Development of cross-species translational paradigms for psychiatric research in the Research Domain Criteria era

Shared and distinct reward neural mechanisms among patients with schizophrenia, major depressive disorder, and bipolar disorder: an effort-based functional imaging study

(2022) Yan-yu Wang et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

EEG reveals that dextroamphetamine improves cognitive control through multiple processes in healthy participants

(2022) Savita G. Bhakta et al.   NEUROPSYCHOPHARMACOLOGY

Amphetamine alters an EEG marker of reward processing in humans and mice

(2022) James F. Cavanagh et al.   PSYCHOPHARMACOLOGY

Depression reduces neural correlates of reward salience with increasing effort over the course of the progressive ratio task

(2022) Julia Klawohn et al.   JOURNAL OF AFFECTIVE DISORDERS

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

(2022) Vassily Trubetskoy et al.   NATURE

Reinforcement learning deficits exhibited by postnatal PCP-treated rats enable deep neural network classification

(2022) Michael M. Tranter et al.   NEUROPSYCHOPHARMACOLOGY

Effect of lysergic acid diethylamide (LSD) on reinforcement learning in humans

(2022) Jonathan W. Kanen et al.   PSYCHOLOGICAL MEDICINE

Pre-deployment threat learning predicts increased risk for post-deployment insomnia: Evidence from the Marine Resiliency Study

(2022) Christopher Hunt et al.   BEHAVIOUR RESEARCH AND THERAPY

Translational cognitive systems: focus on attention

(2022) Benjamin Z. Roberts et al.   Emerging Topics in Life Sciences

Are methamphetamine users compulsive? Faulty reinforcement learning, not inflexibility, underlies decision making in people with methamphetamine use disorder

(2021) Alex H. Robinson et al.   ADDICTION BIOLOGY

Medial orbitofrontal cortex dopamine D1/D2 receptors differentially modulate distinct forms of probabilistic decision-making

(2021) Nicole L. Jenni et al.   NEUROPSYCHOPHARMACOLOGY

Convergent observations of MK-801-induced impairment in rat 5C-CPT performance across laboratories: reversal with a D1 but not nicotinic agonist

(2021) Andrew J. Grottick et al.   PSYCHOPHARMACOLOGY

Distinct outcome processing in deterministic and probabilistic reversal learning

(2021) Selim Habiby Alaoui et al.   CORTEX

Neural networks during delay discounting as trans-disease marker: a meta-analytical review

(2021) Zhiyi. Chen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Concordant neurophysiological signatures of cognitive control in humans and rats

(2021) Mykel A. Robble et al.   NEUROPSYCHOPHARMACOLOGY

Model-Based Planning Deficits in Compulsivity Are Linked to Faulty Neural Representations of Task Structure

(2021) Tricia X. F. Seow et al.   JOURNAL OF NEUROSCIENCE

Electrophysiological biomarkers of behavioral dimensions from cross-species paradigms

(2021) James F. Cavanagh et al.   Translational Psychiatry

Manipulating feedback on schizophrenia: Evidence from a Posner task

(2021) Elena Serrano-Lozano et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Over-representation of potential SP4 target genes within schizophrenia-risk genes

(2021) Xianjin Zhou   MOLECULAR PSYCHIATRY

Decision-making in suicidal behavior: A systematic review and meta-analysis

(2021) Aina Sastre-Buades et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Investigation of reward learning and feedback sensitivity in non-clinical participants with a history of early life stress

(2021) Matthew Paul Wilkinson et al.   PLoS One

Probabilistic reversal learning under acute tryptophan depletion in healthy humans: a conventional analysis

(2020) Jonathan W Kanen et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Amphetamine improves rat 5-choice continuous performance test (5C-CPT) irrespective of concurrent low-dose haloperidol treatment

(2020) Jared W. Young et al.   PSYCHOPHARMACOLOGY

Dose-response effects of d-amphetamine on effort-based decision-making and reinforcement learning

(2020) Heather E. Soder et al.   NEUROPSYCHOPHARMACOLOGY

Assessing attention orienting in mice: a novel touchscreen adaptation of the Posner-style cueing task

