Hypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques

Human pluripotent stem-cell-derived islets ameliorate diabetes in non-human primates

(2022) Yuanyuan Du et al.   NATURE MEDICINE

A Comprehensive Atlas of Immunological Differences Between Humans, Mice, and Non-Human Primates

(2022) Zachary B. Bjornson-Hooper et al.   Frontiers in Immunology

The SIRPα–CD47 immune checkpoint in NK cells

(2021) Tobias Deuse et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Generation of insulin-producing pancreatic β cells from multiple human stem cell lines

(2021) Nathaniel J. Hogrebe et al.   Nature Protocols

Targeting the cytoskeleton to direct pancreatic differentiation of human pluripotent stem cells

(2020) Nathaniel J. Hogrebe et al.   NATURE BIOTECHNOLOGY

Minimal PD-1 expression in mouse and human NK cells under diverse conditions

(2020) Sean J. Judge et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene-edited human stem cell–derived β cells from a patient with monogenic diabetes reverse preexisting diabetes in mice

(2020) Kristina G. Maxwell et al.   Science Translational Medicine

Pluripotent Stem Cell-Based Cell Therapy—Promise and Challenges

(2020) Shinya Yamanaka   Cell Stem Cell

Hypoimmunogenic derivatives of induced pluripotent stem cells evade immune rejection in fully immunocompetent allogeneic recipients

(2019) Tobias Deuse et al.   NATURE BIOTECHNOLOGY

Evidence for the important role of inflammation in xenotransplantation

(2019) Juan Li et al.   Journal of Inflammation-London

HLA-G peptide preferences change in transformed cells: impact on the binding motif

(2018) Alexander A. Celik et al.   IMMUNOGENETICS

Advanced maturation of human cardiac tissue grown from pluripotent stem cells

(2018) Kacey Ronaldson-Bouchard et al.   NATURE

Endogenous glucocorticoids control host resistance to viral infection through the tissue-specific regulation of PD-1 expression on NK cells

(2018) Linda Quatrini et al.   NATURE IMMUNOLOGY

Human Leukocyte Antigen Class I and II Knockout Human Induced Pluripotent Stem Cell–Derived Cells: Universal Donor for Cell Therapy

(2018) Saidulu Mattapally et al.   Journal of the American Heart Association

Phylogenetic Distribution of CMP-Neu5Ac Hydroxylase (CMAH), the Enzyme Synthetizing the Proinflammatory Human Xenoantigen Neu5Gc

(2017) Sateesh Peri et al.   Genome Biology and Evolution

The Broad Spectrum of Human Natural Killer Cell Diversity

(2017) Aharon G. Freud et al.   IMMUNITY

HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells

(2017) Germán G Gornalusse et al.   NATURE BIOTECHNOLOGY

Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types

(2016) Kyle M. Loh et al.   CELL

Closing in on Mass Production of Mature Human Beta Cells

(2016) Timothy J. Kieffer   Cell Stem Cell

Extracellular Matrix–Mediated Maturation of Human Pluripotent Stem Cell–Derived Cardiac Monolayer Structure and Electrophysiological Function

(2016) Todd J. Herron et al.   Circulation-Arrhythmia and Electrophysiology

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

Generation of Functional Human Pancreatic β Cells In Vitro

(2014) Felicia W. Pagliuca et al.   CELL

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

Heterelogous expression of mutated HLA-G decreases immunogenicity of human embryonic stem cells and their epidermal derivatives

(2014) Longmei Zhao et al.   Stem Cell Research

Path to the Clinic: Assessment of iPSC-Based Cell Therapies In Vivo in a Nonhuman Primate Model

(2014) So Gun Hong et al.   Cell Reports

Revascularization of Transplanted Pancreatic Islets and Role of the Transplantation Site

(2013) Andrew R. Pepper et al.   Clinical & Developmental Immunology

Bioengineered Sites for Islet Cell Transplantation

(2013) Sophie Vériter et al.   Current Diabetes Reports

Biowire: a platform for maturation of human pluripotent stem cell–derived cardiomyocytes

(2013) Sara S Nunes et al.   NATURE METHODS

No monkey business: why studying NK cells in non-human primates pays off

(2013) Henoch S. Hong et al.   Frontiers in Immunology

Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2

(2012) Margit H. Lampen et al.   MOLECULAR IMMUNOLOGY

Letter to the Glyco-Forum: Since there are PAMPs and DAMPs, there must be SAMPs? Glycan "self-associated molecular patterns" dampen innate immunity, but pathogens can mimic them

(2011) A. Varki   GLYCOBIOLOGY

Islet Transplantation: Alternative Sites

(2010) Amer Rajab   Current Diabetes Reports

Functionally distinct subsets of human NK cells and monocyte/DC-like cells identified by coexpression of CD56, CD7, and CD4

(2009) J. M. Milush et al.   BLOOD