A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
A neurodevelopmental epigenetic programme mediated by SMARCD3–DAB1–Reelin signalling is hijacked to promote medulloblastoma metastasis
Authors
Keywords
-
Journal
NATURE CELL BIOLOGY
Volume 25, Issue 3, Pages 493-507
Publisher
Springer Science and Business Media LLC
Online
2023-02-28
DOI
10.1038/s41556-023-01093-0
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Preclinical efficacy of ribavirin in SHH and group 3 medulloblastoma
- (2021) Sakibul Huq et al. Journal of Neurosurgery-Pediatrics
- Transcription factor chromatin profiling genome-wide using uliCUT&RUN in single cells and individual blastocysts
- (2021) Benjamin J. Patty et al. Nature Protocols
- Spatial and cell type transcriptional landscape of human cerebellar development
- (2021) Kimberly A. Aldinger et al. NATURE NEUROSCIENCE
- Visualizing and interpreting cancer genomics data via the Xena platform
- (2020) Mary J. Goldman et al. NATURE BIOTECHNOLOGY
- Molecular Heterogeneity and Cellular Diversity: Implications for Precision Treatment in Medulloblastoma
- (2020) Han Zou et al. Cancers
- The chromatin remodeling enzyme Chd4 regulates genome architecture in the mouse brain
- (2020) Jared V. Goodman et al. Nature Communications
- Inhibition of enhancer of zest homologue 2 is a potential therapeutic target for high-MYC medulloblastoma
- (2019) Manabu Natsumeda et al. NEUROPATHOLOGY
- Emerging connections between cerebellar development, behaviour and complex brain disorders
- (2019) Aaron Sathyanesan et al. NATURE REVIEWS NEUROSCIENCE
- Leptomeningeal dissemination: a sinister pattern of medulloblastoma growth
- (2019) Daniel W. Fults et al. Journal of Neurosurgery-Pediatrics
- Batch-normalization of cerebellar and medulloblastoma gene expression datasets utilizing empirically defined negative control genes
- (2019) Holger Weishaupt et al. BIOINFORMATICS
- Childhood cerebellar tumours mirror conserved fetal transcriptional programs
- (2019) Maria C. Vladoiu et al. NATURE
- A phase 1 and randomized, placebo‐controlled phase 2 trial of bevacizumab plus dasatinib in patients with recurrent glioblastoma: Alliance/North Central Cancer Treatment Group N0872
- (2019) Evanthia Galanis et al. CANCER
- Resolving medulloblastoma cellular architecture by single-cell genomics
- (2019) Volker Hovestadt et al. NATURE
- EZH2 targeting reduces medulloblastoma growth through epigenetic reactivation of the BAI1/p53 tumor suppressor pathway
- (2019) Hanwen Zhang et al. ONCOGENE
- Phase 1 trial, pharmacokinetics, and pharmacodynamics of dasatinib combined with crizotinib in children with recurrent or progressive high-grade and diffuse intrinsic pontine glioma
- (2018) Alberto Broniscer et al. PEDIATRIC BLOOD & CANCER
- Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups
- (2018) Tenley C. Archer et al. CANCER CELL
- A Single-Cell Transcriptional Atlas of the Developing Murine Cerebellum
- (2018) Robert A. Carter et al. CURRENT BIOLOGY
- Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data
- (2018) Hannah A. Pliner et al. MOLECULAR CELL
- Granule neuron precursor cell proliferation is regulated by NFIX and intersectin 1 during postnatal cerebellar development
- (2018) James Fraser et al. Brain Structure & Function
- The Human Transcription Factors
- (2018) Samuel A. Lambert et al. CELL
- Neuronal Migration During Development of the Cerebellum
- (2018) Maryam Rahimi-Balaei et al. Frontiers in Cellular Neuroscience
- The whole-genome landscape of medulloblastoma subtypes
- (2017) Paul A. Northcott et al. NATURE
- OTX2 Activity at Distal Regulatory Elements Shapes the Chromatin Landscape of Group 3 Medulloblastoma
- (2017) Gaylor Boulay et al. Cancer Discovery
- Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma
- (2017) BaoHan T. Vo et al. Cell Reports
- An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites
- (2017) Peter J Skene et al. eLife
- Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function
- (2017) Xin Sun et al. Biology Open
- The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
- (2016) David N. Louis et al. ACTA NEUROPATHOLOGICA
- Epigenetic Activation of WNT5A Drives Glioblastoma Stem Cell Differentiation and Invasive Growth
- (2016) Baoli Hu et al. CELL
- DiSCoVERing Innovative Therapies for Rare Tumors: Combining Genetically Accurate Disease Models with In Silico Analysis to Identify Novel Therapeutic Targets
- (2016) A. R. Hanaford et al. CLINICAL CANCER RESEARCH
- In vitro models of medulloblastoma: Choosing the right tool for the job
- (2016) Delyan P. Ivanov et al. JOURNAL OF BIOTECHNOLOGY
- Active medulloblastoma enhancers reveal subgroup-specific cellular origins
- (2016) Charles Y. Lin et al. NATURE
- Integrative Analysis Reveals the Transcriptional Collaboration between EZH2 and E2F1 in the Regulation of Cancer-Related Gene Expression
- (2015) H. Xu et al. MOLECULAR CANCER RESEARCH
- EpiFactors: a comprehensive database of human epigenetic factors and complexes
- (2015) Yulia A. Medvedeva et al. Database-The Journal of Biological Databases and Curation
- Development of the cerebellum: simple steps to make a 'little brain'
- (2014) T. Butts et al. DEVELOPMENT
- NFIB-Mediated Repression of the Epigenetic Factor Ezh2 Regulates Cortical Development
- (2014) M. Piper et al. JOURNAL OF NEUROSCIENCE
- Recurrence patterns across medulloblastoma subgroups: an integrated clinical and molecular analysis
- (2013) Vijay Ramaswamy et al. LANCET ONCOLOGY
- SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling
- (2013) N. V. Jordan et al. MOLECULAR AND CELLULAR BIOLOGY
- Transposition of native chromatin for fast and sensitive epigenomic profiling of open chromatin, DNA-binding proteins and nucleosome position
- (2013) Jason D Buenrostro et al. NATURE METHODS
- EZH2-Regulated DAB2IP Is a Medulloblastoma Tumor Suppressor and a Positive Marker for Survival
- (2012) M. Smits et al. CLINICAL CANCER RESEARCH
- Targeting the enhancer of zeste homologue 2 in medulloblastoma
- (2012) Irina Alimova et al. INTERNATIONAL JOURNAL OF CANCER
- Phase 1 trial of dasatinib plus erlotinib in adults with recurrent malignant glioma
- (2012) David A. Reardon et al. JOURNAL OF NEURO-ONCOLOGY
- EZH2 Oncogenic Activity in Castration-Resistant Prostate Cancer Cells Is Polycomb-Independent
- (2012) K. Xu et al. SCIENCE
- Development of the cerebellum: from gene expression patterns to circuit maps
- (2012) Joshua J. White et al. Wiley Interdisciplinary Reviews-Developmental Biology
- Molecular subgroups of medulloblastoma: the current consensus
- (2011) Michael D. Taylor et al. ACTA NEUROPATHOLOGICA
- Pediatric Phase I Trial and Pharmacokinetic Study of Dasatinib: A Report From the Children's Oncology Group Phase I Consortium
- (2011) Richard Aplenc et al. JOURNAL OF CLINICAL ONCOLOGY
- Context-Specific Regulation of NF-κB Target Gene Expression by EZH2 in Breast Cancers
- (2011) Shuet Theng Lee et al. MOLECULAR CELL
- Most Random Gene Expression Signatures Are Significantly Associated with Breast Cancer Outcome
- (2011) David Venet et al. PLoS Computational Biology
- Retrospective study of dasatinib for recurrent glioblastoma after bevacizumab failure
- (2010) C. Lu-Emerson et al. JOURNAL OF NEURO-ONCOLOGY
- Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum
- (2010) Takaki Miyata et al. Neural Development
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started