Translational Rodent Paradigms to Investigate Neuromechanisms Underlying Behaviors Relevant to Amotivation and Altered Reward Processing in Schizophrenia

Reward processing dysfunction in major depression, bipolar disorder and schizophrenia

(2015) Alexis E. Whitton et al.   CURRENT OPINION IN PSYCHIATRY

The NIMH Research Domain Criteria (RDoC) Project: Precision Medicine for Psychiatry

(2014) Thomas R. Insel   AMERICAN JOURNAL OF PSYCHIATRY

Preferential Involvement by Nucleus Accumbens Shell in Mediating Probabilistic Learning and Reversal Shifts

(2014) G. L. Dalton et al.   JOURNAL OF NEUROSCIENCE

Working Memory Contributions to Reinforcement Learning Impairments in Schizophrenia

(2014) Anne G.E. Collins et al.   JOURNAL OF NEUROSCIENCE

Developing treatments for cognitive deficits in schizophrenia: The challenge of translation

(2014) JW Young et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Reduced Dopamine Transporter Functioning Induces High-Reward Risk-Preference Consistent with Bipolar Disorder

(2014) Jordy van Enkhuizen et al.   NEUROPSYCHOPHARMACOLOGY

Dissociable Contributions of Anterior Cingulate Cortex and Basolateral Amygdala on a Rodent Cost/Benefit Decision-Making Task of Cognitive Effort

(2014) Jay G Hosking et al.   NEUROPSYCHOPHARMACOLOGY

A Randomized, Placebo-Controlled Study Investigating the Nicotinic α7 Agonist, RG3487, for Cognitive Deficits in Schizophrenia

(2014) Daniel Umbricht et al.   NEUROPSYCHOPHARMACOLOGY

Dopamine Antagonism Decreases Willingness to Expend Physical, But Not Cognitive, Effort: A Comparison of Two Rodent Cost/Benefit Decision-Making Tasks

(2014) Jay G Hosking et al.   NEUROPSYCHOPHARMACOLOGY

Amotivation in Schizophrenia: Integrated Assessment With Behavioral, Clinical, and Imaging Measures

(2014) Daniel H. Wolf et al.   SCHIZOPHRENIA BULLETIN

Neuropsychology of reward learning and negative symptoms in schizophrenia

(2014) Paul G. Nestor et al.   SCHIZOPHRENIA RESEARCH

The RDoC framework: facilitating transition from ICD/DSM to dimensional approaches that integrate neuroscience and psychopathology

(2014) Bruce N. Cuthbert   World Psychiatry

Association Between Nicotine Withdrawal and Reward Responsiveness in Humans and Rats

(2014) Michele L. Pergadia et al.   JAMA Psychiatry

Evaluating the role of the alpha-7 nicotinic acetylcholine receptor in the pathophysiology and treatment of schizophrenia

(2013) Jared W. Young et al.   BIOCHEMICAL PHARMACOLOGY

Isolation rearing effects on probabilistic learning and cognitive flexibility in rats

(2013) Nurith Amitai et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Anhedonia, avolition, and anticipatory deficits: Assessments in animals with relevance to the negative symptoms of schizophrenia

(2013) Samuel A. Barnes et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

What's better for me? Fundamental role for lateral habenula in promoting subjective decision biases

(2013) Colin M Stopper et al.   NATURE NEUROSCIENCE

A Randomized Exploratory Trial of an Alpha-7 Nicotinic Receptor Agonist (TC-5619) for Cognitive Enhancement in Schizophrenia

(2013) Jeffrey A Lieberman et al.   NEUROPSYCHOPHARMACOLOGY

Measuring reinforcement learning and motivation constructs in experimental animals: Relevance to the negative symptoms of schizophrenia

(2013) Athina Markou et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Towards improved animal models for evaluating social cognition and its disruption in schizophrenia: The CNTRICS initiative

(2013) Mark J. Millan et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Reverse translation of the rodent 5C-CPT reveals that the impaired attention of people with schizophrenia is similar to scopolamine-induced deficits in mice

(2013) J W Young et al.   Translational Psychiatry

Assessment of reward responsiveness in the response bias probabilistic reward task in rats: implications for cross-species translational research

(2013) A Der-Avakian et al.   Translational Psychiatry

From Perception to Functional Outcome in Schizophrenia

(2012) Michael F. Green et al.   ARCHIVES OF GENERAL PSYCHIATRY

Male and female Wistar rats differ in decision-making performance in a rodent version of the Iowa Gambling Task

(2012) Ruud van den Bos et al.   BEHAVIOURAL BRAIN RESEARCH

Reduced Reward Learning Predicts Outcome in Major Depressive Disorder

(2012) Elske Vrieze et al.   BIOLOGICAL PSYCHIATRY

The Behavioral Pharmacology of Effort-related Choice Behavior: Dopamine, Adenosine and Beyond

(2012) John D Salamone et al.   JOURNAL OF THE EXPERIMENTAL ANALYSIS OF BEHAVIOR

Sensitivity to Cognitive Effort Mediates Psychostimulant Effects on a Novel Rodent Cost/Benefit Decision-Making Task

(2012) Paul J Cocker et al.   NEUROPSYCHOPHARMACOLOGY

Consideration of species differences in developing novel molecules as cognition enhancers

(2012) Jared W. Young et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Assessment of Behaviors Modeling Aspects of Schizophrenia in Csmd1 Mutant Mice

(2012) Margaret G. Distler et al.   PLoS One

The relationship between reward-based learning and nicotine dependence in smokers with schizophrenia

(2012) Christopher G. AhnAllen et al.   PSYCHIATRY RESEARCH

Differential effects of dopamine transporter inhibitors in the rodent Iowa gambling task

