STAT3 localizes to the ER, acting as a gatekeeper for ER-mitochondrion Ca2+ fluxes and apoptotic responses

Mitochondrial and endoplasmic reticulum calcium homeostasis and cell death

(2018) Saverio Marchi et al.   CELL CALCIUM

JAK/STAT pathway directed therapy of T-cell leukemia/lymphoma: Inspired by functional and structural genomics

(2017) Thomas A. Waldmann   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Use of luciferase probes to measure ATP in living cells and animals

(2017) Giampaolo Morciano et al.   Nature Protocols

The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis

(2017) M Gueguinou et al.   ONCOGENE

Downregulation of type 3 inositol (1,4,5)-trisphosphate receptor decreases breast cancer cell migration through an oscillatory Ca2+ signal

(2017) Abdallah Mound et al.   Oncotarget

Calcium-regulatory proteins as modulators of chemotherapy in human neuroblastoma

(2017) Ana-Maria Florea et al.   Oncotarget

ER functions of oncogenes and tumor suppressors: Modulators of intracellular Ca 2+ signaling

(2016) Mart Bittremieux et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The mitochondrial calcium uniporter regulates breast cancer progression via HIF‐1α

(2016) Anna Tosatto et al.   EMBO Molecular Medicine

Mitochondrial Stat3, the Need for Design Thinking

(2016) Rui Yang et al.   International Journal of Biological Sciences

A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

(2016) Marco Demaria et al.   Aging-US

Mitochondria-Associated Membranes: Composition, Molecular Mechanisms, and Physiopathological Implications

(2015) Carlotta Giorgi et al.   ANTIOXIDANTS & REDOX SIGNALING

Inositol 1,4,5-trisphosphate receptors in the endoplasmic reticulum: A single-channel point of view

(2015) Don-On Daniel Mak et al.   CELL CALCIUM

Molecular identity of the mitochondrial permeability transition pore and its role in ischemia-reperfusion injury

(2015) Giampaolo Morciano et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The endoplasmic reticulum mitochondrial calcium cross talk is downregulated in malignant pleural mesothelioma cells and plays a critical role in apoptosis inhibition

(2015) Simone Patergnani et al.   Oncotarget

Inositol 1,4,5-trisphosphate receptor-isoform diversity in cell death and survival

(2014) Hristina Ivanova et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Bioinformatic analysis reveals a pattern of STAT3-associated gene expression specific to basal-like breast cancers in human tumors

(2014) R. W. Tell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of PTEN at the ER and MAMs and its regulation of Ca2+ signaling and apoptosis in a protein phosphatase-dependent manner

(2013) A Bononi et al.   CELL DEATH AND DIFFERENTIATION

Subcellular calcium measurements in mammalian cells using jellyfish photoprotein aequorin-based probes

(2013) Massimo Bonora et al.   Nature Protocols

STAT3 can serve as a hit in the process of malignant transformation of primary cells

(2012) M Demaria et al.   CELL DEATH AND DIFFERENTIATION

Comprehensive molecular portraits of human breast tumours

(2012) Daniel C. Koboldt et al.   NATURE

Somatic mutations activating STAT3 in human inflammatory hepatocellular adenomas

(2011) Camilla Pilati et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Caffeine-Mediated Inhibition of Calcium Release Channel Inositol 1,4,5-Trisphosphate Receptor Subtype 3 Blocks Glioblastoma Invasion and Extends Survival

(2010) S. S. Kang et al.   CANCER RESEARCH

Stoichiometry of STAT3 and Mitochondrial Proteins

(2010) Darci Phillips et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PML Regulates Apoptosis at Endoplasmic Reticulum by Modulating Calcium Release

(2010) C. Giorgi et al.   SCIENCE

The RhoU/Wrch1 Rho GTPase gene is a common transcriptional target of both the gp130/STAT3 and Wnt-1 pathways

(2009) Davide Schiavone et al.   BIOCHEMICAL JOURNAL

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

The BH4 domain of Bcl-2 inhibits ER calcium release and apoptosis by binding the regulatory and coupling domain of the IP3 receptor

(2009) Y.-P. Rong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial STAT3 Supports Ras-Dependent Oncogenic Transformation

(2009) D. J. Gough et al.   SCIENCE

Function of Mitochondrial Stat3 in Cellular Respiration

(2009) J. Wegrzyn et al.   SCIENCE