Active Efflux Influences the Potency of Quorum Sensing Inhibitors inPseudomonas aeruginosa

Combating Multidrug-Resistant Bacteria: Current Strategies for the Discovery of Novel Antibacterials

(2013) Kieron M. G. O'Connell et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

(2013) C. T. O'Loughlin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bacterial Quorum Sensing: Its Role in Virulence and Possibilities for Its Control

(2013) S. T. Rutherford et al.   Cold Spring Harbor Perspectives in Medicine

2-Aminobenzimidazole Derivatives Strongly Inhibit and DispersePseudomonas aeruginosaBiofilms

(2012) Reto Frei et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication

(2012) Shu Minagawa et al.   BMC MICROBIOLOGY

Understanding efflux in Gram-negative bacteria: opportunities for drug discovery

(2012) Herbert P Schweizer   Expert Opinion on Drug Discovery

Lethality and cooperation of Pseudomonas aeruginosa quorum-sensing mutants in Drosophila melanogaster infection models

(2012) E. I. Lutter et al.   MICROBIOLOGY-SGM

A dynamic and intricate regulatory network determines Pseudomonas aeruginosa virulence

(2012) Deepak Balasubramanian et al.   NUCLEIC ACIDS RESEARCH

Inhibition of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells by quorum sensing autoinducer-mimics

(2012) Bernardas Morkunas et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design, synthesis, and biological evaluation of abiotic, non-lactone modulators of LuxR-type quorum sensing

(2011) Christine E. McInnis et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second-Generation Libraries of N-Acylated L-Homoserine Lactones

(2011) Margrith E. Mattmann et al.   CHEMBIOCHEM

MexEF-OprN Efflux Pump Exports the Pseudomonas Quinolone Signal (PQS) Precursor HHQ (4-hydroxy-2-heptylquinoline)

(2011) Martin G. Lamarche et al.   PLoS One

The BpeAB-OprB Efflux Pump of Burkholderia pseudomallei 1026b Does Not Play a Role in Quorum Sensing, Virulence Factor Production, or Extrusion of Aminoglycosides but Is a Broad-Spectrum Drug Efflux System

(2010) T. Mima et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Quorum Sensing in Gram-Negative Bacteria: Small-Molecule Modulation of AHL and AI-2 Quorum Sensing Pathways

(2010) Warren R. J. D. Galloway et al.   CHEMICAL REVIEWS

Small Molecules That Modulate Quorum Sensing and Control Virulence inPseudomonas aeruginosa

(2010) Margrith E. Mattmann et al.   JOURNAL OF ORGANIC CHEMISTRY

D-Amino Acids Trigger Biofilm Disassembly

(2010) I. Kolodkin-Gal et al.   SCIENCE

Efflux-Mediated Drug Resistance in Bacteria

(2009) Xian-Zhi Li et al.   DRUGS

Covalent Inhibition of Bacterial Quorum Sensing

(2009) Neri Amara et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Evaluation of a focused library of N-aryl l-homoserine lactones reveals a new set of potent quorum sensing modulators

(2008) Grant D. Geske et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Comparative Analyses ofN-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

(2008) Grant D. Geske et al.   CHEMBIOCHEM

Expanding dialogues: from natural autoinducers to non-natural analogues that modulate quorum sensing in Gram-negative bacteria

(2008) Grant D. Geske et al.   CHEMICAL SOCIETY REVIEWS

Synthetic ligands that activate and inhibit a quorum-sensing regulator in Pseudomonas aeruginosa

(2007) Margrith E. Mattmann et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS