Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosa
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Drug resistance and physiological roles of RND multidrug efflux pumps in Salmonella enterica, Escherichia coli and Pseudomonas aeruginosa
Authors
Keywords
-
Journal
MICROBIOLOGY-SGM
Volume 169, Issue 6, Pages -
Publisher
Microbiology Society
Online
2023-06-16
DOI
10.1099/mic.0.001322
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Cryo-EM Structures of AcrD Illuminate a Mechanism for Capturing Aminoglycosides from Its Central Cavity
- (2023) Zhemin Zhang et al. mBio
- A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB
- (2022) Ilyas Alav et al. Scientific Reports
- Multidrug Resistance Efflux Pumps in Acinetobacter spp.: An Update
- (2021) Vanessa Kornelsen et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Physiological Functions of Bacterial “Multidrug” Efflux Pumps
- (2021) Peter J. F. Henderson et al. CHEMICAL REVIEWS
- Interactive Tree Of Life (iTOL) v5: an online tool for phylogenetic tree display and annotation
- (2021) Ivica Letunic et al. NUCLEIC ACIDS RESEARCH
- The Building Blocks of Antimicrobial Resistance in Pseudomonas aeruginosa: Implications for Current Resistance-Breaking Therapies
- (2021) R. Frèdi Langendonk et al. Frontiers in Cellular and Infection Microbiology
- Ever-Adapting RND Efflux Pumps in Gram-Negative Multidrug-Resistant Pathogens: A Race against Time
- (2021) Martijn Zwama et al. Antibiotics-Basel
- Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump
- (2020) Kamil Górecki et al. PLoS One
- Crystal structure of the multidrug resistance regulator RamR complexed with bile acids
- (2019) Suguru Yamasaki et al. Scientific Reports
- AcrB: a mean, keen, drug efflux machine
- (2019) Jessica Kobylka et al. Annals of the New York Academy of Sciences
- Kalign 3: multiple sequence alignment of large datasets
- (2019) Timo Lassmann BIOINFORMATICS
- Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB
- (2019) Heng-Keat Tam et al. JOURNAL OF MOLECULAR BIOLOGY
- Selection for increased quorum-sensing cooperation in Pseudomonas aeruginosa through the shut-down of a drug resistance pump
- (2018) Ron D. Oshri et al. ISME Journal
- Coordinated Expression of acrAB-tolC and Eight Other Functional Efflux Pumps Through Activating ramA and marA in Salmonella enterica serovar Typhimurium
- (2018) Chuan-Zhen Zhang et al. Microbial Drug Resistance
- Pseudomonas aeruginosa PumA acts on an endogenous phenazine to promote self-resistance
- (2018) Abigail J. Sporer et al. MICROBIOLOGY-SGM
- molecular mechanisms of AcrB-mediated multidrug export
- (2018) martijn zwama et al. RESEARCH IN MICROBIOLOGY
- Multiple entry pathways within the efflux transporter AcrB contribute to multidrug recognition
- (2018) Martijn Zwama et al. Nature Communications
- Heterogeneity in efflux pump expression predisposes antibiotic-resistant cells to mutation
- (2018) Imane El Meouche et al. SCIENCE
- The CpxR/CpxA system contributes to Salmonella gold-resistance by controlling the GolS-dependent gesABC transcription
- (2017) Sebastián Cerminati et al. ENVIRONMENTAL MICROBIOLOGY
- CsrA maximizes expression of the AcrAB multidrug resistance transporter
- (2017) Vito Ricci et al. NUCLEIC ACIDS RESEARCH
- Secondary multidrug efflux pump mutants alter Escherichia coli biofilm growth in the presence of cationic antimicrobial compounds
- (2017) Denice C. Bay et al. RESEARCH IN MICROBIOLOGY
- Metabolic Compensation of Fitness Costs Is a General Outcome for Antibiotic-Resistant Pseudomonas aeruginosa Mutants Overexpressing Efflux Pumps
- (2017) Jorge Olivares Pacheco et al. mBio
- Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium
- (2017) Xuan Wang-Kan et al. mBio
- An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump
- (2017) Zhao Wang et al. eLife
- Kinetic Control of Quorum Sensing in Pseudomonas aeruginosa by Multidrug Efflux Pumps
- (2017) David Wolloscheck et al. ACS Infectious Diseases
- Potentiation of Aminoglycoside Activity in Pseudomonas aeruginosa by Targeting the AmgRS Envelope Stress-Responsive Two-Component System
- (2016) Keith Poole et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Real-Time Monitoring of nfxB Mutant Occurrence and Dynamics in Pseudomonas aeruginosa Biofilm Exposed to Subinhibitory Concentrations of Ciprofloxacin
- (2016) Greta Zaborskyte et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Phenotype microarray analysis of the drug efflux systems in Salmonella enterica serovar Typhimurium