(2020) S. Li et al.   NEUROPSYCHOPHARMACOLOGY

The effects of FAAH inhibition on the neural basis of anxiety-related processing in healthy male subjects: a randomized clinical trial

(2020) Martin P. Paulus et al.   NEUROPSYCHOPHARMACOLOGY

Convergent neural substrates of inattention in bipolar disorder patients and dopamine transporter‐deficient mice using the 5‐choice CPT

(2019) Jared W. Young et al.   BIPOLAR DISORDERS

Orbitofrontal Circuits Control Multiple Reinforcement-Learning Processes

(2019) Stephanie M. Groman et al.   NEURON

Error-related brain activity in adolescents with obsessive-compulsive disorder and major depressive disorder

(2018) Gregory L. Hanna et al.   DEPRESSION AND ANXIETY

Independent effects of age and levodopa on reversal learning in healthy volunteers

(2018) Andrew Vo et al.   NEUROBIOLOGY OF AGING

Amphetamine improves mouse and human attention in the 5-choice continuous performance test

(2018) David A. MacQueen et al.   NEUROPHARMACOLOGY

Cognitive Flexibility Deficits Following 6-OHDA Lesions of the Rat Dorsomedial Striatum

(2018) Gena M. Grospe et al.   NEUROSCIENCE

Assessment of intradimensional/extradimensional attentional set-shifting in rats

(2018) David S. Tait et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Individual differences in the energizing effects of caffeine on effort-based decision-making tests in rats

(2018) Noemí SanMiguel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Reverse translated and gold standard continuous performance tests predict global cognitive performance in schizophrenia

(2018) Andrew W. Bismark et al.   Translational Psychiatry

Nicotine improves probabilistic reward learning in wildtype but not alpha7 nAChR null mutants, yet alpha7 nAChR agonists do not improve probabilistic learning

(2018) Morgane Milienne-Petiot et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Effects of aging on executive functioning and mesocorticolimbic dopamine markers in male Fischer 344 × brown Norway rats

(2018) Ryan J. Tomm et al.   NEUROBIOLOGY OF AGING

Response inhibition and interference control: Effects of schizophrenia, genetic risk, and schizotypy

(2017) Ulrich Ettinger et al.   Journal of Neuropsychology

Amphetamine Modestly Improves Conners’ Continuous Performance Test Performance in Healthy Adults

(2017) David A. MacQueen et al.   JOURNAL OF THE INTERNATIONAL NEUROPSYCHOLOGICAL SOCIETY

Chronic Exposure to Methamphetamine Disrupts Reinforcement-Based Decision Making in Rats

(2017) Stephanie M Groman et al.   NEUROPSYCHOPHARMACOLOGY

Research Domain Criteria versus DSM V: How does this debate affect attempts to model corticostriatal dysfunction in animals?

(2017) Jared W. Young et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Nicotine withdrawal-induced inattention is absent in alpha7 nAChR knockout mice

(2017) K. K . Higa et al.   PSYCHOPHARMACOLOGY

Relationship between effortful motivation and neurocognition in schizophrenia

(2017) Andrew W. Bismark et al.   SCHIZOPHRENIA RESEARCH

Varenicline, the clinically effective smoking cessation agent, restores probabilistic response reversal performance during withdrawal from nicotine

(2016) Anne Jackson et al.   ADDICTION BIOLOGY

Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers

(2016) Brett A. Clementz et al.   AMERICAN JOURNAL OF PSYCHIATRY

Dopamine D1 receptor activation improves PCP-induced performance disruption in the 5C-CPT by reducing inappropriate responding

(2016) S.A. Barnes et al.   BEHAVIOURAL BRAIN RESEARCH

Diminished effort on a progressive ratio task in both unipolar and bipolar depression

(2016) Rachel Hershenberg et al.   JOURNAL OF AFFECTIVE DISORDERS

Sensorimotor gating of the startle reflex: what we said 25 years ago, what has happened since then, and what comes next

