Colon-specific delivery of methotrexate using hyaluronic acid modified pH-responsive nanocarrier for the therapy of colitis in mice

PLGA-Based Composites for Various Biomedical Applications

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Dual Functional Eudragit® S100/L30D-55 and PLGA Colon-Targeted Nanoparticles of Iridoid Glycoside for Improved Treatment of Induced Ulcerative Colitis

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Chitosan-based blends for biomedical applications

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Colon-targeted delivery of tacrolimus using pH-responsive polymeric nanoparticles for murine colitis therapy

(2021) Xiaoran Cai et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Lentinan-Based Oral Nanoparticle Loaded Budesonide With Macrophage-Targeting Ability for Treatment of Ulcerative Colitis

(2021) Meisi Lin et al.   Frontiers in Bioengineering and Biotechnology

Interferon Lambda in the Pathogenesis of Inflammatory Bowel Diseases

(2021) Jonathan W. Wallace et al.   Frontiers in Immunology

Hyaluronic Acid: A Key Ingredient in the Therapy of Inflammation

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Methotrexate and its mechanisms of action in inflammatory arthritis

(2020) Bruce N. Cronstein et al.   Nature Reviews Rheumatology

A Novel Strategy for Treating Inflammatory Bowel Disease by Targeting Delivery of Methotrexate through Glucan Particles

(2020) Ying Sun et al.   Advanced Healthcare Materials

Puerarin inhibits inflammation and oxidative stress in dextran sulfate sodium-induced colitis mice model

(2020) Yong-Deok Jeon et al.   BIOMEDICINE & PHARMACOTHERAPY

The Antioxidant and Anti-Inflammatory Properties of Anacardium occidentale L. Cashew Nuts in a Mouse Model of Colitis

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Interventions of natural and synthetic agents in inflammatory bowel disease, modulation of nitric oxide pathways

(2020) Aida Kamalian et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Paeoniflorin ameliorates experimental colitis by inhibiting gram-positive bacteria-dependent MDP-NOD2 pathway

(2020) Xia Luo et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Hyaluronic acid-coated polymeric micelles with hydrogen peroxide scavenging to encapsulate statins for alleviating atherosclerosis

(2020) Dan Mu et al.   JOURNAL OF NANOBIOTECHNOLOGY

Immune cell trafficking and retention in inflammatory bowel disease: mechanistic insights and therapeutic advances

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Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Dietary risk factors for inflammatory bowel diseases in a high-risk population: Results from the Faroese IBD study

(2019) T Hammer et al.   United European Gastroenterology Journal

Preparation and In Vitro/In Vivo Characterization of Polymeric Nanoparticles Containing Methotrexate to Improve Lymphatic Delivery

(2019) Ji-Hun Jang et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Macrophages in intestinal inflammation and resolution: a potential therapeutic target in IBD

(2019) Yi Rang Na et al.   Nature Reviews Gastroenterology & Hepatology

Microbial genes and pathways in inflammatory bowel disease

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Nanoparticles Targeting Macrophages as Potential Clinical Therapeutic Agents Against Cancer and Inflammation

(2019) Guorong Hu et al.   Frontiers in Immunology

Preclinical Study in Vivo for New Pharmacological Approaches in Inflammatory Bowel Disease: A Systematic Review of Chronic Model of TNBS-Induced Colitis

(2019) Silva et al.   Journal of Clinical Medicine

Deletion of IL-6 exacerbates colitis and induces systemic inflammation in IL-10-deficient mice

(2019) Mei Ye et al.   Journal of Crohns & Colitis

Interrogating host immunity to predict treatment response in inflammatory bowel disease

(2019) Jonathan L. Digby-Bell et al.   Nature Reviews Gastroenterology & Hepatology

Host–microbiota interactions in inflammatory bowel disease

(2019) Markus F. Neurath   Nature Reviews Gastroenterology & Hepatology

A novel combination of astilbin and low-dose methotrexate respectively targeting A 2A AR and its ligand adenosine for the treatment of collagen-induced arthritis

(2018) Yuxiang Ma et al.   BIOCHEMICAL PHARMACOLOGY

Surface-modified PLGA nanoparticles with chitosan for oral delivery of tolbutamide

(2018) Yongli Shi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Mucoadhesive nanostructured polyelectrolytes complexes modulate the intestinal permeability of methotrexate

(2018) Fernanda Isadora Boni et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Methotrexate mechanism in treatment of rheumatoid arthritis

(2018) Benjamin Friedman et al.   JOINT BONE SPINE

TGF-β in inflammatory bowel disease: a key regulator of immune cells, epithelium, and the intestinal microbiota

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Crohn's disease

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Chemically induced mouse models of acute and chronic intestinal inflammation

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Environmental triggers in IBD: a review of progress and evidence

(2017) Ashwin N. Ananthakrishnan et al.   Nature Reviews Gastroenterology & Hepatology

Current and emerging therapeutic targets for IBD

(2017) Markus F. Neurath   Nature Reviews Gastroenterology & Hepatology

miRNA-133a-UCP2 pathway regulates inflammatory bowel disease progress by influencing inflammation, oxidative stress and energy metabolism

(2017) Xi Jin et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

(2016) Emilie Viennois et al.   CANCER RESEARCH

Gut Microbiota: A Key Modulator of Intestinal Healing in Inflammatory Bowel Disease

(2016) L.R. Lopetuso et al.   DIGESTIVE DISEASES

Biology: A slow-motion epidemic

(2016) Michael Eisenstein   NATURE

Fecal Lipocalin-2 as a Sensitive and Noninvasive Biomarker in the TNBS Crohn’s Inflammatory Bowel Disease Model

(2016) Heidi Hsieh et al.   TOXICOLOGIC PATHOLOGY

The global burden of IBD: from 2015 to 2025

(2015) Gilaad G. Kaplan   Nature Reviews Gastroenterology & Hepatology

Antioxidant therapy for treatment of inflammatory bowel disease: Does it work?

(2015) Fabiana Andréa Moura et al.   Redox Biology

Hirsutenone reduces deterioration of tight junction proteins through EGFR/Akt and ERK1/2 pathway both converging to HO-1 induction

(2014) Geom Seog Seo et al.   BIOCHEMICAL PHARMACOLOGY

Methotrexate: an old new drug in autoimmune disease

(2014) Paola Cipriani et al.   Expert Review of Clinical Immunology

Enhanced gene delivery efficiency of cationic liposomes coated with PEGylated hyaluronic acid for anti P-glycoprotein siRNA: A potential candidate for overcoming multi-drug resistance

(2014) Rui Ran et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Bioresponsive Hyaluronic Acid-Capped Mesoporous Silica Nanoparticles for Targeted Drug Delivery

(2013) Zhaowei Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

pH-Sensitive Nanoparticles of Curcumin–Celecoxib Combination: Evaluating Drug Synergy in Ulcerative Colitis Model

(2013) Dalapathi Gugulothu et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Targeted Drug Delivery to Intestinal Macrophages by Bioactive Nanovesicles Released from Grapefruit

(2013) Baomei Wang et al.   MOLECULAR THERAPY

Rational Mutational Analysis of a Multidrug MFS Transporter CaMdr1p of Candida albicans by Employing a Membrane Environment Based Computational Approach

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