of STAT3 in autophagy

(2015) Liangkun You et al.   Autophagy

Organelle autoregulation--stress responses in the ER, Golgi, mitochondria and lysosome

(2015) K. Sasaki et al.   JOURNAL OF BIOCHEMISTRY

Role for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses

(2015) Yang Liu et al.   JOURNAL OF HEPATOLOGY

Autophagy in the Degenerating Human Intervertebral Disc

(2015) Helen E. Gruber et al.   SPINE

Trigoflavidols A–C, Degraded Diterpenoids with Antimicrobial Activity, from Trigonostemon flavidus

(2012) Gui-Hua Tang et al.   JOURNAL OF NATURAL PRODUCTS

Cytoplasmic STAT3 Represses Autophagy by Inhibiting PKR Activity

(2012) Shensi Shen et al.   MOLECULAR CELL

Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways

(2011) Michela Palmieri et al.   HUMAN MOLECULAR GENETICS

Antimicrobial Diterpenes fromTrigonostemon chinensis

(2008) Sheng Yin et al.   JOURNAL OF NATURAL PRODUCTS