- (2016) Seiji Yamasaki et al. JOURNAL OF INFECTION AND CHEMOTHERAPY
- ThePseudomonas aeruginosaefflux pump MexGHI-OpmD transports a natural phenazine that controls gene expression and biofilm development
- (2016) Hassan Sakhtah et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Beyond Antimicrobial Resistance: Evidence for a Distinct Role of the AcrD Efflux Pump in Salmonella Biology
- (2016) Michelle M. C. Buckner et al. mBio
- MdsABC-Mediated Pathway for Pathogenicity in Salmonella enterica Serovar Typhimurium
- (2015) Saemee Song et al. INFECTION AND IMMUNITY
- Multidrug efflux pumps contribute to Escherichia coli biofilm maintenance
- (2015) Seiji Yamasaki et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Biofilm formation ability of Salmonella enterica serovar Typhimurium acrAB mutants
- (2015) Dov B. Schlisselberg et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- SuhB is a novel ribosome associated protein that regulates expression of MexXY by modulating ribosome stalling inPseudomonas aeruginosa
- (2015) Jing Shi et al. MOLECULAR MICROBIOLOGY
- Homologs of the Acinetobacter baumannii AceI Transporter Represent a New Family of Bacterial Multidrug Efflux Systems
- (2015) Karl A. Hassan et al. mBio
- Overexpression of MexCD-OprJ Reduces Pseudomonas aeruginosa Virulence by Increasing Its Susceptibility to Complement-Mediated Killing
- (2014) Inmaculada Martínez-Ramos et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa
- (2014) Joseph D. Moore et al. CHEMBIOCHEM
- Salmonella enterica serovar Typhimurium multidrug efflux pumps EmrAB and AcrEF support the major efflux system AcrAB in decreased susceptibility to triclosan
- (2014) Ulrike Rensch et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Bile-mediated activation of the acrAB and tolC multidrug efflux genes occurs mainly through transcriptional derepression of ramA in Salmonella enterica serovar Typhimurium
- (2014) S. Baucheron et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Expression of homologous RND efflux pump genes is dependent upon AcrB expression: implications for efflux and virulence inhibitor design
- (2014) Jessica M. A. Blair et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- β-Lactam Selectivity of Multidrug Transporters AcrB and AcrD Resides in the Proximal Binding Pocket
- (2014) Naoki Kobayashi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- AmgRS-mediated envelope stress-inducible expression of themexXYmultidrug efflux operon ofPseudomonas aeruginosa
- (2014) Calvin Ho-Fung Lau et al. MicrobiologyOpen
- Transcriptome profiling reveals links between ParS/ParR, MexEF-OprN, and quorum sensing in the regulation of adaptation and virulence in Pseudomonas aeruginosa
- (2013) Dongping Wang et al. BMC GENOMICS
- Development of Ceftriaxone Resistance Affects the Virulence Properties of Salmonella enterica Serotype Typhimurium Strains
- (2013) Liang Li et al. Foodborne Pathogens and Disease
- Cooperation of the multidrug efflux pump and lipopolysaccharides in the intrinsic antibiotic resistance of Salmonella enterica serovar Typhimurium
- (2013) Seiji Yamasaki et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Inhibition of multidrug efflux as a strategy to prevent biofilm formation
- (2013) S. Baugh et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Genetic inactivation of acrAB or inhibition of efflux induces expression of ramA
- (2013) A. J. Lawler et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Regulation of acrAB expression by cellular metabolites in Escherichia coli
- (2013) C. Ruiz et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The MerR-Like Regulator BrlR Confers Biofilm Tolerance by Activating Multidrug Efflux Pumps in Pseudomonas aeruginosa Biofilms
- (2013) J. Liao et al. JOURNAL OF BACTERIOLOGY
- The BaeSR regulon is involved in defense against zinc toxicity in E. coli
- (2013) Da Wang et al. Metallomics
- Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ
- (2013) Thomas Hay et al. PLoS One
- Human Host Defense Peptide LL-37 Stimulates Virulence Factor Production and Adaptive Resistance in Pseudomonas aeruginosa
- (2013) Nikola Strempel et al. PLoS One
- The crystal structure of multidrug-resistance regulator RamR with multiple drugs
- (2013) Suguru Yamasaki et al. Nature Communications
- Hypoxia Increases Antibiotic Resistance in Pseudomonas aeruginosa through Altering the Composition of Multidrug Efflux Pumps
- (2012) Bettina Schaible et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication
- (2012) Shu Minagawa et al. BMC MICROBIOLOGY