(2016) Neal R Swerdlow et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Diminished caudate and superior temporal gyrus responses to effort-based decision making in patients with first-episode major depressive disorder

(2016) Xin-hua Yang et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Probabilistic Reversal Learning in Schizophrenia: Stability of Deficits and Potential Causal Mechanisms

(2016) Lena Felice Reddy et al.   SCHIZOPHRENIA BULLETIN

Avolition in schizophrenia is associated with reduced willingness to expend effort for reward on a Progressive Ratio task

(2016) Gregory P. Strauss et al.   SCHIZOPHRENIA RESEARCH

Inefficient effort allocation and negative symptoms in individuals with schizophrenia

(2016) Julie M. McCarthy et al.   SCHIZOPHRENIA RESEARCH

The GABAB receptor positive modulator BHF177 attenuated anxiety, but not conditioned fear, in rats

(2015) Xia Li et al.   NEUROPHARMACOLOGY

GlyT-1 Inhibition Attenuates Attentional But Not Learning or Motivational Deficits of the Sp4 Hypomorphic Mouse Model Relevant to Psychiatric Disorders

(2015) Jared W Young et al.   NEUROPSYCHOPHARMACOLOGY

Negative affective states and cognitive impairments in nicotine dependence

(2015) F. Scott Hall et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Introduction to the special issue from the 2014 meeting of the International Behavioral Neuroscience Society

(2015) Jared W. Young et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Feasibility of use of probabilistic reversal learning and serial reaction time tasks in clinical trials of Parkinson's disease

(2015) Melissa T. Buelow et al.   PARKINSONISM & RELATED DISORDERS

Intact error monitoring in combat Veterans with post-traumatic stress disorder

(2015) Diane Swick et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

A computational analysis of flanker interference in depression

(2015) D. G. Dillon et al.   PSYCHOLOGICAL MEDICINE

Amphetamine increases activity but not exploration in humans and mice

(2015) Arpi Minassian et al.   PSYCHOPHARMACOLOGY

The continuous performance test (rCPT) for mice: a novel operant touchscreen test of attentional function

(2015) Chi Hun Kim et al.   PSYCHOPHARMACOLOGY

Impaired Activation in Cognitive Control Regions Predicts Reversal Learning in Schizophrenia

(2015) Adam J. Culbreth et al.   SCHIZOPHRENIA BULLETIN

Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia

(2015) Jared W. Young et al.   SCHIZOPHRENIA BULLETIN

Effort-Based Decision-Making Paradigms for Clinical Trials in Schizophrenia: Part 2—External Validity and Correlates

(2015) William P. Horan et al.   SCHIZOPHRENIA BULLETIN

Motivation and value influences in the relative balance of goal-directed and habitual behaviours in obsessive-compulsive disorder

(2015) V Voon et al.   Translational Psychiatry

Reduced Dopamine Transporter Functioning Induces High-Reward Risk-Preference Consistent with Bipolar Disorder

(2014) Jordy van Enkhuizen et al.   NEUROPSYCHOPHARMACOLOGY

Intensity and pleasantness of sucrose taste in patients with winter depression

(2014) Lukasz Swiecicki et al.   NUTRITIONAL NEUROSCIENCE

Association Between Nicotine Withdrawal and Reward Responsiveness in Humans and Rats

(2014) Michele L. Pergadia et al.   JAMA Psychiatry

Sleep deprivation impairs performance in the 5-choice continuous performance test: Similarities between humans and mice

(2013) Jordy van Enkhuizen et al.   BEHAVIOURAL BRAIN RESEARCH

The relationship between depressive symptoms and error monitoring during response switching

(2013) Hans S. Schroder et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Reduced expression of SP1 and SP4 transcription factors in peripheral blood mononuclear cells in first-episode psychosis

(2013) Montserrat Fusté et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Bridging the bench to bedside gap: validation of a reverse-translated rodent continuous performance test using functional magnetic resonance imaging

(2013) Benjamin S. McKenna et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Increased distractor vulnerability but preserved vigilance in patients with schizophrenia: Evidence from a translational Sustained Attention Task