(2012) Jordy van Enkhuizen et al.   PSYCHOPHARMACOLOGY

Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia II: Developing Imaging Biomarkers to Enhance Treatment Development for Schizophrenia and Related Disorders

(2011) Cameron S. Carter et al.   BIOLOGICAL PSYCHIATRY

Contributions of the nucleus accumbens and its subregions to different aspects of risk-based decision making

(2011) Colin M. Stopper et al.   COGNITIVE AFFECTIVE & BEHAVIORAL NEUROSCIENCE

Delayed procedural learning in α7-nicotinic acetylcholine receptor knockout mice

(2011) J. W. Young et al.   GENES BRAIN AND BEHAVIOR

Dissociable Contributions by Prefrontal D1 and D2 Receptors to Risk-Based Decision Making

(2011) J. R. St. Onge et al.   JOURNAL OF NEUROSCIENCE

Do GluA1 knockout mice exhibit behavioral abnormalities relevant to the negative or cognitive symptoms of schizophrenia and schizoaffective disorder?

(2011) Chris Barkus et al.   NEUROPHARMACOLOGY

Dopamine Receptor Blockade Attenuates the General Incentive Motivational Effects of Noncontingently Delivered Rewards and Reward-Paired Cues Without Affecting Their Ability to Bias Action Selection

(2011) Sean B Ostlund et al.   NEUROPSYCHOPHARMACOLOGY

D2 receptor overexpression in the striatum leads to a deficit in inhibitory transmission and dopamine sensitivity in mouse prefrontal cortex

(2011) Y.-C. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Food and Drug Administration Commentary on Methodological Issues in Negative Symptom Trials

(2011) T. Laughren et al.   SCHIZOPHRENIA BULLETIN

CNTRICS Final Biomarker Selection: Control of Attention

(2011) S. J. Luck et al.   SCHIZOPHRENIA BULLETIN

Methodological Issues in Negative Symptom Trials

(2011) S. R. Marder et al.   SCHIZOPHRENIA BULLETIN

CNTRICS Imaging Biomarkers Selection: Working Memory

(2011) D. M. Barch et al.   SCHIZOPHRENIA BULLETIN

Inter-Individual Decision-Making Differences in the Effects of Cingulate, Orbitofrontal, and Prelimbic Cortex Lesions in a Rat Gambling Task

(2011) Marion Rivalan et al.   Frontiers in Behavioral Neuroscience

Reduced Capacity but Spared Precision and Maintenance of Working Memory Representations in Schizophrenia

(2010) James M. Gold et al.   ARCHIVES OF GENERAL PSYCHIATRY

Choosing to Make an Effort: The Role of Striatum in Signaling Physical Effort of a Chosen Action

(2010) I. T. Kurniawan et al.   JOURNAL OF NEUROPHYSIOLOGY

Altered probabilistic learning and response biases in schizophrenia: Behavioral evidence and neurocomputational modeling.

(2010) James A. Waltz et al.   NEUROPSYCHOLOGY

Serotonin Modulates Sensitivity to Reward and Negative Feedback in a Probabilistic Reversal Learning Task in Rats

(2010) Andrea Bari et al.   NEUROPSYCHOPHARMACOLOGY

Neonatal maternal separation exacerbates the reward-enhancing effect of acute amphetamine administration and the anhedonic effect of repeated social defeat in adult rats

(2010) A. Der-Avakian et al.   NEUROSCIENCE

MK-801 produces a deficit in sucrose preference that is reversed by clozapine, d-serine, and the metabotropic glutamate 5 receptor positive allosteric modulator CDPPB: Relevance to negative symptoms associated with schizophrenia?

(2010) Joshua D. Vardigan et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Pathways between early visual processing and functional outcome in schizophrenia

(2010) Y. Rassovsky et al.   PSYCHOLOGICAL MEDICINE

Toward New Approaches to Psychotic Disorders: The NIMH Research Domain Criteria Project

(2010) B. N. Cuthbert et al.   SCHIZOPHRENIA BULLETIN

Risk-Prone Individuals Prefer the Wrong Options on a Rat Version of the Iowa Gambling Task

(2009) Marion Rivalan et al.   BIOLOGICAL PSYCHIATRY

Prefrontal Cortical Contribution to Risk-Based Decision Making

(2009) J. R. St. Onge et al.   CEREBRAL CORTEX

Fundamental Contribution by the Basolateral Amygdala to Different Forms of Decision Making

(2009) S. Ghods-Sharifi et al.   JOURNAL OF NEUROSCIENCE

Decision-Making Impairments in the Context of Intact Reward Sensitivity in Schizophrenia

(2008) Erin A. Heerey et al.   BIOLOGICAL PSYCHIATRY

The role of the dorsal striatum and dorsal hippocampus in probabilistic and deterministic odor discrimination tasks

(2008) H. E. Atallah et al.   LEARNING & MEMORY

Assessment of Glutamate Transporter GLAST (EAAT1)-Deficient Mice for Phenotypes Relevant to the Negative and Executive/Cognitive Symptoms of Schizophrenia

(2008) Rose-Marie Karlsson et al.   NEUROPSYCHOPHARMACOLOGY

Drug discrimination and neurochemical studies in α7 null mutant mice: tests for the role of nicotinic α7 receptors in dopamine release

(2008) Davide Quarta et al.   PSYCHOPHARMACOLOGY

A Single Dose of Nicotine Enhances Reward Responsiveness in Nonsmokers: Implications for Development of Dependence

(2007) Ruth S. Barr et al.   BIOLOGICAL PSYCHIATRY