- Overproduction of the multidrug efflux pump MexEF-OprN does not impair Pseudomonas aeruginosa fitness in competition tests, but produces specific changes in bacterial regulatory networks
- (2012) Jorge Olivares et al. ENVIRONMENTAL MICROBIOLOGY
- Loss of or inhibition of all multidrug resistance efflux pumps of Salmonella enterica serovar Typhimurium results in impaired ability to form a biofilm
- (2012) S. Baugh et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- MexT Functions as a Redox-Responsive Regulator Modulating Disulfide Stress Resistance in Pseudomonas aeruginosa
- (2012) E. Fargier et al. JOURNAL OF BACTERIOLOGY
- Effects of Natural Mutations in the ramRA Locus on Invasiveness of Epidemic Fluoroquinolone-Resistant Salmonella enterica Serovar Typhimurium Isolates
- (2012) Etienne Giraud et al. JOURNAL OF INFECTIOUS DISEASES
- Lethality and cooperation of Pseudomonas aeruginosa quorum-sensing mutants in Drosophila melanogaster infection models
- (2012) E. I. Lutter et al. MICROBIOLOGY-SGM
- Structure and mechanism of the tripartite CusCBA heavy-metal efflux complex
- (2012) F. Long et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- The Regulatory Repertoire of Pseudomonas aeruginosa AmpC ß-Lactamase Regulator AmpR Includes Virulence Genes
- (2012) Deepak Balasubramanian et al. PLoS One
- Transport of drugs by the multidrug transporter AcrB involves an access and a deep binding pocket that are separated by a switch-loop
- (2012) T. Eicher et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Effects of indole on drug resistance and virulence of Salmonella enterica serovar Typhimurium revealed by genome-wide analyses
- (2012) Eiji Nikaido et al. Gut Pathogens
- Roles of Multidrug Efflux Pumps on the Biofilm Formation of Escherichia coli K-12
- (2011) KAYO MATSUMURA et al. BIOCONTROL SCIENCE
- Development of antibiotic resistance and up-regulation of the antimutator gene pfpI in mutator Pseudomonas aeruginosa due to inactivation of two DNA oxidative repair genes (mutY, mutM)
- (2011) Lotte Frigaard Mandsberg et al. FEMS MICROBIOLOGY LETTERS
- AcrA dependency of the AcrD efflux pump in Salmonella enterica serovar Typhimurium
- (2011) Seiji Yamasaki et al. JOURNAL OF ANTIBIOTICS
- Characterization of the Induction and Cellular Role of the BaeSR Two-Component Envelope Stress Response of Escherichia coli
- (2011) S. K. D. Leblanc et al. JOURNAL OF BACTERIOLOGY
- Switch or Funnel: How RND-Type Transport Systems Control Periplasmic Metal Homeostasis
- (2011) E.-H. Kim et al. JOURNAL OF BACTERIOLOGY
- The Multidrug Efflux Pump MdtEF Protects against Nitrosative Damage during the Anaerobic Respiration inEscherichia coli
- (2011) Yiliang Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Inactivation of MuxABC-OpmB transporter system in Pseudomonas aeruginosa leads to increased ampicillin and carbenicillin resistance and decreased virulence
- (2011) Liang Yang et al. JOURNAL OF MICROBIOLOGY
- Structures of the multidrug exporter AcrB reveal a proximal multisite drug-binding pocket
- (2011) Ryosuke Nakashima et al. NATURE
- A Requirement of TolC and MDR Efflux Pumps for Acid Adaptation and GadAB Induction in Escherichia coli
- (2011) Kari N. W. Deininger et al. PLoS One
- Novel Inducers of the Envelope Stress Response BaeSR in Salmonella Typhimurium: BaeR Is Critically Required for Tungstate Waste Disposal
- (2011) Corinne Appia-Ayme et al. PLoS One
- The Role of RamA on the Development of Ciprofloxacin Resistance in Salmonella enterica Serovar Typhimurium
- (2011) Yawei Sun et al. PLoS One
- MexEF-OprN Efflux Pump Exports the Pseudomonas Quinolone Signal (PQS) Precursor HHQ (4-hydroxy-2-heptylquinoline)
- (2011) Martin G. Lamarche et al. PLoS One
- Evidence of MexT-Independent Overexpression of MexEF-OprN Multidrug Efflux Pump of Pseudomonas aeruginosa in Presence of Metabolic Stress
- (2011) Ayush Kumar et al. PLoS One
- Effect of NlpE Overproduction on Multidrug Resistance in Escherichia coli
- (2010) K. Nishino et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Oxidative Stress Induction of the MexXY Multidrug Efflux Genes and Promotion of Aminoglycoside Resistance Development inPseudomonas aeruginosa
- (2010) Sebastien Fraud et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- A Two-Component Regulatory System Interconnects Resistance to Polymyxins, Aminoglycosides, Fluoroquinolones, and β-Lactams inPseudomonas aeruginosa