(2013) Elise Demeter et al.   SCHIZOPHRENIA RESEARCH

Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice

(2013) J W Young et al.   Translational Psychiatry

Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research

(2013) A Der-Avakian et al.   Translational Psychiatry

Increased Medial Orbitofrontal and Amygdala Activation: Evidence for a Systems-Level Endophenotype of Bipolar I Disorder

(2012) Julia Linke et al.   AMERICAN JOURNAL OF PSYCHIATRY

Chronic valproate attenuates some, but not all, facets of mania-like behaviour in mice

(2012) Jordy van Enkhuizen et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Adults with autism spectrum disorders exhibit decreased sensitivity to reward parameters when making effort-based decisions

(2012) Cara R Damiano et al.   Journal of Neurodevelopmental Disorders

Unaffected control of distractor interference in schizophrenia: A meta-analysis of incompatibility slowing in flanker tasks

(2012) René Westerhausen et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Medial prefrontal cortex lesions in mice do not impair effort-based decision making

(2012) Christine Solinsky et al.   NEUROPHARMACOLOGY

Consideration of species differences in developing novel molecules as cognition enhancers

(2012) Jared W. Young et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Caffeine increases psychomotor performance on the effort expenditure for rewards task

(2012) Margaret C. Wardle et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia

(2012) Christopher G. AhnAllen et al.   PSYCHIATRY RESEARCH

The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium

(2011) Raquel Pinacho et al.   BIPOLAR DISORDERS

Cigarette smoking status in pathological gamblers: Association with impulsivity and cognitive flexibility

(2011) Marc E. Mooney et al.   DRUG AND ALCOHOL DEPENDENCE

Amping Up Effort: Effects of d-Amphetamine on Human Effort-Based Decision-Making

(2011) M. C. Wardle et al.   JOURNAL OF NEUROSCIENCE

D1 receptor activation improves vigilance in rats as measured by the 5-choice continuous performance test

(2011) Samuel A. Barnes et al.   PSYCHOPHARMACOLOGY

Sweet preferences and analgesia during childhood: effects of family history of alcoholism and depression

(2010) Julie A. Mennella et al.   ADDICTION

Confirmed rare copy number variants implicate novel genes in schizophrenia

(2010) Gloria W.C. Tam et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The mouse attentional-set-shifting task: A method for assaying successful cognitive aging?

(2010) Jared W. Young et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Reduced NMDAR1 expression in the Sp4 hypomorphic mouse may contribute to endophenotypes of human psychiatric disorders

(2010) Xianjin Zhou et al.   HUMAN MOLECULAR GENETICS

Genome-wide association study of recurrent early-onset major depressive disorder

(2010) J Shi et al.   MOLECULAR PSYCHIATRY

Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats

(2010) Andrea Bari et al.   NEUROPSYCHOPHARMACOLOGY

A Reverse-Translational Study of Dysfunctional Exploration in Psychiatric Disorders

(2009) William Perry et al.   ARCHIVES OF GENERAL PSYCHIATRY

The 5-Choice Continuous Performance Test: Evidence for a Translational Test of Vigilance for Mice

(2009) Jared W. Young et al.   PLoS One

Transcription Factor SP4 Is a Susceptibility Gene for Bipolar Disorder

(2009) Xianjin Zhou et al.   PLoS One

Worth the ‘EEfRT’? The Effort Expenditure for Rewards Task as an Objective Measure of Motivation and Anhedonia

(2009) Michael T. Treadway et al.   PLoS One

Test–retest reliability of event-related functional MRI in a probabilistic reversal learning task

(2009) Tobias Freyer et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Euthymic Patients with Bipolar Disorder Show Decreased Reward Learning in a Probabilistic Reward Task

(2008) Diego A. Pizzagalli et al.   BIOLOGICAL PSYCHIATRY

Reduced hedonic capacity in major depressive disorder: Evidence from a probabilistic reward task

(2008) Diego A. Pizzagalli et al.   JOURNAL OF PSYCHIATRIC RESEARCH