- (2010) Cédric Muller et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- mexEF-oprNMultidrug Efflux Operon ofPseudomonas aeruginosa: Regulation by the MexT Activator in Response to Nitrosative Stress and Chloramphenicol
- (2010) Hossam Fetar et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- TolC dependency of multidrug efflux systems in Salmonella enterica serovar Typhimurium
- (2010) Tsukasa Horiyama et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- Effect of overexpression of small non-coding DsrA RNA on multidrug efflux in Escherichia coli
- (2010) K. Nishino et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- RamA, a Member of the AraC/XylS Family, Influences Both Virulence and Efflux in Salmonella enterica Serovar Typhimurium
- (2010) A. M. Bailey et al. JOURNAL OF BACTERIOLOGY
- MexT Regulates the Type III Secretion System through MexS and PtrC in Pseudomonas aeruginosa
- (2010) Y. Jin et al. JOURNAL OF BACTERIOLOGY
- Mutation ofnfxBCauses Global Changes in the Physiology and Metabolism ofPseudomonas aeruginosa
- (2010) Hannah G. Stickland et al. JOURNAL OF PROTEOME RESEARCH
- Regulation of the AcrAB multidrug efflux pump in Salmonella enterica serovar Typhimurium in response to indole and paraquat
- (2010) E. Nikaido et al. MICROBIOLOGY-SGM
- Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport
- (2010) Feng Long et al. NATURE
- Fmt Bypass in Pseudomonas aeruginosa Causes Induction of MexXY Efflux Pump Expression
- (2009) R. E. Caughlan et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- H-NS Modulates Multidrug Resistance of Salmonella enterica Serovar Typhimurium by Repressing Multidrug Efflux Genes acrEF
- (2009) K. Nishino et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Antibiotic Resistance in Pseudomonas aeruginosa Strains with Increased Mutation Frequency Due to Inactivation of the DNA Oxidative Repair System
- (2009) L. F. Mandsberg et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Regulation and physiological function of multidrug efflux pumps in Escherichia coli and Salmonella
- (2009) Kunihiko Nishino et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Efflux pump inhibitors reduce the invasiveness of Pseudomonas aeruginosa
- (2009) Yoichi Hirakata et al. INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
- Periplasmic adaptor protein AcrA has a distinct role in the antibiotic resistance and virulence of Salmonella enterica serovar Typhimurium
- (2009) J. M. A. Blair et al. JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY
- The Global Consequence of Disruption of the AcrAB-TolC Efflux Pump in Salmonella enterica Includes Reduced Expression of SPI-1 and Other Attributes Required To Infect the Host
- (2009) M. A. Webber et al. JOURNAL OF BACTERIOLOGY
- MexT modulates virulence determinants in Pseudomonas aeruginosa independent of the MexEF-OprN efflux pump
- (2009) Zhe-Xian Tian et al. MICROBIAL PATHOGENESIS
- Gene cloning and characteristics of the RND-type multidrug efflux pump MuxABC-OpmB possessing two RND components in Pseudomonas aeruginosa
- (2009) T. Mima et al. MICROBIOLOGY-SGM
- Repression of Invasion Genes and Decreased Invasion in a High-Level Fluoroquinolone-Resistant Salmonella Typhimurium Mutant
- (2009) Anna Fàbrega et al. PLoS One
- MexCD-OprJ Multidrug Efflux System of Pseudomonas aeruginosa: Involvement in Chlorhexidine Resistance and Induction by Membrane-Damaging Agents Dependent upon the AlgU Stress Response Sigma Factor
- (2008) S. Fraud et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- Resistance and Virulence of Pseudomonas aeruginosa Clinical Strains Overproducing the MexCD-OprJ Efflux Pump
- (2008) K. Jeannot et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- TolC, but not AcrB, is involved in the invasiveness of multidrug-resistant Salmonella enterica serovar Typhimurium by increasing type III secretion system-1 expression
- (2008) Isabelle Virlogeux-Payant et al. INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY
- mgtA Expression Is Induced by Rob Overexpression and Mediates a Salmonella enterica Resistance Phenotype
- (2008) J. Barchiesi et al. JOURNAL OF BACTERIOLOGY
- AcrAB Multidrug Efflux Pump Regulation inSalmonella entericaserovar Typhimurium by RamA in Response to Environmental Signals
- (2008) Eiji Nikaido et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Contact-dependent growth inhibition requires the essential outer membrane protein BamA (YaeT) as the receptor and the inner membrane transport protein AcrB
- (2008) Stephanie K. Aoki et al. MOLECULAR MICROBIOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More